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N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt

CAS No.
2100306-47-4
Chemical Name:
N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt
Synonyms
GUN 06474;N-(Amino-PEG1)-N-bis(PEG2-propargyl);N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt;Ethanamine, 2-(2-aminoethoxy)-N,N-bis[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-
CBNumber:
CB83373671
Molecular Formula:
C18H32N2O5
Molecular Weight:
356.46
MDL Number:
MFCD31814447
MOL File:
2100306-47-4.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:55

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt Properties

Boiling point 443.9±40.0 °C(Predicted)
Density 1.061±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO
pka 8.83±0.10(Predicted)

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114830 N-(Amino-PEG1)-N-bis(PEG2-propargyl) 98.0% 2100306-47-4 25mg $135 2026-06-04 Buy
ChemScene CS-0114830 N-(Amino-PEG1)-N-bis(PEG2-propargyl) 98.0% 2100306-47-4 50mg $217 2026-06-04 Buy
ChemScene CS-0114830 N-(Amino-PEG1)-N-bis(PEG2-propargyl) 98.0% 2100306-47-4 100mg $347 2026-06-04 Buy
BroadPharm bp-23580 N-(Amino-PEG1)-N-bis(PEG2-propargyl) 98% 2100306-47-4 100MG $290 2026-05-24 Buy
BroadPharm bp-23580 N-(Amino-PEG1)-N-bis(PEG2-propargyl) 98% 2100306-47-4 250MG $530 2026-05-24 Buy
Product number Packaging Price Buy
CS-0114830 25mg $135 Buy
CS-0114830 50mg $217 Buy
CS-0114830 100mg $347 Buy
bp-23580 100MG $290 Buy
bp-23580 250MG $530 Buy

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt Chemical Properties, Uses, Production

Description

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt is a crosslinker consisting of an amino group with two propargyl groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl groups can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry.

Uses

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1577 58
Zhejiang Rui 'ao Biological Technology Co.,LTD. 82087565 15757883359 yan@ruiaochem.cn China 712 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Henan Weitixi Chemical Technology Co., Ltd 0371-53370800 18037197114 3807961510@qq.com China 9996 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38900 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com 18017580634 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Wanxin Biotechnology (Jiaxing) Co., LTD 0573-83568680 18057391398 3956524501@qq.com China 1441 58

View Latest Price from N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(Amino-PEG1)-N-bis(PEG2-propargyl) pictures 2025-06-07 N-(Amino-PEG1)-N-bis(PEG2-propargyl)
2100306-47-4
500mg >95.00% 500mg Xian confluore Biological Technology Co., Ltd.

2100306-47-4 (N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt) Related Search:

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt N-(Amino-PEG1)-N-bis(PEG2-propargyl) GUN 06474 Ethanamine, 2-(2-aminoethoxy)-N,N-bis[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]- 2100306-47-4