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Acetosyringone

Acetosyringone Structure
Acetosyringone structure
CAS No.
2478-38-8
Chemical Name:
Acetosyringone
Synonyms
Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)-;3,5-DIMETHOXY-4-HYDROXYACETOPHENONE;1-(4-hydroxy-3,5-diMethoxyphenyl)ethan-1-one;3',5'-DIMETHOXY-4'-HYDROXYACETOPHENONE;1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone;Syringylethanone;4-acetylsyringol;4-HYDROXY-3,5-DIMETHOXYACETOPHENONE;5'SYRINGACETONE
CBNumber:
CB8408295
Molecular Formula:
C10H12O4
Molecular Weight:
196.2
MDL Number:
MFCD00008748
MOL File:
2478-38-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-27 11:54:19
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Acetosyringone Properties

Melting point 124-127 °C(lit.)
Boiling point 293.08°C (rough estimate)
Density 1.2166 (rough estimate)
refractive index 1.5430 (estimate)
FLAVIS Number 07.164 | 4-Hydroxy-3,5-dimethoxyacetophenone
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Powder
pka 8.19±0.23(Predicted)
color Beige to light brown
Odor at 100.00%. odorless
Water Solubility soluble
BRN 1966119
Henry's Law Constant 5.0×105 mol/(m3Pa) at 25℃, McFall et al. (2020)
InChI 1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3
InChIKey OJOBTAOGJIWAGB-UHFFFAOYSA-N
SMILES COc1cc(cc(OC)c1O)C(C)=O
LogP 1.699 (est)
CAS DataBase Reference 2478-38-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 866P45Y84S
NIST Chemistry Reference Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)-(2478-38-8)
EPA Substance Registry System Acetosyringone (2478-38-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  AM8440000
F  10
Hazard Note  Irritant
HS Code  29145090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

Acetosyringone price More Price(91)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D134406 3′,5′-Dimethoxy-4′-hydroxyacetophenone 97% 2478-38-8 1g $51.6 2026-04-30 Buy
Sigma-Aldrich D134406 3′,5′-Dimethoxy-4′-hydroxyacetophenone 97% 2478-38-8 5g $157 2026-04-30 Buy
TCI Chemical D2666 4'-Hydroxy-3',5'-dimethoxyacetophenone >98.0%(GC) 2478-38-8 5g $92 2026-04-30 Buy
TCI Chemical D2666 4'-Hydroxy-3',5'-dimethoxyacetophenone >98.0%(GC) 2478-38-8 25g $301 2026-04-30 Buy
Cayman Chemical 23224 Acetosyringone ≥98% 2478-38-8 1g $33 2026-04-30 Buy
Product number Packaging Price Buy
D134406 1g $51.6 Buy
D134406 5g $157 Buy
D2666 5g $92 Buy
D2666 25g $301 Buy
23224 1g $33 Buy

Acetosyringone Chemical Properties, Uses, Production

Uses

4’-Hydroxy-3’,5’-dimethoxyacetophenone used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents. It is a naturally occuring compound found in plants and used in plant-pathogen recognition.

Description

Acetosyringone is a phenol secreted by wounded plant tissues. It induces expression of virulence A genes and chemotaxis in A. tumefaciens strains that contain a tumor-inducing plasmid used to transfer genetic information to plant cells. Acetosyringone is widely used to increase efficacy of genetic transformation for the creation of genetically modified dicotyledonous and monocotyledonous plants.

Chemical Properties

beige to light brown crystalline powder

Uses

insect attractant, plant hormone

Uses

A buffer also known as acetosyringone that is used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents in vitro.

Uses

4’-Hydroxy-3’,5’-dimethoxyacetophenone used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents. It is a naturally occuring compound found in plants and used in plant-pathogen recognition.

Preparation

Preparation by adding a solution of 4-hydroxy-3- iodo-5-methoxyacetophenone and cupric chloride in DMF to a solution of sodium methoxide in methanol and heating between 105° and 120° (86%).

Definition

ChEBI: A member of the class of acetophenones that is 1-phenylethanone substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5.

References

[1] SHAW C H. Swimming against the tide: Chemotaxis in Agrobacterium[J]. BioEssays, 1991, 13 1: 25-29. DOI: 10.1002/bies.950130105
[2] YONG-WOOG LEE . The sensing of plant signal molecules by Agrobacterium: genetic evidence for direct recognition of phenolic inducers by the VirA protein[J]. Gene, 1996, 179 1: Pages 83-88. DOI: 10.1016/s0378-1119(96)00328-9
[3] RAMACHANDRAN SRINIVASAN  Kodiveri M G. Synergistic Action of D-Glucose and Acetosyringone on Agrobacterium Strains for Efficient Dunaliella Transformation.[J]. PLoS ONE, 2016: e0158322. DOI: 10.1371/journal.pone.0158322

Acetosyringone synthesis

28343-22-8
2478-38-8
Synthesis of Acetosyringone from Phenol, 4-ethenyl-2,6-dimethoxy-

Acetosyringone Preparation Products And Raw materials

Raw materials

2,6-Dimethoxyphenol Toluene Acetyl chloride Aluminum chloride Benzene
Hydrochloric acid Nitrobenzene Pyridine 2,6-Dimethoxyphenylacetate 1-(3,4-dihydroxy-5-methoxy-phenyl)ethanone
Acetic acid, 2-(4-acetyl-2,6-dimethoxyphenoxy)- 3,5-Dimethoxy-4-hydroxyphenylmethyl carbinol Phenol, 4-ethenyl-2,6-dimethoxy- 1-(2-hydroxy-3,5-dimethoxyphenyl)ethan-1-one α-Bromoacetosyringone
Phenol, 4-ethyl-2,6-dimethoxy- 3',5'-Dimethoxyacetophenone 3',4',5'-Trimethoxyacetophenone

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Preparation Products

Acetosyringone Suppliers

Global Suppliers ( 497)
Supplier Tel Email Country ProdList Advantage
Nanjing Search Biotech Co., Ltd +86-025-81682922 +86-13515111588 sales@searchbio.com.cn China 137 68
Shanghai QiQiao Biological Technology Co., Ltd. 021-37653318 15221675714 515366396@qq.com China 2087 58
Hu' nan Yunbang Pharmaceutical Co., Ltd. 88532689 15386497078 yunbang@yunbangapi.com China 6935 58
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9954 58
Shenyang Yijia Biomedical Technology Co., Ltd. 13998815952 sale_ekar@163.com China 19 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Nanjing Search Biotech Co., Ltd 68
Shanghai QiQiao Biological Technology Co., Ltd. 58
Hu' nan Yunbang Pharmaceutical Co., Ltd. 58
Shanghai Xingui Biotechnology Co., Ltd. 58
Shenyang Yijia Biomedical Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61

View Latest Price from Acetosyringone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acetosyringone pictures 2026-09-17 Acetosyringone
2478-38-8
 1kg 99%min 100kg WUHAN FORTUNA CHEMICAL CO., LTD
Acetosyringone pictures 2026-08-27 Acetosyringone
2478-38-8
 $31.00 99.80% 10g TargetMol Chemicals Inc.
Acetosyringone pictures 2026-03-20 Acetosyringone
2478-38-8
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
  • Acetosyringone pictures
  • Acetosyringone
    2478-38-8
  • $10.00
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd

Acetosyringone Spectrum

Acetosyringone(2478-38-8)MSAcetosyringone(2478-38-8)1HNMRAcetosyringone(2478-38-8)13CNMRAcetosyringone(2478-38-8)IR1Acetosyringone(2478-38-8)IR2Acetosyringone(2478-38-8)Raman

2478-38-8 (Acetosyringone) Related Search:

4'-Hydroxyacetophenone 3,4-Dimethoxyacetophenone Acetylacetone Dimethyldimethoxysilane Acetylspiramycin
2'-Methoxyacetophenone 4'-Methoxyacetophenone 1,1-Dimethoxyethane 2'-Hydroxyacetophenone Acetaminophen
3,5-Dihydroxyacetophenone Diphenyldimethoxysilane 3',5'-Dimethoxyacetophenone Acetylsalicylic acid Dimethoxymethane
Acetylcholine Chlorophosphonazo III 2-Hydroxyacetophenone

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SYRINGACETONE 3,5-DIMETHOXY-4-HYDROXYACETOPHENONE 4'-HYDROXY-3',5'-DIMETHOXYACETOPHENONE 4-HYDROXY-3,5-DIMETHOXYACETOPHENONE ACETOSYRINGONE 1-(4-hydroxy-3,5-dimethoxyphenyl)-ethanon 1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone 1-(4-Hydroxy-3,5-dimethoxyphenyl)-ethanone (acetosyringone) 3,5-dimethoxy-4-hydroxy-acetophenon 4’-hydroxy-3’,5’-dimethoxy-acetophenon 4-Hydroksy-3',5'-dwumetoksyacetofenon 4-hydroksy-3’,5’-dwumetoksyacetofenon Acetophenone, 3,5-dimethoxy-4-hydroxy- Acetophenone, 4'-hydroxy-3',5'-dimethoxy- Acetosyringon Phenol, 4-acetyl-2,6-dimethoxy ACETOSYRINGONE(RG) 4μ-Hydroxy-3μ,5μ-dimethoxyacetophenone, Acetosyringone 2,6-Dimethoxy-4-acetylphenol 4-Acetyl-2,6-dimethoxyphenol Syringylethanone 3',5'-Dimethoxy-4'-hydroxyacetophenone ,98% 1-(3,5-Dimethoxy-4-hydroxyphenyl)ethanone 3',5'-Dimethoxy-4'-hydroxyacetophenone,97% 1-(3,5-Dimethoxy-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-2,6-dimethoxyphenol ACETOSYRINGONE SOLUTION acetosyringones JR-8399, 3',5'-Dimethoxy-4'-hydroxyacetophenone, 97% 4'-Hydroxy-3',5'-dimethoxyacetophenone> 4-Hydroxy-3,5-dimethoxyacetophennone 3,5-Dimethoxy-4-hydroxyacetophenone, Acetosyrangone 3', 5'-Dimethoxy-4'-hydroxyacetophenone (Acetosyringone) 5' Acetozyringone Acetylbutanone Acetosyringone CAS 3'.5'-Dimethoxy-4'-hydroxyacetophenone Acetosyringone in methanol Acetosyringone, phenolic compound Acetosyringone, 10 mM in DMSO ACETOSYRINGONE SOLUTION (100 mM) IN DMSO 3',5'-DIMETHOXY-4'-HYDROXYACETOPHENONE 4-acetylsyringol 1-(4-hydroxy-3,5-diMethoxyphenyl)ethan-1-one Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)- 2478-38-8 HOC6H2OCH32COCH3 KETONE C10 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks plantgrowth Aromatic Acetophenones & Derivatives (substituted)