AKOS B006681
- CAS No.
- 1204-32-6
- Chemical Name:
- AKOS B006681
- Synonyms
- Methyl 1-Methyl-1H-indole-6-carboxylate;AKOS B006681;ART-CHEM-BB B006681;RARECHEM AL BF 0557;Methyl 1-Methylindole-6-carboxylate;6-(Methoxycarbonyl)-1-methyl-1H-indole;N-Methylindole-3-carboxylicacidmethylester;1-Methyl-1H-indole-6-carboxylic acid Methyl ester;1H-Indole-6-carboxylic acid, 1-methyl-, methyl ester;1-methyl-1H-Indole-6-carboxylic acid methyl ester (9CI ACI)
- CBNumber:
- CB8452410
- Molecular Formula:
- C11H11NO2
- Molecular Weight:
- 189.21
- MDL Number:
- MFCD06245515
- MOL File:
- 1204-32-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| HS Code | 2933998090 |
AKOS B006681 price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR0195 | Methyl 1-methyl-1H-indole-6-carboxylate 98% | 1204-32-6 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0195 | Methyl 1-methyl-1H-indole-6-carboxylate 98% | 1204-32-6 | 5g | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR0195 | Methyl 1-methyl-1H-indole-6-carboxylate 98% | 1204-32-6 | 10g | $45 | 2026-06-04 | Buy |
| Matrix Scientific | 012577 | N-Methylindole-6-carboxylic acid methyl ester | 1204-32-6 | 5.00g | $30 | 2026-05-18 | Buy |
| Matrix Scientific | 012577 | N-Methylindole-6-carboxylic acid methyl ester | 1204-32-6 | 25.00g | $113 | 2026-05-18 | Buy |
AKOS B006681 Chemical Properties, Uses, Production
Synthesis
50820-65-0
74-88-4
1204-32-6
Sodium hydride (0.35 g, 8.75 mmol) was slowly added to a stirring solution of methyl 1H-indole-6-carboxylate (0.76 g, 4.34 mmol) in N,N-dimethylformamide (DMF, 10 mL) at room temperature. The resulting suspension was stirred continuously at room temperature for 30 min, followed by dropwise addition of iodomethane (0.54 mL, 8.67 mmol). The reaction mixture was continued to be stirred at room temperature for 20 hours. Upon completion of the reaction, water (20 mL) and ethyl acetate (20 mL) were added to quench the reaction. The aqueous phase was extracted with ethyl acetate (3 x 30 mL), and all organic phases were combined and dried over a phase separation column. Subsequently, the solvent was evaporated under reduced pressure to afford methyl 1-methyl-6-indolecarboxylate as an off-white solid (0.85 g, 100% yield). The product (MH+ = 190) was confirmed by LC-MS (acidic conditions). The purity of the obtained product met the requirements for subsequent use without further purification.
References
[1] Patent: WO2009/71577, 2009, A1. Location in patent: Page/Page column 43
[2] Patent: WO2010/84185, 2010, A1. Location in patent: Page/Page column 23
[3] Journal of the American Chemical Society, 2005, vol. 127, # 22, p. 8050 - 8057
[4] Chemical and Pharmaceutical Bulletin, 1999, vol. 47, # 11, p. 1538 - 1548
[5] Heterocycles, 2006, vol. 67, # 2, p. 643 - 653
AKOS B006681 Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
| Chengdu Research Accelerators Technology Co., Ltd. | 028-64353063 | reacchemical@163.com | China | 5243 | 58 |
| Shanghai Qiao Chemical Science Co., Ltd | 021-58892003 | info@qiaochem.com | China | 6065 | 65 |
View Latest Price from AKOS B006681 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | Methyl 1-Methylindole-6-carboxylate
1204-32-6
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Methyl 1-Methylindole-6-carboxylate
1204-32-6
- $1.00
- 99%
- Career Henan Chemical Co
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