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3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone structure

CAS No.: 129722-34-5

Chemical Name:: 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone

Synonyms: 7-(4-broMobutoxy)-3,4-dihydroquinolin-2(1H)-one;Aripiprazole Bromobutoxyquinoline Impurity;7-(4-Bromobutoxy)-2(1h)-3,4-Dihydroquinolinone;7-(4-BROMOBUTOXY)-3,4-DIHYDRO-2(1H)-QUINOLINONE;CL041;Aripiprazol Intermediate;Aripiprazole Impurity i;Aripiprazole impurities1775;7-(4-bromobutoxy)-3,4-dihydro-;7-(4-BROMOBUTOXY)-3 4-DIHYDROCARBOSTYRYL

CBNumber:: CB8481674

Molecular Formula:: C13H16BrNO2

Molecular Weight:: 298.18

MDL Number:: MFCD06658540

MOL File:: 129722-34-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:15:25

Product description	Number	Pack Size	Price
7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone >98.0%(HPLC)(N)	B3333	1g	$37
7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone >98.0%(HPLC)(N)	B3333	5g	$113
7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	TRC-B681960-5G	5g	$223
7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	TRC-B681960-1G	1g	$198
7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	TRC-B681960-10G	10g	$305
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3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone Properties

Melting point	110-111°C
Boiling point	463.4±45.0 °C(Predicted)
Density	1.383±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	powder to crystal
pka	14.41±0.20(Predicted)
color	White to Almost white
Stability	Hygroscopic
InChI	InChI=1S/C13H16BrNO2/c14-7-1-2-8-17-11-5-3-10-4-6-13(16)15-12(10)9-11/h3,5,9H,1-2,4,6-8H2,(H,15,16)
InChIKey	URHLNHVYMNBPEO-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC(OCCCCBr)=C2)CCC1=O
CAS DataBase Reference	129722-34-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P271-P280
HS Code	2933499090
REACH Registrations	Active

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone price More Price(77)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B3333	7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone >98.0%(HPLC)(N)	129722-34-5	1g	$37	2026-04-30	Buy
TCI Chemical	B3333	7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone >98.0%(HPLC)(N)	129722-34-5	5g	$113	2026-04-30	Buy
TRC	TRC-B681960-5G	7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	129722-34-5	5g	$223	2026-06-03	Buy
TRC	TRC-B681960-1G	7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	129722-34-5	1g	$198	2026-06-03	Buy
TRC	TRC-B681960-10G	7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one >95%(HPLC)	129722-34-5	10g	$305	2026-06-03	Buy

Product number	Packaging	Price	Buy
B3333	1g	$37	Buy
B3333	5g	$113	Buy
TRC-B681960-5G	5g	$223	Buy
TRC-B681960-1G	1g	$198	Buy
TRC-B681960-10G	10g	$305	Buy

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

An impurity in the synthesis of Aripiprazole (A771000). A degradation product in Aripiprazole tablets.

Synthesis

110-52-1

22246-18-0

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone

129722-34-5

Example-1: Preparation of 7-(4-bromobutoxy)-3,4-dihydroquinolone [BBQ] was carried out as follows: in a 3-liter, three-necked, round-bottomed flask equipped with a mechanical stirrer, a condenser, and a thermometer, 100 grams of 3,4-dihydro-7-hydroxy-2(1H)-quinolone, 397.5 grams of 1,4-dibromobutane, 42.33 grams of potassium carbonate, and 300 ml of N,N-dimethylformamide. After mixing with stirring at room temperature (30-35 °C), the reaction mixture was heated to 40-45 °C and maintained at this temperature for 1 hour. Subsequently, a second batch of potassium carbonate (42.33 g) was added and the reaction was continued at 40-45 °C for 1 hour. Next, a third batch of potassium carbonate (42.33 g) was added and the reaction was continued at the same temperature for 4-5 hours. After completion of the reaction, the mixture was cooled to room temperature, poured into 1500 ml of water and stirred for 30 minutes. Extraction was carried out by adding 500 ml of chloroform and the organic layer was washed with water after layering. The extraction was repeated once more with 500 ml of chloroform. The organic phases were combined and washed with 10% sodium hydroxide solution and after separating the layers, the chloroform layer was washed with 1500 ml of water. Subsequently, the organic solvent was removed by vacuum distillation. To remove the trace solvent, solvent exchange was performed with 2 x 250 ml of cyclohexane. To the residue, 300 ml of cyclohexane was added, stirred for 3 hours and filtered, and the solid was washed with 200 ml of cyclohexane. Finally, the product was dried in a disk dryer at 65-70 °C for 10-12 hours until the weight loss was less than 1%. The product was obtained as 148 g in 80.95% yield and 86.09% HPLC purity.

References

[1] Asian Journal of Chemistry, 2011, vol. 23, # 4, p. 1655 - 1660
[2] Arzneimittel-Forschung/Drug Research, 2006, vol. 56, # 10, p. 673 - 677
[3] Patent: WO2008/1188, 2008, A2. Location in patent: Page/Page column 8-9
[4] Journal of Medicinal Chemistry, 1998, vol. 41, # 5, p. 658 - 667
[5] Patent: US2006/79689, 2006, A1. Location in patent: Page/Page column 11

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

1,4-Dibromobutane 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Potassium carbonate N,N-Dimethylformamide

Preparation Products

3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-quinolinone

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone Suppliers

Global( 383)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Taizhou Tianhong Biochemistry Technology Co., Ltd.	0523-86132544	sales@thbiochem.com	CHINA	305	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Taizhou Tianhong Biochemistry Technology Co., Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
Shanghai Yingrui Biopharma Co.,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-30	3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone 129722-34-5		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone 129722-34-5	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2025-04-04	3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone 129722-34-5		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone
129722-34-5
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone
129722-34-5
$1.10
99.00%
Dideu Industries Group Limited

3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone
129722-34-5
98%
Henan Aochuang Chemical Co.,Ltd.

129722-34-5(3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone)Related Search:

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Ethoxyquin Quinclorac 1,4-BIS[3,4-DIHYDRO-2(1H)-QUINOLINON-7-OXY]BUTANE 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Aripiprazole Impurity a

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1-(4-BROMOBUTOXY)-4-METHYLBENZENE 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone

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Aripiprazole Impurity A (Aripip Bromo Impurity) 7-(4-Bromobutoxy)-2-oxo-1,2,3,4-tetrahydroquinoline 3,4-dihydro-7-(4-bromobutoxy)-2(1h)-quinolinone 7-(4-BROMOBUTOXY)-1,2,3,4-TETRAHYDROQUINOLINE-2-ONE 7-(4-BROMO-BUTOXY)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 7-(4-BROMOBUTOXY)-3,4-DIHYDRO-2-QUINOLINONE (1H)-7-(4'-BROMOBUTOXY)-3,4-DIHYDRO-2-QUINOLINONE Aripiprazole Impurity i Aripiprazol Intermediate 7-(4-BROMOBUTOXY)-2(1H)-3,4-DIHYDROQUINOLINONE[INTERMEDIATE FOR ARIPIPRAZOLE] 7-(4-bromobutoxy)-3,4-dihydro- 3,4-DIHYDRO-7-(4-BROMOBUTOXY)-2(1H)-QUINOLINONE/INTERMEDIATE OF ARIPIPRAZOLE 7-(4-Brombutoxy)-3,4-dihydrochinolin-2(1H)-on 3,4-DICHLORO-7(4-BROMOBUTOXY)-2-(1H)-QUINOLINONE 7-(4-BROMOBUTOXY)-3,4-DIHYDRO-2(1H)-QUINOLINONE, 99% ARIPIPRZAOLE INTERMEDIATE 7-(4-BROMOBUTOXY)-3,4-DIHYDRO-1(H)-QUINOLINE -2-ONE 7-(4-bromobuthoxy)-3,4-dihydro-2(1H)quinolinone 7-(4-BROMOBUTOXY)-3,4-DIHYDROQUINOLINE-2(1H)-ONE 7-(4-Bromobutoxy)-1,2,3,4-tetrahydro-2-oxoquinoline 2(1H)-Quinolinone, 7-(4-bromobutoxy)- 3,4-dihydro- 7-hydroxy-(4-BroMobutyloxy)-2(1H)-3,4-dihydroquinolinone 7-(4-broMobutoxy)-1,2,3,4-tetrahydroquinolin-2-one CL041 7-(4-Bromobutoxy)3,4-dihydroquinazolone (BBQ/BBE) 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone > 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2(1H)-one(For export only) 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone ISO 9001：2015 REACH 7-(4-BROMOBUTOXY)-3 4-DIHYDROCARBOSTYRYL Aripiprazole impurities1775 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinoneQ: What is 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone Q: What is the CAS Number of 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone Q: What is the storage condition of 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone Q: What are the applications of 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone TIANFU-CHEM - 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone Dimer / 7-[4-(3,4 Dihydroquinolin 2(1H) one)oxy]-3,4-dihydroquinolin 2(1H)-one 7- (4-Bromothinyloxy) -3,4-dihydro-2 (1H) - quinolone 7- (4-Bromobutyloxy) -3,4-dihydro-2 (1H) - quinolone 7-(4-Brombutoxy)-3,4-dihydrochinolin-2(1H)-one Aripiprazole Bromobutoxyquinoline Impurity 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one 7-(4-bromobutoxy)-1,2,3,4-tetrahydroquinolin-2-one, >99% 7-(4-BROMOBUTOXY)-3,4-DIHYDRO-2(1H)-QUINOLINONE 7-(4-Bromobutoxy)-2(1h)-3,4-Dihydroquinolinone 7-(4-broMobutoxy)-3,4-dihydroquinolin-2(1H)-one Aripiprazole Bromobutoxyquinoline Impurity 129722-34-5 29722-34-5 C13H16BrNO2 Aripiprazole Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Intermediates of Aripiprazole Quinoline&Isoquinoline INTERMEDIATESOFARIPIPRAZOLE