diABZI STING agonist-1 Tautomerism
- CAS No.
- 2138498-18-5
- Chemical Name:
- diABZI STING agonist-1 Tautomerism
- Synonyms
- Tautomerism;diABZI (tautomerism);diABZI STING agonist (Compound 3);diABZI STING agonist-1 Tautomerism;diABZI STING agonist 1 (compound 3);diABZI STING agonist (Compound 3) ，S8796;(E)-1-((E)-4-((E)-5-Carbamoyl-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-(3-morpholinopropoxy)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-methoxy-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[(2E)-5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]imino]-2,3-dihydro-7-[3-(4-morpholinyl)propoxy]-, (2E)-
- CBNumber:
- CB84844710
- Molecular Formula:
- C42H51N13O7
- Molecular Weight:
- 849.94
- MDL Number:
- MFCD31746907
- MOL File:
- 2138498-18-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.44±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 11.87±0.43(Predicted) |
| color | White to light yellow |
| FDA UNII | L7DUG75C36 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
diABZI STING agonist-1 Tautomerism price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 42079 | diABZI STING Agonist-1 ≥98% | 2138498-18-5 | 1mg | $105 | 2026-04-30 | Buy |
| Cayman Chemical | 42079 | diABZI STING Agonist-1 ≥98% | 2138498-18-5 | 5mg | $471 | 2026-04-30 | Buy |
| Cayman Chemical | 42079 | diABZI STING Agonist-1 ≥98% | 2138498-18-5 | 10mg | $836 | 2026-04-30 | Buy |
| Biosynth | NKD49818 | Diabzi sting agonist-1 | 2138498-18-5 | 1mg | $389.4 | 2026-06-04 | Buy |
| Biosynth | NKD49818 | Diabzi sting agonist-1 | 2138498-18-5 | 2mg | $649 | 2026-06-04 | Buy |
diABZI STING agonist-1 Tautomerism Chemical Properties, Uses, Production
Chemical Properties
diABZI STING agonist-1 Tautomerism is a potent non-nucleoside STING agonist with great potential for the treatment of human cancers.
Uses
diABZI STING agonist-1 tautomerism is a tautomerism of diABZI STING agonist-1 (HY-112921) (compound 3). diABZI STING agonist-1 tautomerism is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively[1].
in vitro
diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, it demonstrates high selectivity against more than 350 kinases tested.
in vivo
diABZI STING agonist-1 (Tautomerism) (subcutaneous injection; 2.5 mg/kg) induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo.
References
[1] Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7. DOI:10.1038/s41586-018-0705-y
diABZI STING agonist-1 Tautomerism Preparation Products And Raw materials
Raw materials
Preparation Products
diABZI STING agonist-1 Tautomerism Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu PEIP Pharmaceutical Technology Co., LTD. | 028-61715638 18011352545 | 1242335275@qq.com | China | 473 | 58 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 1365 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Latest Price from diABZI STING agonist-1 Tautomerism manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | diABZI STING agonist-1 (Tautomerism)
2138498-18-5
|
$148.00-372.00 | 99.31% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | diABZI STING agonist-1 (Tautomerism)
2138498-18-5
|
$148.00-372.00 | 99.31% | 10g | TargetMol Chemicals Inc. |
-
- diABZI STING agonist-1 (Tautomerism)
2138498-18-5
- $148.00-372.00
- 99.31%
- TargetMol Chemicals Inc.
-
- diABZI STING agonist-1 (Tautomerism)
2138498-18-5
- $148.00-372.00
- 99.31%
- TargetMol Chemicals Inc.
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