Opipramol dihydrochloride
- CAS No.
- 909-39-7
- Chemical Name:
- Opipramol dihydrochloride
- Synonyms
- ensidon;opipramolhydrochloride;insidondihydrochloride;Opipramol dihydrochloride >=98% (HPLC), solid;4-(3-(5h-dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanodihydrochloride;4-[3-(5H-dibenz(b,f)azepin-5-yl)propyl]piperazine-1-ethanol dihydrochloride;5-(gamma-(beta-hydroxyethylpiperazino)propyl)-5h-dibenzo(b,f)azepinedihydroc;4-(3-(5h-dibenzo(b,f)azepina-5-il)propil)-1-(2-idrossietil)piperazinadiclori;Opipramol DihydrochlorideQ: What is Opipramol Dihydrochloride Q: What is the CAS Number of Opipramol Dihydrochloride Q: What is the storage condition of Opipramol Dihydrochloride
- CBNumber:
- CB8504069
- Molecular Formula:
- C23H31Cl2N3O
- Molecular Weight:
- 436.41774
- MDL Number:
- MFCD00941483
- MOL File:
- 909-39-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 210° (FR M209); mp 228-230° (DE 1133729) |
|---|---|
| solubility | H2O: ~24 mg/mL |
| form | solid |
| color | yellow |
| Water Solubility | H2O: ~24mg/mL |
| InChI | 1S/C23H29N3O.2ClH/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26;;/h1-4,6-11,27H,5,12-19H2;2*1H |
| InChIKey | DLTOEESOSYKJBK-UHFFFAOYSA-N |
| SMILES | Cl[H].Cl[H].OCCN1CCN(CCCN2c3ccccc3C=Cc4ccccc24)CC1 |
| FDA UNII | B49OBI656M |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P264-P270-P273-P301+P312-P391-P501 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| RTECS | TL9100000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
Opipramol dihydrochloride price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O5889 | Opipramol dihydrochloride ≥98% (HPLC), solid | 909-39-7 | 25mg | $130 | 2026-04-30 | Buy |
| Sigma-Aldrich | O5889 | Opipramol dihydrochloride ≥98% (HPLC), solid | 909-39-7 | 100mg | $406 | 2026-04-30 | Buy |
| ChemScene | CS-0135910 | Opipramol (dihydrochloride) | 909-39-7 | 5mg | $110 | 2026-06-04 | Buy |
| ChemScene | CS-0135910 | Opipramol (dihydrochloride) | 909-39-7 | 10mg | $175 | 2026-06-04 | Buy |
| ChemScene | CS-0135910 | Opipramol (dihydrochloride) | 909-39-7 | 25mg | $352 | 2026-06-04 | Buy |
Opipramol dihydrochloride Chemical Properties, Uses, Production
Originator
Insidon,Geigy,W. Germany,1962
Uses
antidepressant, antipsychotic;'sigma antagonist
Manufacturing Process
A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.
Therapeutic Function
Antidepressant, Antipsychotic
Biological Activity
δ1/δ2 opioid receptor agonist; an antagonist at D2, 5HT2 and H1 receptors; atypical antidepressant, antipsychotic and anxiolytic
Opipramol dihydrochloride Preparation Products And Raw materials
Opipramol dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd. | 029-88380327 17691182729 | 1053@dideu.com | China | 2001 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2240 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15030 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-025-85560043 17301488900 | info@synzest.com | China | 9274 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | helen.zhang@synzest.com | China | 8283 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
