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1-(2-Hydroxyethyl)piperazine

1-(2-Hydroxyethyl)piperazine structure

CAS No.: 103-76-4

Chemical Name:: 1-(2-Hydroxyethyl)piperazine

Synonyms: 2-(Piperazin-1-yl)ethan-1-ol;N-(2-HYDROXYETHYL)PIPERAZINE;N-HYDROXYETHYLPIPERAZINE;Hydroxyethylpiperazine;1-PIPERAZINEETHANOL;2-PIPERAZIN-1-YL-ETHANOL;2-PIPERAZINOETHANOL;HydroxyethylPiperazine /1-Piperazineethanol;NSC 60706;NSC 38969

CBNumber:: CB8445089

Molecular Formula:: C6H14N2O

Molecular Weight:: 130.19

MDL Number:: MFCD00005970

MOL File:: 103-76-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-30 08:01:02

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1-(2-Hydroxyethyl)piperazine Properties

Melting point	-38.5 °C
Boiling point	246 °C(lit.)
Density	1.061 g/mL at 25 °C(lit.)
vapor pressure	0.007 hPa (20 °C)
refractive index	n20/D 1.506(lit.)
Flash point	>230 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oily Liquid
pka	14.96±0.10(Predicted)
color	Clear colorless to pale yellow
Specific Gravity	1.060
PH	12.3 (100g/l, H2O, 20℃)
explosive limit	1.4-8.9%(V)
Water Solubility	MISCIBLE
BRN	104361
Henry's Law Constant	2.9×10³ mol/(m³Pa) at 25℃, Nguyen (2013)
InChI	1S/C6H14N2O/c9-6-5-8-3-1-7-2-4-8/h7,9H,1-6H2
InChIKey	WFCSWCVEJLETKA-UHFFFAOYSA-N
SMILES	OCCN1CCNCC1
LogP	-1.47 at 25℃
CAS DataBase Reference	103-76-4(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	G7VXS31ZFP
NIST Chemistry Reference	1-Piperazineethanol(103-76-4)
EPA Substance Registry System	1-Piperazineethanol (103-76-4)
UNSPSC Code	12352104
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H315-H318

Precautionary statements

P264-P280-P302+P352-P305+P351+P338-P332+P313-P362+P364

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38-41-38

Safety Statements

26-36/39-37/39

WGK Germany

RTECS

TL6825000

Autoignition Temperature

280 °C

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29335995

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Dam. 1
Skin Irrit. 2

Toxicity

LD50 orally in Rabbit: 4000 mg/kg LD50 dermal Rabbit > 5000 mg/kg

REACH Registrations

Active

NFPA 704

	1
		0

1-(2-Hydroxyethyl)piperazine price More Price(84)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H28807	1-(2-Hydroxyethyl)piperazine 98%	103-76-4	100g	$46.4	2026-04-30	Buy
Sigma-Aldrich	H28807	1-(2-Hydroxyethyl)piperazine 98%	103-76-4	500g	$162	2026-04-30	Buy
TCI Chemical	P0812	1-(2-Hydroxyethyl)piperazine >99.0%(GC)	103-76-4	25g	$19	2026-04-30	Buy
TCI Chemical	P0812	1-(2-Hydroxyethyl)piperazine >99.0%(GC)	103-76-4	100g	$29	2026-04-30	Buy
Usbiological	278749	1-(2-Hydroxyethyl)piperazine Asreported	103-76-4	500g	$389	2026-06-03	Buy

Product number	Packaging	Price	Buy
H28807	100g	$46.4	Buy
H28807	500g	$162	Buy
P0812	25g	$19	Buy
P0812	100g	$29	Buy
278749	500g	$389	Buy

1-(2-Hydroxyethyl)piperazine Chemical Properties,Uses,Production

Description

1-(2-Hydroxyethyl)piperazine (HEP) is obtained during ethyleneamine production and used for corrosion inhibitors, pharmaceuticals, surfactants, and synthetic fibers.

Chemical Properties

clear colorless to pale yellow oily liquid

Uses

1-(2-Hydroxyethyl)piperazine is a hydroxyalkyl substituted pieprazine used in the preparation of pharmaceutical compounds such as neuroleptic agents.

Uses

1-Piperazineethanol is a hydroxyalkyl substituted pieprazine used in the preparation of pharmaceutical compounds such as neuroleptic agents.

Flammability and Explosibility

Not classified

1-(2-Hydroxyethyl)piperazine Preparation Products And Raw materials

Raw materials

PIPERAZINE HEXAHYDRATE N,N-Bis(2-hydroxyethyl)ethylenediamine 4-(2-HYDROXYETHYL)-PIPERAZIN-2-ONE Nornitrogen mustard TERT-BUTYL 4-(2-HYDROXYETHYL)PIPERAZINE-1-CARBOXYLATE

1-Allyl-4-(2-hydroxyethyl)-piperazine 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE ETHYLENE OXIDE 2-Bromoethanol Piperazine

GLYCOLALDEHYDE Triethanolamine N-(2-Hydroxyethyl)glycine

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Preparation Products

ACETOPHENAZINE MALEATE (200 MG) Manidipine 1-(2-Hydroxyethyl)-4-methylpiperazine Triethylenediamine 1-Ethylpiperazine

2-(4-Benzhydrylpiperazino)ethyl acetoacetate

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1-(2-Hydroxyethyl)piperazine Suppliers

Global( 628)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan Hainuowei Technology Co. Ltd.	13708085536 13708085536	hanovichem@163.com	China	3268	56
Shandong Mingde Biotechnology Co., Ltd	15564477061	1397986535@qq.com	China	272	58
Wuhan xinyangruihe Chemical Technology Co., Ltd.	153-07155313 15307155313	2274366233@qq.com	China	6656	58
Tianjin Realet Chemical Technology Co.,Ltd.	022-58788819 13602056505	linlin@realetchem.com	China	50	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81

Supplier	Advantage
Sichuan Hainuowei Technology Co. Ltd.	56
Shandong Mingde Biotechnology Co., Ltd	58
Wuhan xinyangruihe Chemical Technology Co., Ltd.	58
Tianjin Realet Chemical Technology Co.,Ltd.	55
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
future industrial shanghai co., ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81

1-(2-Hydroxyethyl)piperazine: Polyfunctional Piperazine Derivative
1-(2-Hydroxyethyl)piperazine contains secondary amine, widely used as epoxy curing agent, pharmaceutical and pesticide interme....
Jun 30,2026

View Lastest Price from 1-(2-Hydroxyethyl)piperazine manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-12	N-(2-Hydroxyethyl)piperazine 103-76-4		0.99		RongNa Biotechnology Co.,Ltd
2026-09-11	N-(2-Hydroxyethyl)piperazine 103-76-4	1000kg	99	20000mt	Gansu Jinyuantai New Material Co., Ltd.
2026-09-11	N-(2-Hydroxyethyl)piperazine 103-76-4	1000kg	99	20000mt	Anhui Royal Chemical Co., Ltd.

N-(2-Hydroxyethyl)piperazine
103-76-4
0.99
RongNa Biotechnology Co.,Ltd

N-(2-Hydroxyethyl)piperazine
103-76-4
$0.00
99
Gansu Jinyuantai New Material Co., Ltd.

N-(2-Hydroxyethyl)piperazine
103-76-4
$0.00
99
Anhui Royal Chemical Co., Ltd.

1-(2-Hydroxyethyl)piperazine Spectrum

1-(2-Hydroxyethyl)piperazine(103-76-4)MS 1-(2-Hydroxyethyl)piperazine(103-76-4)¹HNMR 1-(2-Hydroxyethyl)piperazine(103-76-4)¹³CNMR 1-(2-Hydroxyethyl)piperazine(103-76-4)IR1 1-(2-Hydroxyethyl)piperazine(103-76-4)IR2 1-(2-Hydroxyethyl)piperazine(103-76-4)Raman

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HEPES HEPPS 1,4-Bis(2-hydroxyethyl)piperazine

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2-(Piperazin-1-yl)ethan-1-ol, 1-Hydroxy-2-(piperazin-1-yl)ethane NSC 26884 NSC 38969 NSC 60706 1-Piperazineethanol ,98% 1-(2-Hydroxyethyl)piperazine,2-Piperazinoethanol, Piperazine-1-ethanol N-(2-Hydroxyethyl)pi N-(2-Hydroxyethyl)piperazine, 98.5% 100GR N-(2-Hydroxyethyl)piperazine, 98.5% 5GR N-(2-Hydroxyethyl)piperazine (1-Piperazineethanol) N- (2- hydroxyethyl) piperazine (hydroxyethyl piperazine) N-(2-Hydroxyethyl)piperazine, 97+% 2-(1-PIPERAZINYL)ETHANOL FOR SYNTHESIS 2-(N-Piperazino)ethanol 1-(2-Hydroxyethyl)piperazine Vetec(TM) reagent grade, 98% N-(2-Hydroxyethyl) piperazine 1-(2-Hydroxyethyl) piperazine N-(2-Hydroxyethyl)piperazine≥ 99.9% 1-(2-Hydroxyethyl)piperazine (HEP) CAS No 103-76-4 2-PIPERAZINBETHANOL 2-HYDROXYETHYLPIPERAZINE 2-(1-PIPERAZINYL)ETHANOL 2-(1-PIPERAZYL)ETHANOL 1-(2-HYDROXYETHYL)PIPERAZINE 1-(2-HYDROXYETHYL)PIPERIZINE AKOS BBS-00003648 LABOTEST-BB LTBB000751 2-(1-Piperazino)ethanol 1-(2-Hydroxyethyl)Piperazine,98% N-(2-Hydroxyethyl)piperazine, 98.50% 1-(2-Hydroxyethyl)-piperazine (for CETRIZINE) 1-(2-Hydroxyethyl)piperazine 97% Piperazinoethanol 2-Piperazinoethanol, Piperazine-1-ethanol N-(2-Hydroxyethyl)piperazine, 98.5% 2-(Piperazine-1-yl)ethanol 1-HYDROXYETHYL PIPERAZINE 1-(2-HYDROXYETHYL)PIPERAZINE / 2-(1-PIPERAZINO)ETHANOL (N-(2-Hydroxyethyl)ethylendiaminetriacetic acid) Buclizine Impurity 3 PIPERAZINE ETHANOL PIPERAZINE-1-ETHANOL N-B-HYDROXYETHYLPIPERAZINE N-BETA-HYDROXYETHYLPIPERAZINE TIMTEC-BB SBB004225 1-Hydroxy-2-(piperazin-1-yl)ethane 1-Piperazinethanol 2-(1-piperazinyl)-ethano 4-(2-Hydroxyethyl)piperazine Ethanol, 2-(1-piperazinyl)- Hydroxyethylpiperazine (beta-Hydroxyethyl)piperazine 1-(beta-Hydroxyethyl)piperazine USAF do-22 usafdo-22 1-(2-Hydroxyethyl)piperazine, 98%, for synthesis 1-(2-Hydroxyethyl)piperazine> N-(2-Hydroxyethyl)piperazin 1‐(2‐Hydroxyethyl)piperazine?(HEP)

1-(2-Hydroxyethyl)piperazine

1-(2-Hydroxyethyl)piperazine Properties

SAFETY

Risk and Safety Statements

1-(2-Hydroxyethyl)piperazine price More Price(84)

1-(2-Hydroxyethyl)piperazine Chemical Properties,Uses,Production

Description

Chemical Properties

Uses

Uses

Flammability and Explosibility

1-(2-Hydroxyethyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

1-(2-Hydroxyethyl)piperazine Suppliers

Related articles

View Lastest Price from 1-(2-Hydroxyethyl)piperazine manufacturers

1-(2-Hydroxyethyl)piperazine Spectrum

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