- BENZAMIDINE
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- $15.00 / 1KG
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2021-07-13
- CAS:618-39-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- BENZAMIDINE
-
- $15.00 / 1KG
-
2021-07-10
- CAS:618-39-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- BENZAMIDINE
-
- $1.00 / 1kg
-
2019-07-06
- CAS:618-39-3
- Min. Order: 1kg
- Purity: 95%-99%
- Supply Ability: 100kg
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| | BENZAMIDINE Basic information |
| | BENZAMIDINE Chemical Properties |
| Melting point | 65-70 °C | | Boiling point | 208.5±23.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | powder or crystals | | pka | 11.90±0.40(Predicted) | | color | White to Off-White | | BRN | 606020 | | InChI | InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9) | | InChIKey | PXXJHWLDUBFPOL-UHFFFAOYSA-N | | SMILES | C1(C(N)=N)=CC=CC=C1 |
| Hazard Codes | Xn | | Risk Statements | 22-36 | | Safety Statements | 26 | | WGK Germany | 3 | | F | 9-23 | | HS Code | 29299000 | | Storage Class | 11 - Combustible Solids |
| | BENZAMIDINE Usage And Synthesis |
| Uses | Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor). | | Definition | ChEBI: Benzamidine is a carboxamidine that is benzene carrying an amidino group. It has a role as a serine protease inhibitor. It is a member of benzenes and a carboxamidine. It is functionally related to a benzoic acid. It is a conjugate base of a benzamidine(1+). | | Synthesis Reference(s) | The Journal of Organic Chemistry, 27, p. 1255, 1962 DOI: 10.1021/jo01051a033
Tetrahedron Letters, 31, p. 1969, 1990 DOI: 10.1016/S0040-4039(00)88891-7 | | Biochem/physiol Actions | Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH. | | Purification Methods | It is liberated from its hydrochloride chloride (below) by treatment with 5M NaOH, extracted into diethyl ether, dried (Na2SO4) and sublimed in vacuo.[Beilstein 9 H 280, 9 I 123, 9 II 199, 9 1264, 9 IV 898.] |
| | BENZAMIDINE Preparation Products And Raw materials |
| Preparation Products | 3,5,6-Triphenyl-1,2,4-triazine-->2-Phenylpyrimidine-5-carboxaldehyde-->2,4,6-TRIPHENYL-S-TRIAZINE-->Ethyl 4-nitrophenylacetate-->2,4,5-Triphenylimidazole-->2-(2-phenyl-1H-imidazol-4-yl)acetonitrile-->6-Bromo-3-phenyl-4H-1,2,4-benzothiadiazine-1,1-dione |
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