TROPONE
- CAS No.
- 539-80-0
- Chemical Name:
- TROPONE
- Synonyms
- cyclohepta-2,4,6-trien-1-one;2,4,6-CYCLOHEPTATRIEN-1-ONE;cyclohepta-2,4,6-trienone;Tropon;TROPONE;Tropone,97%;Cycloheptatrienone;cycloheptyltrieneone;LABOTEST-BB LT00233179;2,4,6-CYCLOHEPTATRIENONE
- CBNumber:
- CB8724528
- Molecular Formula:
- C7H6O
- Molecular Weight:
- 106.12
- MDL Number:
- MFCD00014331
- MOL File:
- 539-80-0.mol
- MSDS File:
- SDS
| Melting point | -7°C |
|---|---|
| Boiling point | 113 °C/15 mmHg (lit.) |
| Density | 1.094 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >110°C |
| storage temp. | -20°C |
| solubility | sol ether, dioxane, acetone, benzene, toluene, xylene, MeCN, CCl4; miscible with water. |
| form | Liquid |
| color | very deep brown |
| BRN | 1902335 |
| InChI | 1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H |
| InChIKey | QVWDCTQRORVHHT-UHFFFAOYSA-N |
| SMILES | O=C1C=CC=CC=C1 |
| FDA UNII | CO48X7SUFH |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
TROPONE price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 252832 | Tropone 97% | 539-80-0 | 1g | $94.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 252832 | Tropone 97% | 539-80-0 | 5g | $235 | 2026-04-30 | Buy |
| TCI Chemical | T4305 | Tropone min. 98.0 % | 539-80-0 | 200MG | $123 | 2026-04-30 | Buy |
| TCI Chemical | T4305 | Tropone min. 98.0 % | 539-80-0 | 1G | $369 | 2026-04-30 | Buy |
| Biosynth | FC59201 | 2,4,6-Cycloheptatrien-1-one | 539-80-0 | 1g | $900 | 2026-06-04 | Buy |
TROPONE Chemical Properties, Uses, Production
Uses
Tropone has been used in synthesis of:
- bicyclic δ-lactones via heterocyclic carbine-catalyzed [8+3] annulation pathway
- 6,7-benzobicyclo [3.2.2] nona-3,6,8-trien-2-one via thermal addition to bezyne
Application
Tropone can be used to prepare the synthon of cycloheptadiene-1-one; it is used as the basis for the synthesis of cycloheptadiene compounds, fluorene compounds, polycyclic compounds, and natural products.
Preparation
2,4,6-cycloheptatrien-1-one (1) is a functionalized conjugated carbocyclic compound with diversified reactivity. The most popular and simple method of preparation involves oxidation of 1,3,5- Cycloheptatriene with Selenium(IV) Oxide-KH2PO4. Several other procedures have also been developed, among which electrooxidation of cycloheptatrienes and α-pyrone ring expansion via high-pressure cycloaddition of cyclopropenone acetals can be considered general methods of synthesis of tropones.
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 5442, 1956 DOI: 10.1021/ja01601a077
The Journal of Organic Chemistry, 29, p. 960, 1964
Organic Syntheses, Coll. Vol. 9, p. 396, 1998
General Description
Metal-catalyzed [6+3] cycloaddition of tropone with azomethine ylides has been reported.
TROPONE Preparation Products And Raw materials
TROPONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Guangzhou Jhd Chemical Reagent Co., Ltd. | 020-84383047 | sales@jhd.com.cn | China | 9177 | 65 |
