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4-Methyl-3-nitropyridine

4-Methyl-3-nitropyridine Structure
4-Methyl-3-nitropyridine structure
CAS No.
5832-44-0
Chemical Name:
4-Methyl-3-nitropyridine
Synonyms
3-nitro-4-picoline;4-METHYL-3-NITROPYRIDINE;3-Nitro-4-methylpyridine;Methyl-3-nitropyridine,4-;pyridine, 4-Methyl-3-nitro-;4-Methyl-3-nitropyridine>4-Methyl-3-nitropyridine 97%;4-Methyl-3-nitropyridine,98%;Pyridine, 4-methyl-3-nitro- (9CI);4-Methyl-3-nitropyridine ISO 9001：2015 REACH
CBNumber:
CB8769909
Molecular Formula:
C6H6N2O2
Molecular Weight:
138.12
MDL Number:
MFCD00051829
MOL File:
5832-44-0.mol
MSDS File:
SDS
Last updated:2026-05-28 05:50:31
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4-Methyl-3-nitropyridine Properties

Melting point 24-28 °C
Boiling point 238 °C
Density 1.228 g/mL at 25 °C
refractive index n20/D 1.549
Flash point 227 °F
storage temp. Inert atmosphere,Room Temperature
pka 1.87±0.18(Predicted)
form powder to lump to clear liquid
color White or Colorless to Yellow
BRN 118796
InChI InChI=1S/C6H6N2O2/c1-5-2-3-7-4-6(5)8(9)10/h2-4H,1H3
InChIKey JLNRJMGYBKMDGI-UHFFFAOYSA-N
SMILES C1=NC=CC(C)=C1[N+]([O-])=O
CAS DataBase Reference 5832-44-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn,T,Xi
Risk Statements  22-37/38-41-36/37/38
Safety Statements  26-39-36
RIDADR  2810
WGK Germany  3
Hazard Note  Harmful
HazardClass  6.1
PackingGroup  III
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
1
3 0

4-Methyl-3-nitropyridine price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 532592 4-Methyl-3-nitropyridine 97% 5832-44-0 1g $52.7 2023-06-20 Buy
Sigma-Aldrich 532592 4-Methyl-3-nitropyridine 97% 5832-44-0 5g $219 2023-06-20 Buy
TCI Chemical M2353 4-Methyl-3-nitropyridine >97.0%(GC) 5832-44-0 1g $56 2023-06-20 Buy
TCI Chemical M2353 4-Methyl-3-nitropyridine >97.0%(GC) 5832-44-0 5g $188 2023-06-20 Buy
Usbiological 233342 4-Methyl-3-nitropyridine hydrochloride 5832-44-0 1g $229 2026-06-03 Buy
Product number Packaging Price Buy
532592 1g $52.7 Buy
532592 5g $219 Buy
M2353 1g $56 Buy
M2353 5g $188 Buy
233342 1g $229 Buy

4-Methyl-3-nitropyridine Chemical Properties, Uses, Production

Chemical Properties

Deliquescent cryst

Uses

4-Methyl-3-nitropyridine may be used as a starting material in the synthesis of ethyl 6-azaindole-2-carboxylate and also 3-substituted azaindoles.

Uses

4-METHYL-3-NITROPYRIDINE is a useful research chemical.

General Description

4-Methyl-3-nitropyridine, a substituted nitropyridine, can be prepared by the malonation of 4-methoxy-3-nitropyridine with sodium diethyl malonate.

Synthesis

4-Methylpyridine

108-89-4

4-Methyl-3-nitropyridine

5832-44-0

The general procedure for synthesizing 3-nitro-4-methylpyridine from 4-methylpyridine is as follows:1) In step 1) of Example 1, prepare a reaction solution by adding 60 g of nitrogen pentoxide solid to 300 g of liquid sulfur dioxide at -30° C. and stirring sufficiently until completely dissolved.2) Dissolve 30 g of 4-methylpyridine in 120 g of liquid sulfur dioxide and maintain the temperature at -30° C.3 ) Slowly drop the reaction solution into 300 g of ice water for 5 minutes. ) Slowly add the nitrogen pentoxide-sulfur dioxide solution prepared in step 1) dropwise to the 4-methylpyridine solution, and react for 5 min. 4) Slowly pour the reaction solution into 300 g of ice water, and hydrolyze thoroughly. 5) Adjust the pH of the hydrolyzed solution to 8-9 using sodium carbonate. 6) Add 290 g of toluene for two extractions, and combine the extracts. 7) Remove the solvent by vacuum distillation to obtain 39 g of 3- Nitro-4-methylpyridine. The purity of the product was 99.0% by gas chromatography.

References

[1] Organic and Biomolecular Chemistry, 2005, vol. 3, # 3, p. 538 - 541
[2] Acta Chemica Scandinavica, 1994, vol. 48, # 12, p. 1001 - 1006
[3] Acta Chemica Scandinavica, 1994, vol. 48, # 2, p. 181 - 182
[4] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995, # 6, p. 1211 - 1216
[5] Acta Chemica Scandinavica, 1996, vol. 50, # 6, p. 556 - 557

4-Methyl-3-nitropyridine Preparation Products And Raw materials

Raw materials

4-Methylpyridine Sodium sulfate Trifluoroacetic acid Trifluoroacetic anhydride Ethyl acetate
Nitric acid Dichloromethane Sodium hydroxide Petroleum ether Sodium metabisulfite
Potassium nitrate

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Preparation Products

3-Nitroisonicotinaldehyde ethyl 3-(3-nitropyridin-4-yl)-2-oxopropanoate N,N-Dimethyl-N-[(E)-2-(3-nitropyridin-4-yl)vinyl]amine

4-Methyl-3-nitropyridine Suppliers

Global Suppliers ( 258)
Supplier Tel Email Country ProdList Advantage
Shijiazhuang suchen Chemical Technology Co. LTD 186-33933494 18032288352 1130239@qq.com China 192 60
Hunan Caiya Biological Technology Co., Ltd 15580017485 2036676503@qq.com China 91 58
TAIZHOU DKD CHEMICAL CO., LTD. 0576-58336633 18658336633 yf.chen@tzdkdchem.com China 117 58
Jiangyin Jufeng Biotechnology Co., Ltd 0519-89891966 13906113265 986329407@qq.com China 56 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
Shijiazhuang suchen Chemical Technology Co. LTD 60
Hunan Caiya Biological Technology Co., Ltd 58
TAIZHOU DKD CHEMICAL CO., LTD. 58
Jiangyin Jufeng Biotechnology Co., Ltd 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 4-Methyl-3-nitropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methyl-3-nitropyridine pictures 2026-08-20 4-Methyl-3-nitropyridine
5832-44-0
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
4-Methyl-3-nitropyridine pictures 2025-04-04 4-Methyl-3-nitropyridine
5832-44-0
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
4-Methyl-3-nitropyridine pictures 2022-11-09 4-Methyl-3-nitropyridine
5832-44-0
 25kg 99% 20 tons TAIZHOU DKD CHEMICAL CO., LTD.

4-Methyl-3-nitropyridine Spectrum

4-Methyl-3-nitropyridine(5832-44-0)1HNMR

5832-44-0 (4-Methyl-3-nitropyridine) Related Search:

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Parathion-methyl nitrotoluene 2-AMINO-3-NITRO-4-PICOLINE (2-AMINO-4-METHYL-3-NITROPYRIDINE)

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4-METHYL-3-NITROPYRIDINE pyridine, 4-Methyl-3-nitro- 3-Nitro-4-methylpyridine 3-nitro-4-picoline Pyridine, 4-methyl-3-nitro- (9CI) Methyl-3-nitropyridine,4- 4-Methyl-3-nitropyridine,98% 4-Methyl-3-nitropyridine 97% 4-Methyl-3-nitropyridine> 4-Methyl-3-nitropyridine ISO 9001：2015 REACH 5832-44-0 5932-44-0 Building Blocks Pyridines Heterocyclic Building Blocks C6 Heterocycle-Pyridine series NITRO Pyridine series Pyridine Heterocyclic Building Blocks Pyridines C6