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2,6-DIMETHYL-4-METHOXYBENZOIC ACID

2,6-DIMETHYL-4-METHOXYBENZOIC ACID structure

CAS No.: 37934-89-7

Chemical Name:: 2,6-DIMETHYL-4-METHOXYBENZOIC ACID

Synonyms: 4-METHOXY-2,6-DIMETHYLBENZOIC ACID;2,6-DIMETHYL-4-METHOXYBENZOIC ACID;Benzoic acid, 4-?methoxy-?2,?6-?dimethyl-

CBNumber:: CB8780795

Molecular Formula:: C10H12O3

Molecular Weight:: 180.2

MDL Number:: MFCD01194287

MOL File:: 37934-89-7.mol

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
2,6-Dimethyl-4-methoxybenzoicAcid	D460178	100mg	$75
2,6-DIMETHYL-4-METHOXYBENZOIC ACID 95.00%	CHM0303997	5MG	$501.62
2,6-Dimethyl-4-methoxybenzoicacid	37934897	250mg	$680
2,6-Dimethyl-4-methoxybenzoicacid 97%	23026	100g	$847
2,6-Dimethyl-4-methoxybenzoicacid	37934897	500mg	$980
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2,6-DIMETHYL-4-METHOXYBENZOIC ACID Properties

Melting point	144.5-145 °C
Boiling point	310.0±37.0 °C(Predicted)
Density	1.136±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	3.98±0.37(Predicted)
Appearance	White to yellow Solid

SAFETY

Risk and Safety Statements

HS Code	2918999090

2,6-DIMETHYL-4-METHOXYBENZOIC ACID price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D460178	2,6-Dimethyl-4-methoxybenzoicAcid	37934-89-7	100mg	$75	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0303997	2,6-DIMETHYL-4-METHOXYBENZOIC ACID 95.00%	37934-89-7	5MG	$501.62	2021-12-16	Buy
Alichem	37934897	2,6-Dimethyl-4-methoxybenzoicacid	37934-89-7	250mg	$680	2021-12-16	Buy
AOBChem	23026	2,6-Dimethyl-4-methoxybenzoicacid 97%	37934-89-7	100g	$847	2021-12-16	Buy
Alichem	37934897	2,6-Dimethyl-4-methoxybenzoicacid	37934-89-7	500mg	$980	2021-12-16	Buy

Product number	Packaging	Price	Buy
D460178	100mg	$75	Buy
CHM0303997	5MG	$501.62	Buy
37934897	250mg	$680	Buy
23026	100g	$847	Buy
37934897	500mg	$980	Buy

2,6-DIMETHYL-4-METHOXYBENZOIC ACID Chemical Properties,Uses,Production

Synthesis

124-38-9

6267-34-1

37934-89-7

General procedure for the synthesis of 2,6-dimethyl-4-methoxybenzoic acid from carbon dioxide and 4-bromo-3,5-dimethylanisole: 4-bromo-3,5-dimethylanisole (3.38 g, 15.79 mmol) was dissolved directly in 100 mL of anhydrous tetrahydrofuran (THF) without further purification. The reaction mixture was cooled to -78 °C under argon protection, followed by slow dropwise addition of n-butyllithium (1.6 M hexane solution, 9.9 mL, 15.8 mmol) over 15 min. After the dropwise addition was completed, the reaction mixture continued to be stirred at -78 °C for 15 min. Subsequently, a small amount of dry ice was added to the reaction system and stirring was continued at -78 °C for 20 minutes. The cooling bath was removed and the reaction mixture was allowed to gradually warm up to room temperature while stirring was continued until the release of carbon dioxide gas ceased. The reaction mixture was poured into 100 mL of ice water and acidified with 6N hydrochloric acid. The organic layer was separated and the aqueous phase was extracted with ethyl acetate (EtOAc). All organic phases were combined, washed sequentially with saturated saline and deionized water, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. 2,6-Dimethyl-4-methoxybenzoic acid was finally obtained as a white solid (2.7 g, 95% yield). Mass spectrometry analysis showed that the (M+H)+ peak was located at m/z 181.

References

[1] Patent: US2005/84506, 2005, A1. Location in patent: Page/Page column 97

2,6-DIMETHYL-4-METHOXYBENZOIC ACID Preparation Products And Raw materials

Raw materials

Carbon dioxide 4-BROMO-3,5-DIMETHYLANISOLE Water Tetrahydrofuran Hydrochloric acid

petroleum ether 40 60 n-Butyllithium

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Preparation Products

4-methoxy-2,6-dimethyl-aniline 4-Hydroxy-2,6-dimethylbenzoic acid

2,6-DIMETHYL-4-METHOXYBENZOIC ACID Suppliers

Global( 58)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10035	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14360	58
Changzhou Anxuan Chemical Co., Ltd	+86-0519-89882563 +86-18961279162	andy@anxuanchem.com	China	4327	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19632	58

Supplier	Advantage
Changzhou Ansciep Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Fuxin Pharmaceutical	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Changzhou Anxuan Chemical Co., Ltd	58
Aromsyn Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aceschem Inc.	58

2,6-DIMETHYL-4-METHOXYBENZOIC ACID Spectrum

2,6-DIMETHYL-4-METHOXYBENZOIC ACID(37934-89-7)¹HNMR

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2,6-DIMETHYL-4-METHOXYBENZOIC ACID 4-METHOXY-2,6-DIMETHYLBENZOIC ACID Benzoic acid, 4-?methoxy-?2,?6-?dimethyl- 37934-89-7