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ChemicalBook >> CAS DataBase List >>2,6-Dimethyl-4-methoxybenzoic acid

2,6-Dimethyl-4-methoxybenzoic acid

2,6-Dimethyl-4-methoxybenzoic acid Structure
2,6-Dimethyl-4-methoxybenzoic acid structure
CAS No.
37934-89-7
Chemical Name:
2,6-Dimethyl-4-methoxybenzoic acid
Synonyms
4-METHOXY-2,6-DIMETHYLBENZOIC ACID;2,6-Dimethyl-4-methoxybenzoic acid;Benzoic acid, 4-?methoxy-?2,?6-?dimethyl-
CBNumber:
CB8780795
Molecular Formula:
C10H12O3
Molecular Weight:
180.2
MDL Number:
MFCD01194287
MOL File:
37934-89-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:52
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2,6-Dimethyl-4-methoxybenzoic acid Properties

Melting point 144.5-145 °C
Boiling point 310.0±37.0 °C(Predicted)
Density 1.136±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.98±0.37(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2918999090

2,6-Dimethyl-4-methoxybenzoic acid price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth MBA93489 2,6-Dimethyl-4-methoxybenzoic acid 37934-89-7 10g $472 2026-06-04 Buy
Biosynth MBA93489 2,6-Dimethyl-4-methoxybenzoic acid 37934-89-7 100g $2360 2026-06-04 Buy
Apolloscientific OR919035 2,6-Dimethyl-4-methoxybenzoic acid 95% 37934-89-7 1g $77 2026-06-04 Buy
Activate Scientific AS47674 2,6-Dimethyl-4-methoxybenzoic acid 98% 37934-89-7 1g $42 2026-06-04 Buy
Activate Scientific AS47674 2,6-Dimethyl-4-methoxybenzoic acid 98% 37934-89-7 5g $144 2026-06-04 Buy
Product number Packaging Price Buy
MBA93489 10g $472 Buy
MBA93489 100g $2360 Buy
OR919035 1g $77 Buy
AS47674 1g $42 Buy
AS47674 5g $144 Buy

2,6-Dimethyl-4-methoxybenzoic acid Chemical Properties, Uses, Production

Synthesis

Carbon dioxide

124-38-9

4-BROMO-3,5-DIMETHYLANISOLE

6267-34-1

2,6-DIMETHYL-4-METHOXYBENZOIC ACID

37934-89-7

General procedure for the synthesis of 2,6-dimethyl-4-methoxybenzoic acid from carbon dioxide and 4-bromo-3,5-dimethylanisole: 4-bromo-3,5-dimethylanisole (3.38 g, 15.79 mmol) was dissolved directly in 100 mL of anhydrous tetrahydrofuran (THF) without further purification. The reaction mixture was cooled to -78 °C under argon protection, followed by slow dropwise addition of n-butyllithium (1.6 M hexane solution, 9.9 mL, 15.8 mmol) over 15 min. After the dropwise addition was completed, the reaction mixture continued to be stirred at -78 °C for 15 min. Subsequently, a small amount of dry ice was added to the reaction system and stirring was continued at -78 °C for 20 minutes. The cooling bath was removed and the reaction mixture was allowed to gradually warm up to room temperature while stirring was continued until the release of carbon dioxide gas ceased. The reaction mixture was poured into 100 mL of ice water and acidified with 6N hydrochloric acid. The organic layer was separated and the aqueous phase was extracted with ethyl acetate (EtOAc). All organic phases were combined, washed sequentially with saturated saline and deionized water, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. 2,6-Dimethyl-4-methoxybenzoic acid was finally obtained as a white solid (2.7 g, 95% yield). Mass spectrometry analysis showed that the (M+H)+ peak was located at m/z 181.

References

[1] Patent: US2005/84506, 2005, A1. Location in patent: Page/Page column 97

2,6-Dimethyl-4-methoxybenzoic acid Preparation Products And Raw materials

Raw materials

Carbon dioxide 4-Bromo-3,5-dimethylanisole Water Tetrahydrofuran Hydrochloric acid
petroleum ether 40 60 n-Butyllithium

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Preparation Products

4-methoxy-2,6-dimethyl-aniline 4-Hydroxy-2,6-dimethylbenzoic acid

2,6-Dimethyl-4-methoxybenzoic acid Suppliers

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
Beijing Hechemist Technology CO.,LTD 18511709189; sales@hechemist.com China 2835 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
AAB-PHARMA LIMITED 025-66800956 18800000000 sales@njdmchem.com China 4200 50
LinkChem Technology Co., Ltd. 021-58950110 13124863828 sales@linkchem.cn China 2996 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Mirro Chemical Co.,Ltd. 0086-15313090952 China 2354 58
Supplier Advantage
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Shanghai Raise Chemical Technology Co.,Ltd 55
Changzhou Anxuan Chemical, Co., Ltd. 58
Beijing Hechemist Technology CO.,LTD 58
Amadis Chemical Company Limited 58
AAB-PHARMA LIMITED 50
LinkChem Technology Co., Ltd. 58
Wuxi AppTec 58
Mirro Chemical Co.,Ltd. 58

2,6-Dimethyl-4-methoxybenzoic acid Spectrum

2,6-DIMETHYL-4-METHOXYBENZOIC ACID(37934-89-7)1HNMR

37934-89-7 (2,6-Dimethyl-4-methoxybenzoic acid) Related Search:

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Benzoic acid, 4-?methoxy-?2,?6-?dimethyl- 4-METHOXY-2,6-DIMETHYLBENZOIC ACID 2,6-Dimethyl-4-methoxybenzoic acid 37934-89-7