thenalidine
- CAS No.
- 86-12-4
- Chemical Name:
- thenalidine
- Synonyms
- Thenalidin;Sandostene;Thenaldine;thenalidine;Thenophenopiperidine;thenalidine USP/EP/BP;1-Methyl-4-[phenyl(2-thienylmethyl)amino]piperidine;4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)-
- CBNumber:
- CB8914477
- Molecular Formula:
- C17H22N2S
- Molecular Weight:
- 286.43
- MDL Number:
- MFCD00865681
- MOL File:
- 86-12-4.mol
- MSDS File:
- SDS
| Melting point | 95-97° |
|---|---|
| Boiling point | bp0.02 158-160° |
| Density | 1.140±0.06 g/cm3(Predicted) |
| pka | pKa 3.36±0.06(H2O t undefined I = 0.30 (NaCl)) (Uncertain);8.39±0.07(H2O t undefined I = 0.30 (NaCl)) (Uncertain) |
| FDA UNII | 6U94N2D00F |
| ATC code | D04AA03,R06AX03,R06AX53 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
thenalidine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA01EEY0 | 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine ≥95% | 86-12-4 | 1mg | $200 | 2026-05-30 | Buy |
| aablocks | AA01EEY0 | 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine ≥95% | 86-12-4 | 5mg | $520 | 2026-05-30 | Buy |
| aablocks | AA01EEY0 | 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine ≥95% | 86-12-4 | 10mg | $800 | 2026-05-30 | Buy |
| aablocks | AA01EEY0 | 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine ≥95% | 86-12-4 | 25mg | $1400 | 2026-05-30 | Buy |
| aablocks | AA01EEY0 | 1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine ≥95% | 86-12-4 | 50mg | $2000 | 2026-05-30 | Buy |
thenalidine Chemical Properties, Uses, Production
Uses
Thenalidine is an antihistamine that has anticholinergic properties which is used as an antipruritic drugs.
Definition
ChEBI: Thenalidine is a dialkylarylamine and a tertiary amino compound.
brand name
Sanbosten.
World Health Organization (WHO)
Thenalidine, a piperidine antihistamine, was introduced in 1953 for the management of dermatologic and allergic conditions. By 1958 its use had been associated with cases of severe neutropenia, two of them fatal, which led to its withdrawal in the United States of America and subsequently in the United Kingdom. Over the next fifteen years, continued reports of its association with cases of neutropenia resulted in further withdrawals in many countries. It is apparently still available, however, in some combination products.
Synthesis
Thenalidine is synthesized by alkylation of 1-methyl-4-phenylaminopiperidine with 2-chloromethyl thiophene .
thenalidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | sales@linyuepharm.com | China | 5731 | 55 |
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53736 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +86-13289823923 | 1090@dideu.com | China | 8651 | 58 |
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