guluronic acid
- CAS No.
- 15769-56-9
- Chemical Name:
- guluronic acid
- Synonyms
- G2013;guluronic acid;Einecs 239-860-9;Guluronic acid sodium salt;L-Guluronic Acid Sodium Salt/Guluronic acid;L-Monoguluronic Acid Sodium Salt, Mono-Guluronic Acid Sodium Salt
- CBNumber:
- CB8930228
- Molecular Formula:
- C6H10O7
- Molecular Weight:
- 194.14
- MDL Number:
- MFCD30533975
- MOL File:
- 15769-56-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 553.434±50.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.748±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pka | 3.65 |
| form | Solid |
| color | White to off-white |
| InChI | InChI=1S/C6H10O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h1-5,8-11H,(H,12,13)/t2-,3-,4+,5-/m0/s1 |
| InChIKey | IAJILQKETJEXLJ-KLVWXMOXSA-N |
| SMILES | O=C[C@@H]([C@@H]([C@H]([C@@H](C(O)=O)O)O)O)O |
| FDA UNII | 58QGW9MR67 |
guluronic acid Chemical Properties,Uses,Production
Description
Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living beings, this primary oxidation occurs with UDP-α-D-glucose (UDPG), not with the free sugar.
Glucuronic acid, like its precursor glucose, can exist as a linear (carboxo-)aldohexose (<1%), or as a cyclic hemiacetal (furanose or pyranose). Aldohexoses such as D-glucose are capable of forming two furanose forms (α and β) and two pyranose forms (α and β). By the Fischer convention, glucuronic acid has two stereoisomers (enantiomers), D- and L-glucuronic acid, depending on its configuration at C-5. Most physiological sugars are of the D-configuration. Due to ring closure, cyclic sugars have another asymmetric carbon atom (C-1), resulting in two more stereoisomers, named anomers. Depending on the configuration at C-1, there are two anomers of glucuronic acid, α- and β-form. In β-D-glucuronic acid the C-1 hydroxy group is on the same side of the pyranose ring as the carboxyl group. In the free sugar acid, the β-form is prevalent (~64%), whereas in the organism, the α-form UDP-α-D-glucuronic acid (UDPGA) predominates.
Uses
Guluronic acid (G2013), one of the organic building blocks of hyaluronic acid, is a nonsteroidal anti-inflammatory agent has favorable anti-inflammatory effect[1][2].
References
[1] Amaniampong PN, et al. Selective and Catalyst-free Oxidation of D-Glucose to D-Glucuronic acid induced by High-Frequency Ultrasound. Sci Rep. 2017;7:40650. Published 2017 Jan 13. DOI:10.1038/srep40650
[2] Nazeri S, et al. The safety and efficacy of Guluronic acid (G2013) in ankylosing spondylitis: A randomized controlled parallel clinical trial. Pharmacol Rep. 2019;71(3):393-398. DOI:10.1016/j.pharep.2019.02.002
guluronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| QINGDAO HEHAI BIOTECH CO.,LTD. | +86-0532-81926227 17667562617 | ann@marine-oligo.com | China | 96 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| Henan Aosman Biotechnology Co., LTD | 13761588971 17719817155 | 2366079749@qq.com | China | 3009 | 58 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 | chemwill_asia@126.com | CHINA | 23861 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Wuhan Topule | +86-02787215551 19945035818 | 2936752263@qq.com | China | 7985 | 58 |
View Lastest Price from guluronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Guluronic acid
15769-56-9
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Guluronic acid
15769-56-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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