5-Nitro-1-tetralone
- CAS No.
- 51114-73-9
- Chemical Name:
- 5-Nitro-1-tetralone
- Synonyms
- 5-NITRO-A-TETRALONE;5-Nitro-α-tetralone;5-Nitro-1-tetralone;5-Nitro-3,4-dihydronaphthalen-1(2H);5-nitro-3,4-dihydronaphthalen-1(2H)-one;3,4-dihydro-5-nitronaphthalen-1(2H)-one;5-Nitro-3,4-dihydro-2H-naphthalen-1-one;1(2H)-Naphthalenone, 3,4-dihydro-5-nitro-;5-nitro-1,2,3,4-tetrahydronaphthalen-1-one
- CBNumber:
- CB8948030
- Molecular Formula:
- C10H9NO3
- Molecular Weight:
- 191.18
- MDL Number:
- MFCD09751533
- MOL File:
- 51114-73-9.mol
- MSDS File:
- SDS
5-Nitro-1-tetralone price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | N53964 | 5-Nitro-3,4-dihydronaphthalen-1(2H)-one 95% | 51114-73-9 | 250mg | $54 | 2026-05-06 | Buy |
| Synthonix | N53964 | 5-Nitro-3,4-dihydronaphthalen-1(2H)-one 95% | 51114-73-9 | 1g | $58 | 2026-05-06 | Buy |
| Synthonix | N53964 | 5-Nitro-3,4-dihydronaphthalen-1(2H)-one 95% | 51114-73-9 | 5g | $60 | 2026-05-06 | Buy |
| Synthonix | N53964 | 5-Nitro-3,4-dihydronaphthalen-1(2H)-one 95% | 51114-73-9 | 25g | $180 | 2026-05-06 | Buy |
| Heterocyclics | JR-015185 | 5-Nitro-1-tetralone | 51114-73-9 | 25g | $265 | 2026-06-05 | Buy |
5-Nitro-1-tetralone Chemical Properties, Uses, Production
Synthesis Reference(s)
Journal of Medicinal Chemistry, 19, p. 472, 1976 DOI: 10.1021/jm00226a004
Synthesis
67857-97-0
51114-73-9
The general procedure for the synthesis of 5-nitro-α-tetralone from 4-(2-nitrophenyl)butyric acid was as follows: first, 1 g of 4-(2-nitrophenyl)butyric acid (NPBS, 4.78 mmol) and 18 g of trifluoromethanesulfonic acid (TFMS) were added to a 100 mL two-necked flask fitted with a reflux condenser and magnetic stirrer at 20 °C. Under stirring, the reaction mixture was placed in an oil bath preheated to 130 °C and stirred continuously at this temperature for 45 min. Upon completion of the reaction, the mixture was cooled and transferred to a microdistillation unit. Most of the excess TFMS was removed by distillation at 52 °C and 0.5 mbar.After distillation, the bottom residue contained 0.914 g of 5-nitro-3,4-dihydro-1(2H)-naphthalenone and 3.44 g of TFMS (as determined by the GC-ISTD/internal standard method) in 99.3% yield, with 100% conversion to NPBS and 99.3% selectivity.
References
[1] Patent: EP1369412, 2003, A1. Location in patent: Page 6
[2] Patent: US2003/176722, 2003, A1
5-Nitro-1-tetralone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Chainpharm Bio-medical Technology Co., Ltd. | +86-021-61727342 13611721451 | sales@chainpharm.com | China | 984 | 58 |
| Shanghai SunSyn Pharmaceutical Co., Ltd. | 021-18621020637 18621020637 | sales@sunsynpharma.com | China | 297 | 55 |
| Beijin Yangguang Furui Chemical co.,Ltd. | 010-57495520 13521095525 | zhw512@foxmail.com | China | 487 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Latest Price from 5-Nitro-1-tetralone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-04 | 5-Nitro-1-tetralone
51114-73-9
|
1g | 98%minHPLC | 100kgs/month | Shanghai Rlavie Technology Co ltd |
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- 5-Nitro-1-tetralone
51114-73-9
- 98%minHPLC
- Shanghai Rlavie Technology Co ltd
