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ChemicalBook >> CAS DataBase List >>3-(Methylamino)propanoic acid, N-BOC protected

3-(Methylamino)propanoic acid, N-BOC protected

3-(Methylamino)propanoic acid, N-BOC protected Structure
3-(Methylamino)propanoic acid, N-BOC protected structure
CAS No.
124072-61-3
Chemical Name:
3-(Methylamino)propanoic acid, N-BOC protected
Synonyms
N-Boc-N-Methyl-b-alanine;Boc-N-Me-β-Ala;Boc-N-Me-β-Ala-OH;Boc-N-Me-Beta-Ala;N-Boc-N-methyl-β-alanine;Boc-N-Methyl-beta-alanine;3-(MethylaMino)propanoic aci;N-BOC-3-(METHYLAMINO)PROPANOIC ACID;3-[(Boc)(methyl)amino]propionic Acid;3-(MethylaMino)propanoic acid, N-BOC
CBNumber:
CB8958013
Molecular Formula:
C9H17NO4
Molecular Weight:
203.24
MDL Number:
MFCD03490508
MOL File:
124072-61-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:14:37
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3-(Methylamino)propanoic acid, N-BOC protected Properties

Melting point 59-62
Boiling point 307.4±21.0 °C(Predicted)
Density 1.113±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 4.46±0.10(Predicted)
color Pale yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2922498590

3-(Methylamino)propanoic acid, N-BOC protected price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 263857 Boc-N-methyl-b-alanine 124072-61-3 250mg $305 2026-06-03 Buy
Usbiological 263857 Boc-N-methyl-b-alanine 124072-61-3 500mg $410 2026-06-03 Buy
Usbiological 263857 Boc-N-methyl-b-alanine 124072-61-3 1g $542 2026-06-03 Buy
Usbiological 263857 Boc-N-methyl-b-alanine 124072-61-3 2g $704 2026-06-03 Buy
Usbiological 263857 Boc-N-methyl-b-alanine 124072-61-3 5g $921 2026-06-03 Buy
Product number Packaging Price Buy
263857 250mg $305 Buy
263857 500mg $410 Buy
263857 1g $542 Buy
263857 2g $704 Buy
263857 5g $921 Buy

3-(Methylamino)propanoic acid, N-BOC protected Chemical Properties, Uses, Production

Synthesis

Boc-beta-alanine

3303-84-2

Iodomethane

74-88-4

3-(Methylamino)propanoic acid, N-BOC protected

124072-61-3

Step 1: Synthesis of 3-(tert-butoxycarbonyl(methyl)amino)propionic acid 1. a mineral oil suspension of 60% NaH (0.528 g, 13.21 mmol) was washed with hexane (2 x 10 mL) to remove the mineral oil. 2. The washed NaH was suspended in anhydrous THF (6 mL) and the mixture was cooled to 0°C. 3. A solution of Boc-β-alanine (1 g, 5.29 mmol) in anhydrous THF (6 mL) was slowly added with stirring. 4. After 5 min, anhydrous THF (6 mL) solution of iodomethane (0.823 mL, 13.21 mmol) was added dropwise. 5. The reaction mixture was stirred overnight at 0 °C to room temperature. 6. Upon completion of the reaction, the reaction was quenched with ice-cold deionized water (50 mL) and the mixture was washed with ether (25 mL). 7. Separate the aqueous layer and acidify to pH < 2 with concentrated aqueous hydrochloric acid (3 mL). 8. Extract the acidified aqueous layer with ethyl acetate (3 x 20 mL). 9. Combine the organic phases, dry with anhydrous sodium sulfate and concentrate under reduced pressure to afford the target product N-Boc-3-(methylamino)propionic acid (1.095 g, quantitative yield) as a yellow oil.

References

[1] Patent: US2014/66426, 2014, A1. Location in patent: Paragraph 0779
[2] Patent: WO2014/32801, 2014, A1. Location in patent: Page/Page column 157
[3] Journal of Medicinal Chemistry, 1994, vol. 37, # 11, p. 1562 - 1568
[4] Patent: US5428021, 1995, A

3-(Methylamino)propanoic acid, N-BOC protected Preparation Products And Raw materials

Raw materials

Boc-beta-alanine β-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, ethyl ester Iodomethane Sodium hydride Tetrahydrofuran
Mineral oil

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Preparation Products

3-(Methylamino)propanoic acid, N-BOC protected Suppliers

Global Suppliers ( 98)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Accela ChemBio Co.,Ltd. 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2348 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
Clearsynth Labs Limited 58
Amatek Scientific Co. Ltd. 55

View Latest Price from 3-(Methylamino)propanoic acid, N-BOC protected manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-((Tert-butoxycarbonyl)(methyl)amino)propanoic acid pictures 2026-10-21 3-((Tert-butoxycarbonyl)(methyl)amino)propanoic acid
124072-61-3
 $75.00-750.00 1KG 0.98 20 tons Zibo Hangyu Biotechnology Development Co., Ltd

3-(Methylamino)propanoic acid, N-BOC protected Spectrum

3-(Methylamino)propanoic acid, N-BOC protected(124072-61-3)1HNMR3-(Methylamino)propanoic acid, N-BOC protected(124072-61-3)FT-IR

124072-61-3 (3-(Methylamino)propanoic acid, N-BOC protected) Related Search:

N-Boc-N-methyl-(R)-2-allylglycine N-Boc-N-methyl-(S)-2-allylglycine (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid N-4-Boc-2-piperazinecarboxylic acid 4-Boc-1-Fmoc-2-piperazinecarboxylic acid
1-N-Boc-3-Azetidinecarboxylic acid N-Boc-3-carboethoxy-4-piperidone Methyl 4-Boc-piperazine-2-carboxylate N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid Boc-(S)-2-tetrahydroisoquinoline acetic acid
tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate 1-[(tert-Butyl)oxycarbonyl]-4-(2-chlorophenyl)pyrrolidine-3-carboxylic acid 1-Boc-piperidine-3-carboxylic acid Boc-(R)-2-tetrahydroisoquinoline acetic acid 4-Boc-2-morpholinecarboxylic acid
4-(4-Methoxy-phenyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 1-[(tert-Butyl)oxycarbonyl]-4-phenylpyrroline-3-carboxylic acid Boc-O-benzyl-L-beta-homohydroxyproline dicyclohexylamine salt

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3-(Methylamino)propanoic acid, N-BOC protected N-BOC-3-(METHYLAMINO)PROPANOIC ACID 3-(t-Butoxycarbonyl)methylamino-propionic acid N-(TERT-BUTOXYCARBONYL)-N-METHYL-BETA-ALANINE 3-[(TERT-BUTOXYCARBONYL)(METHYL)(AMINO)]PROPIONICACID 3-[methyl-[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid N-Boc-N-methyl-β-alanine 3-[(Boc)(methyl)amino]propionic Acid 3-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoic acid 3-(Methylamino)propanoic acid, N-BOC protected 98% N-t-butoxycarbonyl-N-methyl-β-alanine 3-[(tert-Butoxycarbonyl)(methyl)amino]propanoic acid 3-{[2-(tert-butoxy)-2-oxoethyl]aMino}propanoic acid 3-(MethylaMino)propanoic aci 3-[(tert-Butoxycarbonyl)(methyl)amino]propionic acid, N-(tert-Butoxycarbonyl)-N-methyl-beta-alanine 3-(MethylaMino)propanoic acid, N-BOC Boc-N-Methyl-beta-alanine Boc-N-Me-β-Ala-OH β-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine Boc-N-Me-Beta-Ala N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-β-alanine Boc-N-Me-β-Ala N-(tert-Butoxycarbonyl)-N-methyl-β-alanine N-Boc-N-Methyl-b-alanine 3-(N-Boc-N-methyl)aminopropionic acid 124072-61-3