S-Trityl-D-cysteine
- CAS No.
- 25840-82-8
- Chemical Name:
- S-Trityl-D-cysteine
- Synonyms
- D-Cys(Trt)-OH;S-Trityl-D-cysteine99%;(-)-S-Trityl-D-cysteine;(-)-S-Trityl-D-cysteine,98%;(-)-S-Trityl-D-cysteine,97%;S-Trityl-D-cysteine USP/EP/BP;S-(Triphenylmethyl)-D-cysteine;D-Cysteine, S-(triphenylmethyl)-;(S)-2-AMino-3-(tritylthio)propanoic acid;(2S)-2-amino-3-tritylsulfanylpropanoicaci
- CBNumber:
- CB91117670
- Molecular Formula:
- C22H21NO2S
- Molecular Weight:
- 363.47
- MDL Number:
- MFCD00236948
- MOL File:
- 25840-82-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| S-Trityl-D-cysteine 99+% | 241749 | 1g | $186 |
| (-)-S-Trityl-D-cysteine | T887925 | 500mg | $65 |
| (-)-S-Trityl-D-cysteine | T887925 | 100mg | $45 |
| -Trityl-D-cysteine ≥ 98% (HPLC) | 05952 | 25G | $45 |
| H-D-Cys(Trt)-OH 97% | AS112876 | 5G | $34 |
| More product size | |||
| Boiling point | 524.7±50.0 °C(Predicted) |
|---|---|
| Density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| pka | 2.22±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| optical activity | Consistent with structure |
| Water Solubility | Sparingly soluble in water 0.022 g/L 25°C. |
S-Trityl-D-cysteine price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 241749 | S-Trityl-D-cysteine 99+% | 25840-82-8 | 1g | $186 | 2021-12-16 | Buy |
| TRC | T887925 | (-)-S-Trityl-D-cysteine | 25840-82-8 | 500mg | $65 | 2021-12-16 | Buy |
| TRC | T887925 | (-)-S-Trityl-D-cysteine | 25840-82-8 | 100mg | $45 | 2021-12-16 | Buy |
| Chem-Impex | 05952 | -Trityl-D-cysteine ≥ 98% (HPLC) | 25840-82-8 | 25G | $45 | 2021-12-16 | Buy |
| Activate Scientific | AS112876 | H-D-Cys(Trt)-OH 97% | 25840-82-8 | 5G | $34 | 2021-12-16 | Buy |
S-Trityl-D-cysteine Chemical Properties,Uses,Production
Uses
(-)-S-Trityl-D-cysteine is used in medicine as intermediate. It inhibits the human mitotic kinesin Eg5.
Synthesis
76-84-6
921-01-7
2799-07-7
General procedure for the synthesis of S-triphenylmethyl-L-cysteine from triphenylmethanol and D-cysteine: D-cysteine (242.30 mg, 2.0 mmol) was placed in a single-necked flask, trifluoroacetic acid (TFA, 4 mL) was added and stirred at room temperature. Triphenylmethanol (520.68 mg, 2.0 mmol) was then added and the reaction continued to be stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C, anhydrous ether (30 mL) was added, and the pH was adjusted to 4-5 by slowly adding 4 N NaOH aqueous solution dropwise with stirring.Next, 10% saturated sodium acetate aqueous solution was added, and stirring was continued for 1 h to stabilize the pH at 5-6.The reaction mixture was filtered, and the filter cake was washed with anhydrous ether (30 mL × 2) to afford the white powdery product S Triphenylmethyl-L-cysteine (566.4 mg, yield: 77.90%).
References
[1] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0199; 0200; 0201; 0202
S-Trityl-D-cysteine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20284 | 58 |
