S-Trityl-D-cysteine
- CAS No.
- 25840-82-8
- Chemical Name:
- S-Trityl-D-cysteine
- Synonyms
- D-Cys(Trt)-OH;S-Trityl-D-cysteine99%;(-)-S-Trityl-D-cysteine;(-)-S-Trityl-D-cysteine,98%;(-)-S-Trityl-D-cysteine,97%;S-Trityl-D-cysteine USP/EP/BP;S-(Triphenylmethyl)-D-cysteine;D-Cysteine, S-(triphenylmethyl)-;(S)-2-AMino-3-(tritylthio)propanoic acid;(2S)-2-amino-3-tritylsulfanylpropanoicaci
- CBNumber:
- CB91117670
- Molecular Formula:
- C22H21NO2S
- Molecular Weight:
- 363.47
- MDL Number:
- MFCD00236948
- MOL File:
- 25840-82-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 524.7±50.0 °C(Predicted) |
|---|---|
| Density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| pka | 2.22±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| optical activity | Consistent with structure |
| Water Solubility | Sparingly soluble in water 0.022 g/L 25°C. |
S-Trityl-D-cysteine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 291148 | S-Trityl-D-cysteine Asreported | 25840-82-8 | 1g | $333 | 2026-06-03 | Buy |
| Usbiological | 291148 | S-Trityl-D-cysteine Asreported | 25840-82-8 | 2g | $456 | 2026-06-03 | Buy |
| Usbiological | 291148 | S-Trityl-D-cysteine Asreported | 25840-82-8 | 5g | $712 | 2026-06-03 | Buy |
| Usbiological | 291148 | S-Trityl-D-cysteine Asreported | 25840-82-8 | 10g | $977 | 2026-06-03 | Buy |
| Usbiological | 291148 | S-Trityl-D-cysteine Asreported | 25840-82-8 | 25g | $1356 | 2026-06-03 | Buy |
S-Trityl-D-cysteine Chemical Properties, Uses, Production
Uses
(-)-S-Trityl-D-cysteine is used in medicine as intermediate. It inhibits the human mitotic kinesin Eg5.
Synthesis
76-84-6
921-01-7
2799-07-7
General procedure for the synthesis of S-triphenylmethyl-L-cysteine from triphenylmethanol and D-cysteine: D-cysteine (242.30 mg, 2.0 mmol) was placed in a single-necked flask, trifluoroacetic acid (TFA, 4 mL) was added and stirred at room temperature. Triphenylmethanol (520.68 mg, 2.0 mmol) was then added and the reaction continued to be stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C, anhydrous ether (30 mL) was added, and the pH was adjusted to 4-5 by slowly adding 4 N NaOH aqueous solution dropwise with stirring.Next, 10% saturated sodium acetate aqueous solution was added, and stirring was continued for 1 h to stabilize the pH at 5-6.The reaction mixture was filtered, and the filter cake was washed with anhydrous ether (30 mL × 2) to afford the white powdery product S Triphenylmethyl-L-cysteine (566.4 mg, yield: 77.90%).
References
[1] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0199; 0200; 0201; 0202
S-Trityl-D-cysteine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Aloespharm Co., Ltd. | 021-20960837 | market@aloespharm.com | China | 1299 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sichuan Ampebiochem Co., Ltd. | 028-65294243 18682730901 | sales@ampebiochem.com | China | 1000 | 58 |
