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Ethyl 2-chloropropionate

CAS No.
535-13-7
Chemical Name:
Ethyl 2-chloropropionate
Synonyms
Ethyl 2-chloropropanoate;NSC-522671;oropropionate;2-Chloropropio;UNII:LXW30UR82C;Ethyl 2-chloropropio;3-Nitrosalicyclic Acid;ethyl2-chloropropanoate;Flurbiprofen Impurity 11;ETHYL 2-CHLOROPROPIONATE
CBNumber:
CB9130182
Molecular Formula:
C5H9ClO2
Molecular Weight:
136.58
MDL Number:
MFCD00000864
MOL File:
535-13-7.mol
MSDS File:
SDS
Last updated:2026-05-28 04:35:13

Ethyl 2-chloropropionate Properties

Boiling point 146-149 °C (lit.)
Density 1.072 g/mL at 25 °C (lit.)
refractive index n20/D 1.417(lit.)
Flash point 101 °F
storage temp. Flammables area
solubility alcohol: miscible
form clear liquid
Specific Gravity 1.085 (20/4℃)
color Colorless to Light yellow
Water Solubility immiscible
Merck 14,3785
BRN 773906
Dielectric constant 10.1
InChI 1S/C5H9ClO2/c1-3-8-5(7)4(2)6/h4H,3H2,1-2H3
InChIKey JEAVBVKAYUCPAQ-UHFFFAOYSA-N
SMILES CCOC(=O)C(C)Cl
LogP 1.382 (est)
CAS DataBase Reference 535-13-7(CAS DataBase Reference)
FDA UNII LXW30UR82C
NIST Chemistry Reference Ethyl 2-chloropropionate(535-13-7)
EPA Substance Registry System Ethyl-2-chloropropionate (535-13-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H315-H319-H226
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  10-36/37/38
Safety Statements  26-36-37/39-16
RIDADR  UN 2935
WGK Germany  3
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29159000
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
REACH Registrations Inactive
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
1 0

Ethyl 2-chloropropionate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 192414 Ethyl 2-chloropropionate 97% 535-13-7 25ml $70.9 2026-04-30 Buy
Sigma-Aldrich 192414 Ethyl 2-chloropropionate 97% 535-13-7 1l $609 2026-04-30 Buy
TCI Chemical C0790 Ethyl 2-Chloropropionate >97.0%(GC) 535-13-7 25mL $65 2026-04-30 Buy
TCI Chemical C0790 Ethyl 2-Chloropropionate >97.0%(GC) 535-13-7 100mL $169 2026-04-30 Buy
TRC TRC-E903620-5G Ethyl 2-Chloropropionate 535-13-7 5g $84 2026-06-03 Buy
Product number Packaging Price Buy
192414 25ml $70.9 Buy
192414 1l $609 Buy
C0790 25mL $65 Buy
C0790 100mL $169 Buy
TRC-E903620-5G 5g $84 Buy

Ethyl 2-chloropropionate Chemical Properties, Uses, Production

Description

Ethyl-2-chloropropionate is a liquid with apleasant odor. Molecular weight = 136.8; Boilingpoint = 147℃; Flash point = 41.8℃

Chemical Properties

clear colorless liquid

Chemical Properties

Ethyl-2-chloropropionate is a liquid with a pleasant odor

Uses

Ethyl 2-chloropropionate was used as initiator during the synthesis of poly(2-(diethylamino)ethyl methacrylate) and poly(N-isopropylacrylamide) via atom transfer radical polymerization. It was also used in the synthesis of end-functionalized poly(N-isopropylacrylamide) with pyrenyl group.

General Description

A clear colorless liquid with a pungent odor. Flash point of 100°F. Denser than water and insoluble in water. Vapors are heavier than air.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Ethyl 2-chloropropionate is a halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Potential Exposure

This material is used in organic synthesis.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24- 48 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.

storage

Color Code—Red: Flammability Hazard: Store in aflammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trained onits proper handling and storage. Store in tightly closed containers in a cool, well-ventilated area away from acids, bases,oxidizing and reducing agents. Sources of ignition, such assmoking and open flames, are prohibited where ethyl-2-chloropropionate is used, handled, or stored in a manner thatcould create a potential fire or explosion hazard

Shipping

UN2935 Ethyl 2-chloropropionate, Hazard Class: 3; Labels: 3-Flammable liquid.

Incompatibilities

Flammable liquid; forms explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and reducing agents. Esters are generally incompatible with nitrates. Moisture may cause hydrolysis or other forms of decomposition. Esters react with acids releasing heat in addition to alcohols and acids. Contact with caustic solutions generate heat. Contact with esters with alkali metals and hydrides releases flammable hydrogen.

Global Suppliers ( 267)
Supplier Tel Email Country ProdList Advantage
Zibo Chuanggu Chemical Technology Co., Ltd. 00-15864498288 15864498288 15864498288@163.cn China 53 58
Changzhou Liren Medical Technology Co. Ltd. 0519-85859058 13915836899 2078957504@qq.com China 454 58
Hubei Zhonglong Kangsheng Fine Chemical Co., Ltd. 18171205315; 18171205315 1213219329@qq.com China 988 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57

View Latest Price from Ethyl 2-chloropropionate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 2-chloropropionate pictures 2026-09-02 Ethyl 2-chloropropionate
535-13-7
20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
Ethyl 2-Chloropropionate pictures 2026-05-28 Ethyl 2-Chloropropionate
535-13-7
$10.70 10kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Ethyl 2-chloropropionate pictures 2026-03-20 Ethyl 2-chloropropionate
535-13-7
$10.00 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
2-CHLOROPROPIONIC ACID ETHYL ESTER ETHYL 2-CHLOROPROPIONATE ETHYL ALPHA-CHLOROPROPIONATE 2-chloropropanoicacid,ethylester 2-chloro-propanoicaciethylester ethyl2-chloropropanoate Propanoic acid, 2-chloro-, ethyl ester Propanoicacid,2-chloro-,ethylester 2-Chloropropio Flurbiprofen Impurity 11 oropropionate Propionic acid, 2-chloro-, ethyl ester propionicacid,2-chloro-,ethylester 3-Nitrosalicyclic Acid ethyl-2-chloropropionic acid ETHYL 2-CHLOROPROPIONATE pract Ethyl 2-Chloropropionate 2- 2-Chloropropionic acid ethyl NSC-522671 Ethyl 2-chloropropionate,97% Ethyl a-Chloropropionate Ethyl 2-chloropropio Ethyl 2-chloropropionate, 97% 25ML (+)-2-Chlor-propionsaeure-aethylester 2- chloroethyl propionate Ethyl 2-chloropropionate 97% Ethyl 2-Chloropropionate > UNII:LXW30UR82C (+/-) ethyl 2-Chloropropionate Ethyl 2-Chloropropionate practical grade, 95% Flurbiprofen 1,3-Butylene Glycol Esters (Mixture of Regio- and Stereoisomers) Ethyl (S)-2-chloropropanoate Ethyl 2-Chloropropionate, ≥ 97.0% C11502800 2-ChloropropioniCacid-ethyLester Ethyl 2-chloropropionate 100 μg/ml Acetonitrile ethyl 2-chloropropionate, 98%min Ethyl 2-chloropropanoate 535-13-7 553-13-7 535-13-4 C5H9O2Cl C5H9ClO2 HALOGEN Building Blocks C2 to C5 Carbonyl Compounds Esters Organic Building Blocks API Intermediate C2 to C5 Carbonyl Compounds Esters