KT D606

CAS No.
1429063-06-8
Chemical Name:
KT D606
Synonyms
KT D606;9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 3,3′-(1,7-heptanediyl)bis[2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, (9S,9′S,10R,10′R,12R,12′R)-
CBNumber:
CB914907488
Molecular Formula:
C59H50N6O10
Molecular Weight:
1003.06
MDL Number:
MOL File:
1429063-06-8.mol
Last updated:2025-04-18 09:53:02

KT D606 Properties

Density 1.71±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 3.03±0.60(predicted)

KT D606 Chemical Properties, Uses, Production

Uses

KT D606 is an inhibitor of the PAK kinase family, with an IC50 value of 4 μM. KT D606 selectively blocks the proliferation of cancer cells transformed by oncogenic RAS mutants and can be used for research on RAS/PAK1-induced cancers[1].

References

[1] Nheu TV, et al. The K252a derivatives, inhibitors for the PAK/MLK kinase family selectively block the growth of RAS transformants. Cancer J. 2002 Jul-Aug;8(4):328-36. DOI:10.1097/00130404-200207000-00009

KT D606 Preparation Products And Raw materials

Raw materials

Preparation Products

KT D606 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
KT D606 9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 3,3′-(1,7-heptanediyl)bis[2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, (9S,9′S,10R,10′R,12R,12′R)- 1429063-06-8