Methyl 3-isoquinolinecarboxylate
- CAS No.
- 27104-73-0
- Chemical Name:
- Methyl 3-isoquinolinecarboxylate
- Synonyms
- METHYL ISOQUINOLINE-3-CARBOXYLATE;3-(Methoxycarbonyl)isoquinoline;METHYL 3-ISOQUINOLINECARBOXYLATE;Methyl 3-isoquinolinecarboxylate,98%;Methylisoquinoline-3-carboxylate,98%;3-Isoquinolinecarboxylicacidmethylester;ISOQUINOLINE-3-CARBOXYLIC ACID METHYL ESTER;3-Isoquinolinecarboxylic acid, methyl ester ,98%;Methyl 3-isoquinolinecarboxylate ISO 9001：2015 REACH
- CBNumber:
- CB9188097
- Molecular Formula:
- C11H9NO2
- Molecular Weight:
- 187.19
- MDL Number:
- MFCD00075138
- MOL File:
- 27104-73-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 3-isoquinolinecarboxylate 98% | 338559 | 1g | $83.6 |
| METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 64350 | 1G | $31 |
| METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 64350 | 5G | $47 |
| METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 64350 | 25G | $217 |
| Methyl isoquinoline-3-carboxylate 98% | M55365 | 250mg | $19 |
| More product size | |||
| Melting point | 86-88 °C (lit.) |
|---|---|
| Boiling point | 321.94°C (rough estimate) |
| Density | 1.1963 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder |
| pka | 2.58±0.30(Predicted) |
| Appearance | Off-white to light yellow Solid |
| BRN | 473630 |
| InChI | InChI=1S/C11H9NO2/c1-14-11(13)10-6-8-4-2-3-5-9(8)7-12-10/h2-7H,1H3 |
| InChIKey | ZBCGBIZQNMVMPC-UHFFFAOYSA-N |
| SMILES | C1C2=C(C=CC=C2)C=C(C(OC)=O)N=1 |
| CAS DataBase Reference | 27104-73-0(CAS DataBase Reference) |
| FDA UNII | EQT2546QNR |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Methyl 3-isoquinolinecarboxylate price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 338559 | Methyl 3-isoquinolinecarboxylate 98% | 27104-73-0 | 1g | $83.6 | 2026-04-30 | Buy |
| AstaTech | 64350 | METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 27104-73-0 | 1G | $31 | 2026-04-30 | Buy |
| AstaTech | 64350 | METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 27104-73-0 | 5G | $47 | 2026-04-30 | Buy |
| AstaTech | 64350 | METHYL ISOQUINOLINE-3-CARBOXYLATE 97% | 27104-73-0 | 25G | $217 | 2026-04-30 | Buy |
| Synthonix | M55365 | Methyl isoquinoline-3-carboxylate 98% | 27104-73-0 | 250mg | $19 | 2026-05-06 | Buy |
Methyl 3-isoquinolinecarboxylate Chemical Properties,Uses,Production
Chemical Properties
Cream powder
Uses
Methyl 3-isoquinolinecarboxylate was used in the preparation of 3-acetylisoquinoline.
Definition
ChEBI: Methyl isoquinoline-3-carboxylate is a member of isoquinolines.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 25, p. 1081, 1982 DOI: 10.1021/jm00351a015
Synthesis
79815-19-3
27104-73-0
General procedure for the synthesis of methyl isoquinoline-3-carboxylate from methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate: In a 250 mL aubergine vial, (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (2) (4.23 g, 22.15 mmol) and N,N-dimethylformamide (50 mL) were added. Subsequently, potassium permanganate (2.97 g, 18.79 mmol) was added to the solution. After the reaction was carried out for 6 hours, ethanol (50 mL) was added and stirred for 30 minutes. After that, the solvent was removed and the residue was dissolved with methanol (30 mL). Finally, the residue was purified by column chromatography to give a colorless solid product (858 mg, 24.56% yield).
References
[1] RSC Advances, 2017, vol. 7, # 77, p. 48848 - 48852
[2] Journal of Agricultural and Food Chemistry, 2018, vol. 66, # 34, p. 8957 - 8965
[3] Patent: CN106986825, 2017, A. Location in patent: Paragraph 0023; 0031; 0032
Methyl 3-isoquinolinecarboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18903 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49967 | 58 |
View Lastest Price from Methyl 3-isoquinolinecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | Methyl 3-isoquinolinecarboxylate
27104-73-0
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-12-20 | Methyl 3-isoquinolinecarboxylate
27104-73-0
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- Methyl 3-isoquinolinecarboxylate
27104-73-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Methyl 3-isoquinolinecarboxylate
27104-73-0
- $1.00
- 99%
- Career Henan Chemical Co
