FMOC-PRO-OL
- CAS No.
- 148625-77-8
- Chemical Name:
- FMOC-PRO-OL
- Synonyms
- FMOC-PRO-OL;FMOC-PROLINOL;FMOC-L-PRO-OL;FMOC-L-PROLINOL;N-FMOC-L-PROLINOL;FMOC-PRO-OL USP/EP/BP;N-ALPHA-FMOC-L-PROLINOL;Fmoc-L-prolinol≥ 99% (Assay);(S)-Boc-2-pyrrolidinemethanol;(S)-N-FMOC-2-PYRROLIDINEMETHANOL
- CBNumber:
- CB9200940
- Molecular Formula:
- C20H21NO3
- Molecular Weight:
- 323.39
- MDL Number:
- MFCD00235942
- MOL File:
- 148625-77-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Fmoc-L-prolinol ≥99%(Assay) | 03218 | 1G | $36.65 |
| Fmoc-L-prolinol ≥99%(Assay) | 03218 | 5G | $142.11 |
| (S)-Fmoc-2-(hydroxymethyl)pyrrolidine | FAL1002 | 5g | $300 |
| Fmoc-L-prolinol ≥99%(Assay) | 03218 | 25G | $530.9 |
| (S)-Fmoc-2-(hydroxymethyl)pyrrolidine | FAL1002 | 25g | $1032 |
| More product size | |||
| Melting point | 90℃ |
|---|---|
| Boiling point | 504.6±23.0 °C(Predicted) |
| Density | 1.242±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 14.77±0.10(Predicted) |
| Appearance | White to off-white Solid |
| optical activity | -31.62° (C=0.010056 g/ml, CHCL3, 20°C, 589nm) |
| BRN | 8789847 |
| CAS DataBase Reference | 148625-77-8(CAS DataBase Reference) |
FMOC-PRO-OL price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Chem-Impex | 03218 | Fmoc-L-prolinol ≥99%(Assay) | 148625-77-8 | 1G | $36.65 | 2026-05-19 | Buy |
| Chem-Impex | 03218 | Fmoc-L-prolinol ≥99%(Assay) | 148625-77-8 | 5G | $142.11 | 2026-05-19 | Buy |
| Iris Biotech GmbH | FAL1002 | (S)-Fmoc-2-(hydroxymethyl)pyrrolidine | 148625-77-8 | 5g | $300 | 2026-05-19 | Buy |
| Chem-Impex | 03218 | Fmoc-L-prolinol ≥99%(Assay) | 148625-77-8 | 25G | $530.9 | 2026-05-19 | Buy |
| Iris Biotech GmbH | FAL1002 | (S)-Fmoc-2-(hydroxymethyl)pyrrolidine | 148625-77-8 | 25g | $1032 | 2026-05-19 | Buy |
FMOC-PRO-OL Chemical Properties,Uses,Production
Chemical Properties
White or off-white Powder
Uses
Fmoc-l-prolinol is a useful intermediate for organic synthesis.
Synthesis
82911-69-1
23356-96-9
148625-77-8
(1) Synthesis of Fmoc-L-prolinol (Compound 2): L-prolinol (Compound 1) (0.61 g, 6.0 mmol) was dissolved in 70 mL of deionized water to prepare an aqueous solution of L-prolinol. N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-OSu) (2.0 g, 6.0 mmol) was dissolved in 10 mL of tetrahydrofuran (THF). This THF solution was slowly added to the aqueous L-prolinol solution and the reaction was stirred for 1 hour at room temperature. After completion of the reaction, the reaction mixture was separated into liquid and solid phases. These two portions were extracted with ethyl acetate, respectively, and the organic layers were combined. The combined organic layers were dried by adding anhydrous sodium sulfate to the combined organic layers. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate=1:1, v/v) to afford compound 2 (1.4 g, 74% yield). The nuclear magnetic resonance hydrogen spectrum (1H-NMR) data of the compound were as follows: 1H-NMR (CDCl3): δ 7.77 (2H, d, J = 7.7 Hz, Ar-H), 7.60 (2H, d, J = 7.3 Hz, Ar-H), 7.40 (2H, t, J = 7.5 Hz, Ar-H), 7.31 (2H, t, J = 7.6 Hz Ar-H), 4.40-4.50 (2H, m, COOCH2), 4.22 (1H, t, J = 6.5 Hz, Ar-CH), 3.20-3.80 (5H, m, H-5, H-6), 1.75 (3H, m, H-3, H-4), 1.40 (1H, m, H-3).
References
[1] Patent: US9200278, 2015, B2. Location in patent: Page/Page column 39; 40; 41; 42
FMOC-PRO-OL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1100 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from FMOC-PRO-OL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-29 | Fmoc-L-Pro-ol
148625-77-8
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2020-01-06 | Fmoc-L-Pro-ol
148625-77-8
|
$1.00 | 1g | 98% | 100KG | Sichuan Jiaying Lai Technology Co.,LTD |
-
- Fmoc-L-Pro-ol
148625-77-8
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- Fmoc-L-Pro-ol
148625-77-8
- $1.00
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
