2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester
- CAS No.
- 655235-65-7
- Chemical Name:
- 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester
- Synonyms
- Methyl 3-chloro-5-(trifluoromethyl)picolinate;methyl 3-chloro-5-trifluoromethyl-2-pyridinecarboxylate;2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl este;3-Chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid methyl ester;2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester;Methyl 3-chloro-5-(trifluoromethyl)picolinate, 3-Chloro-2-(methoxycarbonyl)-5-(trifluoromethyl)pyridine
- CBNumber:
- CB92079623
- Molecular Formula:
- C8H5ClF3NO2
- Molecular Weight:
- 239.58
- MDL Number:
- MFCD01570523
- MOL File:
- 655235-65-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylate ≥95% | PC31856 | 250mg | $21 |
| 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester | 132427 | 5.00g | $1180 |
| 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester | 132427 | 10.00g | $1728 |
| Methyl 3-chloro-5-(trifluoromethyl)picolinate >98% | M61646 | 1g | $30 |
| Methyl 3-chloro-5-(trifluoromethyl)picolinate >98% | M61646 | 5g | $80 |
| More product size | |||
| Boiling point | 260℃ |
|---|---|
| Density | 1.443 |
| Flash point | 111℃ |
| storage temp. | Store at room temperature |
| pka | -3.33±0.10(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C8H5ClF3NO2/c1-15-7(14)6-5(9)2-4(3-13-6)8(10,11)12/h2-3H,1H3 |
| InChIKey | IBDYTWWXSCCQRL-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC=C(C(F)(F)F)C=C1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P280 |
| HS Code | 2933399990 |
2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC31856 | Methyl 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylate ≥95% | 655235-65-7 | 250mg | $21 | 2026-06-04 | Buy |
| Matrix Scientific | 132427 | 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester | 655235-65-7 | 5.00g | $1180 | 2026-05-18 | Buy |
| Matrix Scientific | 132427 | 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester | 655235-65-7 | 10.00g | $1728 | 2026-05-18 | Buy |
| Synthonix | M61646 | Methyl 3-chloro-5-(trifluoromethyl)picolinate >98% | 655235-65-7 | 1g | $30 | 2026-05-06 | Buy |
| Synthonix | M61646 | Methyl 3-chloro-5-(trifluoromethyl)picolinate >98% | 655235-65-7 | 5g | $80 | 2026-05-06 | Buy |
2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester Chemical Properties,Uses,Production
Synthesis
67-56-1
![2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]malononitrile](/StructureFile/ChemBookStructure20/GIF/CB2957463.gif)
338956-33-5
655235-65-7
GENERAL STEPS: Add heteroaromatic malononitrile (1.0 equiv., prepared according to Ref. 6) and the indicated solvent (1 mL / 0.12 mmol) to the reaction vessel. With stirring at room temperature, 4molecular sieves were added. A solution of anhydrous m-CPBA (1.5 eq.) was prepared by dissolving it in the indicated solvent (1 mL / 0.22 mmol) and drying over molecular sieves (4) for 10 min. The solution was added dropwise to the reaction mixture, followed by continued stirring for 10 min. After addition of nucleophilic reagent, the reaction mixture was kept stirring at room temperature. Upon completion of the reaction, the reaction was quenched with aqueous sodium thiosulfate and extracted with dichloromethane (CH2Cl2). The organic phases were combined, washed twice sequentially with saturated aqueous sodium bicarbonate (NaHCO3) and brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. Finally, purification was carried out by preparative high performance liquid chromatography (HPLC).
References
[1] Synlett, 2015, vol. 26, # 10, p. 1365 - 1370
2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23504 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8642 | 58 |
View Lastest Price from 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-06 | 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester
655235-65-7
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester
655235-65-7
- $1.00
- 99%
- Career Henan Chemical Co
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