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5-(Trifluoromethyl)pyridine-2-carboxylic acid

5-(Trifluoromethyl)pyridine-2-carboxylic acid structure

CAS No.: 80194-69-0

Chemical Name:: 5-(Trifluoromethyl)pyridine-2-carboxylic acid

Synonyms: 5-(TRIFLUOROMETHYL)PICOLINIC ACID;5-Trifluoromethyl-2-Pyridineca;5-trifluoro-2-pyridinecarboxylic acid;5-TRIFLUOROMETHYL-2-PYRIDINECARBOXYLIC ACID;2-Carboxylic acid-5-trifluoromethylpyridine;5-(Trifluoromethyl)pyridine-2-carboxylicaci;5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID;5- three-2-forMic acidfluorineMethyl pyridine;5-(Trifluoromethy1)pyridine-2-carboxylic acid;5-((trifluoromethyl))-pyridin-2-carboxylic acid

CBNumber:: CB4476461

Molecular Formula:: C7H4F3NO2

Molecular Weight:: 191.11

MDL Number:: MFCD04113632

MOL File:: 80194-69-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:46:02

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5-(Trifluoromethyl)pyridine-2-carboxylic acid Properties

Melting point	135-137°C
Boiling point	273.7±40.0 °C(Predicted)
Density	1.484±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.13±0.10(Predicted)
form	Powder
color	Pale brown
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C7H4F3NO2/c8-7(9,10)4-1-2-5(6(12)13)11-3-4/h1-3H,(H,12,13)
InChIKey	NJHGVAYLDHROPT-UHFFFAOYSA-N
SMILES	C1(C(O)=O)=NC=C(C(F)(F)F)C=C1
CAS DataBase Reference	80194-69-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

WGK Germany

HazardClass

IRRITANT

HS Code

2933399990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

5-(Trifluoromethyl)pyridine-2-carboxylic acid price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	700630	5-(Trifluoromethyl)pyridine-2-carboxylic acid 95%	80194-69-0	500mg	$137	2026-04-30	Buy
TCI Chemical	T2975	5-(Trifluoromethyl)-2-pyridinecarboxylic Acid >98.0%(GC)(T)	80194-69-0	1g	$31	2026-04-30	Buy
TCI Chemical	T2975	5-(Trifluoromethyl)-2-pyridinecarboxylic Acid >98.0%(GC)(T)	80194-69-0	5g	$113	2026-04-30	Buy
Usbiological	291527	5-(Trifluoromethyl)pyridine-2-carboxylic acid Asreported	80194-69-0	2g	$349	2026-06-03	Buy
Usbiological	291527	5-(Trifluoromethyl)pyridine-2-carboxylic acid Asreported	80194-69-0	5g	$605	2026-06-03	Buy

Product number	Packaging	Price	Buy
700630	500mg	$137	Buy
T2975	1g	$31	Buy
T2975	5g	$113	Buy
291527	2g	$349	Buy
291527	5g	$605	Buy

5-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties, Uses, Production

Uses

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

Uses

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

5-(Trifluoromethyl)pyridine-2-carboxylic acid synthesis

Synthesis of 5-(Trifluoromethyl)pyridine-2-carboxylic acid from Methanol and carbon monoxide and 2-Chloro-5-trifluoromethylpyridine

5-(Trifluoromethyl)pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

(Trifluoromethyl)trimethylsilane Hexane Nitrogen N-Methyl-2-pyrrolidone N,N-Dimethylformamide

Toluene Carbon dioxide Tetrahydrofuran Diethyl ether Iodine

Ethyl acetate 2,5-Dibromopyridine n-Butyllithium 2-Bromo-5-(trifluoromethyl)pyridine 2-Iodo-5-trifluoromethylpyridine

5-(Trifluoromethyl)picolinonitrile

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Preparation Products

5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester

5-(Trifluoromethyl)pyridine-2-carboxylic acid Suppliers

Global Suppliers ( 223)

Supplier	Tel	Email	Country	ProdList	Advantage
Fuxin Custchem Fine Chemical Co., Ltd.	0418-5113999 18740177324	sales@custchem.com.cn	China	448	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.	0311-89250318 13582355795	master@sjzsdyn.com	China	2776	65

Supplier	Advantage
Fuxin Custchem Fine Chemical Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
future industrial shanghai co., ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.	65

View Latest Price from 5-(Trifluoromethyl)pyridine-2-carboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0	$5.00	1KG	98%		Henan Fengda Chemical Co., Ltd
2026-08-20	5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2026-06-30	5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

5-(Trifluoromethyl)pyridine-2-carboxylic acid
80194-69-0
$5.00
98%
Henan Fengda Chemical Co., Ltd

5-(Trifluoromethyl)pyridine-2-carboxylic acid
80194-69-0
$1.10
99.00%
Dideu Industries Group Limited

5-(Trifluoromethyl)pyridine-2-carboxylic acid
80194-69-0
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

5-(Trifluoromethyl)pyridine-2-carboxylic acid Spectrum

5-(Trifluoromethyl)pyridine-2-carboxylic acid(80194-69-0)¹HNMR

80194-69-0 (5-(Trifluoromethyl)pyridine-2-carboxylic acid) Related Search:

4-Methylpyridine 4-(Trifluoromethyl)pyridine 2-Chloro-5-trifluoromethylpyridine 3-（trifluoromethyl) Cinnamaldehyde Pyridine

2-Fluoro-5-trifluoromethylpyridine 2-(Trifluoromethyl)pyridine 2-Picoline 2,6-Lutidine 3-(Trifluoromethyl)benzoic acid

(Trifluoromethyl)trimethylsilane Chromium picolinate 2,3,5-Trifluoropyridine 3-Trifluoromethylpyridine Folic acid

2-Picolinic acid 2,5-Pyridinedicarboxylic acid 3-(Trifluoromethyl)benzaldehyde

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5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID 5-TRIFLUOROMETHYL-2-PYRIDINECARBOXYLIC ACID 5-Trifluoromethyl-2-Pyridineca 5-(Trifluoromethyl)pyridine-2-carboxylic acid 97% 5-(Trifluoromethyl)pyridine-2-carboxylicacid97% 5-trifluoro-2-pyridinecarboxylic acid 5-(Trifluoromethyl)picolinic acid, 2-Carboxy-5-(trifluoromethyl)pyridine 5- three-2-forMic acidfluorineMethyl pyridine 5--2-three fluorineMethyl pyridinecarboxylic acid 5-((trifluoromethyl))-pyridin-2-carboxylic acid 5-(Trifluoromethyl)picolinic acid, 2-Carboxy-5-(trif 2-Pyridinecarboxylic acid, 5-(trifluoromethyl)- 5-(Trifluoromethyl)pyridine-2-carboxylic acid ISO 9001：2015 REACH 5-(Trifluoromethy1)pyridine-2-carboxylic acid 2-Carboxylic acid-5-trifluoromethylpyridine 5-(Trifluoromethyl)pyridine-2-carboxylicaci 5-(TRIFLUOROMETHYL)PICOLINIC ACID 80194-69-0 Carboxylic Acids Pyridines Carboxylic Acids Fluorine series