2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
- CAS No.
- 871839-91-7
- Chemical Name:
- 2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
- Synonyms
- 2-ISOPROXYPYRIDINE-5-BORONIC ACID PINACOLATE;2-Isoproxypyridine-4-boronic acid pinacol ester;2-isopropoxypyridine -5-boronic acid pinacolate;6-Isopropoxy-3-pyridylboronic Acid Pinacol Ester;2-isopropoxy-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-(propan-2-yloxy)-5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-(6-Isopropoxy-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE;2-propan-2-yloxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;Pyridine,2-(1-methylethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber:
- CB9213601
- Molecular Formula:
- C14H22BNO3
- Molecular Weight:
- 263.14
- MDL Number:
- MFCD07368871
- MOL File:
- 871839-91-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | I1099 | 200MG | $31 |
| 2-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | I1099 | 1G | $103 |
| 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | OR360292 | 250mg | $21 |
| 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | OR360292 | 1g | $24 |
| 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | OR360292 | 5g | $82 |
| More product size | |||
| Melting point | 72-75℃ |
|---|---|
| Boiling point | 347.6±27.0 °C(Predicted) |
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 4.23±0.24(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | I1099 | 2-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 871839-91-7 | 200MG | $31 | 2026-04-30 | Buy |
| TCI Chemical | I1099 | 2-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | 871839-91-7 | 1G | $103 | 2026-04-30 | Buy |
| Apolloscientific | OR360292 | 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | 871839-91-7 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR360292 | 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | 871839-91-7 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR360292 | 2-Isopropoxypyridine-5-boronic acid, pinacol ester >97% | 871839-91-7 | 5g | $82 | 2026-06-04 | Buy |
2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Chemical Properties,Uses,Production
Uses
2-Isopropoxypyridine-5-boronic acid, pinacol ester
Synthesis
870521-31-6
73183-34-3
871839-91-7
Under nitrogen protection, to a stirred 1,4-dioxane (50 ml) of 5-bromo-2-isopropoxypyridine (5 g, 23.14 mmol), potassium acetate (5.68 g, 57.9 mmol), and 4,4,4,4,5,5,5,5-octamethyl-2,2'-bis(1,3,2-dioxaborolane) (8.81 g, 34.7 mmol) PdCl2(dppf)-DCM adduct (1.89 g, 2.314 mmol) was added to the suspension. The reaction mixture was heated at 110°C for 1 hour. After completion of the reaction, water was added to the mixture and extracted with ethyl acetate. The organic layers were combined, washed sequentially with water and brine, dried with Na2SO4 and concentrated under reduced pressure. The crude product was purified by column chromatography to afford 6-isopropoxypyridine-3-boronic acid pinacol ester as an oil (5 g, 82% yield).1H NMR (400 MHz, chloroform-d) δ 8.54 (s, 1H), 7.92 (d, J = 8.3Hz, 1H), 6.76-6.46 (m, 1H), 5.45-5.25 (m, 1H), and 1.37 (d, J = 2.4Hz, 6H), 1.28 (s, 12H).
References
[1] Patent: WO2017/37682, 2017, A1. Location in patent: Page/Page column 71; 72
[2] Patent: WO2005/123675, 2005, A1. Location in patent: Page/Page column 55
[3] Patent: WO2016/161160, 2016, A1. Location in patent: Paragraph 0160
[4] ACS Medicinal Chemistry Letters, 2018, vol. 9, # 7, p. 761 - 767
[5] Patent: WO2009/105500, 2009, A1. Location in patent: Page/Page column 219-220
2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14036 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5898 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| Xi'an Yutbon Pharmaceutical Technology Co., Ltd | 029-81140587 | sales@yutbon.com | China | 452 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
View Lastest Price from 2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
871839-91-7
|
$1.00 | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- 2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
871839-91-7
- $1.00
- 98%
- Career Henan Chemical Co
871839-91-7(2-ISOPROPOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE)Related Search:
1of3
