Carzenide
- CAS No.
- 138-41-0
- Chemical Name:
- Carzenide
- Synonyms
- 4-SULFAMOYLBENZOIC ACID;Dirnate;4-SULFAMYLBENZOIC ACID;P-SULFAMOYLBENZOIC ACID;4-CARBOXYBENZENESULPHONAMIDE;NSC2675;Carzenid;NSC 2675;NSC-2675;CARZENIDE
- CBNumber:
- CB9220906
- Molecular Formula:
- C7H7NO4S
- Molecular Weight:
- 201.2
- MDL Number:
- MFCD00007938
- MOL File:
- 138-41-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 285-295 °C (lit.) |
|---|---|
| Boiling point | 449.0±47.0 °C(Predicted) |
| Density | 1.5083 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.5g/l |
| form | Powder |
| pka | 3.50(at 25℃) |
| color | White |
| Water Solubility | 453 mg/L (25 ºC) |
| Merck | 14,1876 |
| BRN | 1875393 |
| InChI | 1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) |
| InChIKey | UCAGLBKTLXCODC-UHFFFAOYSA-N |
| SMILES | O=S(C(C=C1)=CC=C1C(O)=O)(N)=O |
| CAS DataBase Reference | 138-41-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 30Z5HQB5A4 |
| NIST Chemistry Reference | P-sulfamoylbenzoic acid(138-41-0) |
| EPA Substance Registry System | 4-Aminosulfonylbenzoic acid (138-41-0) |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DH6820000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | LD50 i.p. in rats: 350 ± 22 mg/kg (Appenroth, Brunlich) | |||||||||
| NFPA 704 |
|
Carzenide price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C11804 | 4-Sulfamoylbenzoic acid 97% | 138-41-0 | 5g | $40.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | C11804 | 4-Sulfamoylbenzoic acid 97% | 138-41-0 | 100g | $229 | 2026-04-30 | Buy |
| TCI Chemical | S0323 | 4-Sulfamoylbenzoic Acid >95.0%(T) | 138-41-0 | 25g | $25 | 2026-04-30 | Buy |
| TCI Chemical | S0323 | 4-Sulfamoylbenzoic Acid >95.0%(T) | 138-41-0 | 500g | $250 | 2026-04-30 | Buy |
| Usbiological | 289488 | 4-Sulfamylbenzoic acid Asreported | 138-41-0 | 250g | $372 | 2026-06-03 | Buy |
Carzenide Chemical Properties,Uses,Production
Description
4-Sulfamoylbenzoic acid is a significant class of compounds extensively investigated for their potential applications across various disciplines. Characterized by a nitrogen-containing ring structure, 4-Sulfamoylbenzoic acid is a heterocyclic compound adorned with diverse substituents encircling the ring. Within the body, 4-Sulfamoylbenzoic acid is an agonist for several receptors, including those for serotonin and dopamine. By forming connections with these receptors, 4-Sulfamoylbenzoic acid proficiently modulates their functionality, consequently inducing changes in receptor behavior. This, in turn, precipitates an array of effects contingent upon the specific receptor and the studied drug.
Chemical Properties
White powder
Uses
diuretic, carbonic anhydrase inhibitor
Uses
4-Sulfamoylbenzoic Acid (Carzenide) is used as a reagent in the synthesis of carbonic anhydrase inhibitors anticonvulsant agents.
Definition
ChEBI: Carzenide is a sulfonamide.
Application
Carzenide is an antispasmodic that has been used in the treatment of dysmenorrhoea. Currently Carzenide is an organic synthesis intermediate, used for synthetic drug.
reaction suitability
reagent type: cross-linking reagent
Synthesis
70-55-3
138-41-0
Example 11: In a 25 mL reaction vial, 1 mmol of p-carboxybenzenesulfonamide, 0.05 mmol of 3,5-dinitro-N-hydroxy-N-methylbenzamide, and 0.01 mmol of cobalt acetate were added, followed by the addition of 5 mL of acetic acid as solvent. The reaction system was placed in an oxygen atmosphere, maintaining an oxygen pressure of 1 atmosphere, and the temperature was raised to 100 °C. The reaction lasted for 10 hours. After completion of the reaction, the reaction mixture was cooled to room temperature. Recovery of acetic acid was achieved by removing acetic acid from the filtrate by distillation under reduced pressure. The residue was washed repeatedly with water to remove residual acetic acid and cobalt acetate co-catalyst, and then washed with a small amount of acetone to remove 3,5-dinitro-N-hydroxy-N-methylbenzamide and a small amount of p-hydroxymethylbenzenesulfonimide. The resulting filter cake was dried to give p-carboxybenzenesulfonamide. The yield of the reaction was 94.05%, the conversion of p-toluenesulfonamide was 99.33% and the selectivity of p-carboxybenzenesulfonamide was 94.68%. The product was analyzed by Agilent 1200 HPLC and the purity was 95.14%.
References
[1] Patent: CN105801455, 2016, A. Location in patent: Paragraph 0048
[2] Patent: US2004/58977, 2004, A1. Location in patent: Page/Page column 8; 14
[3] American Chemical Journal, 1885, vol. 7, p. 147
[4] Justus Liebigs Annalen der Chemie, 1875, vol. 178, p. 284
[5] Journal of the Chemical Society, 1951, p. 1877,1880
Carzenide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Red Sun Pharmaceutical Co., Ltd. | 0519-85223897 13766960291;18651984085;18502596050 | zjc@czredsunpharm.com | China | 46 | 58 |
| Puyang Anruida New Materials Research and Development Co., Ltd. | 18367380348 13305832579 | sales@jxartech.com | China | 61 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Lastest Price from Carzenide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | Carzenide
138-41-0
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-28 | Carzenide
138-41-0
|
$10.00 | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-04-22 | Carzenide
138-41-0
|
$29.00 | 98.65% | 10g | TargetMol Chemicals Inc. |
