ChemicalBook >> CAS DataBase List >>2-Methylcinnamic acid

2-Methylcinnamic acid

2-Methylcinnamic acid structure

CAS No.: 2373-76-4

Chemical Name:: 2-Methylcinnamic acid

Synonyms: o-Methylcinnamic acid;(E)-3-(o-Tolyl)acrylic acid;5-Bromovaniline;2-Methylciamic acid;RARECHEM BK HC T303;TIMTEC-BB SBB003946;2-Methylcinnamicaci;2-METHYLCINNAMIC ACID;SPECS AI-942/25034752;METHYLCINNAMIC ACID,2-

CBNumber:: CB9297335

Molecular Formula:: C10H10O2

Molecular Weight:: 162.19

MDL Number:: MFCD00016841

MOL File:: 2373-76-4.mol

MSDS File:: SDS

Last updated:2026-05-28 06:26:22

Product description	Number	Pack Size	Price
2-Methylcinnamic acid, predominantly trans 99%	433101	5g	$63.1
2-Methylcinnamic Acid >98.0%(GC)(T)	M1295	5g	$36
2-Methylcinnamic Acid >98.0%(GC)(T)	M1295	25g	$117
2-Methylcinnamic acid, predominantly trans	FM34156	0.1kg	$150
2-Methylcinnamic acid, predominantly trans	FM34156	0.25kg	$292.19
More product size

Request For Quotation

2-Methylcinnamic acid Properties

Melting point	174-176 °C(lit.)
Boiling point	228.88°C (rough estimate)
Density	1.0281 (rough estimate)
refractive index	1.5766 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	almost transparency in Methanol
form	powder to crystal
pka	4.5(at 25℃)
color	White to Almost white
BRN	2500607
InChI	1S/C10H10O2/c1-8-4-2-3-5-9(8)6-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-6+
InChIKey	RSWBWHPZXKLUEX-VOTSOKGWSA-N
SMILES	Cc1ccccc1\C=C\C(O)=O
LogP	2.870 (est)
CAS DataBase Reference	2373-76-4(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Risk Statements

36/37/38

Safety Statements

37/39-26-36-24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29163990

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

2-Methylcinnamic acid price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	433101	2-Methylcinnamic acid, predominantly trans 99%	2373-76-4	5g	$63.1	2026-04-30	Buy
TCI Chemical	M1295	2-Methylcinnamic Acid >98.0%(GC)(T)	2373-76-4	5g	$36	2026-04-30	Buy
TCI Chemical	M1295	2-Methylcinnamic Acid >98.0%(GC)(T)	2373-76-4	25g	$117	2026-04-30	Buy
Biosynth	FM34156	2-Methylcinnamic acid, predominantly trans	2373-76-4	0.1kg	$150	2026-06-04	Buy
Biosynth	FM34156	2-Methylcinnamic acid, predominantly trans	2373-76-4	0.25kg	$292.19	2026-06-04	Buy

Product number	Packaging	Price	Buy
433101	5g	$63.1	Buy
M1295	5g	$36	Buy
M1295	25g	$117	Buy
FM34156	0.1kg	$150	Buy
FM34156	0.25kg	$292.19	Buy

2-Methylcinnamic acid Chemical Properties,Uses,Production

Chemical Properties

White flakes or crystal

Uses

2-Methylcinnamic acid may be used as starting reagent for the total synthesis of the cytotoxic alkaloid, 22-hydroxyacuminatine and for the preparation of (E)-2-methylcinnamic acid i-butylammonium salt.

Definition

ChEBI: 2-Methylcinnamic Acid is a member of cinnamic acids.

General Description

2-Methylcinnamic acid has been reported to exhibit strong anti-fungal activity against white-rot fungus Lenzites betulina and brown-rot fungus Laetiporus sulphureus. Hydrogenation of 2-methylcinnamic acid using Walphos ligands and their biferrocene analogs has been studied.

Synthesis

141-82-2

529-20-4

939-57-1

GENERAL STEPS: 2-Methylbenzaldehyde (50 g, 417 mmol) was dissolved in pyridine (2 eq., 65 mL) under stirring conditions, followed by the addition of malonic acid (86.6 g, 834 mmol). The reaction mixture was heated to reflux for 4-5 hours. Upon completion of the reaction, the mixture was slowly poured into ice water and then acidified with 1N HCl. The precipitated white solid was collected by filtration, washed with water and dried under high vacuum for 3-4 h to give (E)-3-(o-tolyl)acrylic acid (57 g, 87% yield).

References

[1] Patent: US2013/178457, 2013, A1. Location in patent: Paragraph 0173
[2] Patent: WO2013/5168, 2013, A2. Location in patent: Page/Page column 32
[3] Tetrahedron Letters, 2011, vol. 52, # 41, p. 5371 - 5374
[4] Journal of Organic Chemistry, 1986, vol. 51, # 7, p. 1120 - 1123
[5] Patent: WO2013/74892, 2013, A1. Location in patent: Page/Page column 39-40

2-Methylcinnamic acid Preparation Products And Raw materials

Raw materials

Malonic acid 2-Methylbenzaldehyde

Preparation Products

(S)-3-AMINO-3-(2-METHYL-PHENYL)-PROPIONIC ACID (2E)-3-(2-Methylphenyl)acryloyl chloride 2-Propen-1-one, 3-(2-methylphenyl)-1-(1-piperazinyl)-

2-Methylcinnamic acid Suppliers

Global( 211)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325	sales1@chuanghaibio.com	China	5218	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20120	58
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21193	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29792	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34563	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-17392587031	1059@dideu.com	China	9996	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52704	58
Zhuoer Chemical Co., Ltd	02120970332;	sales@zhuoerchem.com	China	2904	58
CD Chemical Group Limited	+86-13651442114	info@codchem.com	China	17259	58
Labnetwork lnc.	+86-27-50766799 +86-18062016861	contact@labnetwork.com	China	19987	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Accela ChemBio Inc.	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhuoer Chemical Co., Ltd	58
CD Chemical Group Limited	58
Labnetwork lnc.	58

View Lastest Price from 2-Methylcinnamic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-09	2-Methylcinnamic acid 2373-76-4	$1.10-34.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2026-05-28	2-Methylcinnamic Acid 2373-76-4	$10.00	1KG	99.8%	100tons	Hebei Chuanghai Biotechnology Co,.LTD
2020-01-13	2-Methylcinnamic acid 2373-76-4	$1.00	1KG	98%-99.9%	100kg	Career Henan Chemical Co

2-Methylcinnamic acid
2373-76-4
$1.10-34.00
99%
Henan Fengda Chemical Co., Ltd

2-Methylcinnamic Acid
2373-76-4
$10.00
99.8%
Hebei Chuanghai Biotechnology Co,.LTD

2-Methylcinnamic acid
2373-76-4
$1.00
98%-99.9%
Career Henan Chemical Co

2-Methylcinnamic acid Spectrum

2-Methylcinnamic acid(2373-76-4)MS 2-Methylcinnamic acid(2373-76-4)¹HNMR 2-Methylcinnamic acid(2373-76-4)¹³CNMR 2-Methylcinnamic acid(2373-76-4)IR1 2-Methylcinnamic acid(2373-76-4)IR2

2373-76-4(2-Methylcinnamic acid)Related Search:

POLYMETHACRYLATE Ethyl methacrylate Stearyl Methacrylate 4-Nitrocinnamic acid 3-Nitrocinnamic acid

Methyl methacrylate 2-Hydroxyethyl methacrylate Methacrylic acid Butyl methacrylate trans-Cinnamic acid

Octyl 4-methoxycinnamate 4-Bromocinnamic acid Ethyl cinnamate Methyl cinnamate Citric acid

Ascoric Acid à-methylcinnamic acid,ALPHA-METHYLCINNAMIC ACID,A-METHYLCINNAMIC ACID 9-FLUORENYLIDENEACETIC ACID

1of4

2-METHYLCINNAMIC ACID 3-O-TOLYL-ACRYLIC ACID METHYLCINNAMIC ACID,2- 2-methylcinnamic acid, predominantly trans trans-2-Methylcinnamic acid 2-METHYLCINNAMIC ACID, 99%, PREDOMINANTL Y TRANS 5-Bromovaniline 2-Methylcinnamicacid,98+% 2-Methylbenzeneacrylic acid 2-Methylcinnamic acid,99% 2-Methylciamic acid (E)-3-(o-tolyl)prop-2-enoic acid trans-3-Methylcinnamic acid 2-MethylcinnaMic acid, 99% 10GR 2-MethylcinnaMic Acid, PredoMinantly trans, 97+% RARECHEM BK HC T303 SPECS AI-942/25034752 TIMTEC-BB SBB003946 3-(2-METHYLPHENYL)-2-PROPENOIC ACID 2-Methylcinnamic acid, predominantly trans 99% (E)-3-(2-Methylphenyl)-2-propenoic acid (E)-3-(2-methylphenyl)acrylic acid 3-(2-methylphenyl)prop-2-enoic acid 2-MethylcinnamicAcid> 2-Propenoic acid, 3-(2-methylphenyl)- 2-Methylcinnamicaci 2-Methylcinnamic acid USP/EP/BP METHYLCINNAMIC ACID,2,2-Methylciamic acid,3-(o-Tolyl)acrylic acid,o-Methylcinnamic acid,RARECHEM BK HC T303,3-O-TOLYL-ACRYLIC ACID,5- ortho-methyl cinnamic acid 2-Methylcinnamic acid, predominantly trans (E)-3-(o-Tolyl)acrylic acid o-Methylcinnamic acid 2373-76-4 2373-79-4 CH3C6H4CHCHCOOH Carboxylic Acids Carbonyl Compounds C10 Building Blocks Organic Building Blocks Aromatic Cinnamic Acids, Esters and Derivatives Cinnamic acid C10 Carbonyl Compounds Carboxylic Acids Building Blocks Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks 2373-76-4 11