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2-Mercapto-5-methoxybenzimidazole

2-Mercapto-5-methoxybenzimidazole Structure
2-Mercapto-5-methoxybenzimidazole structure
CAS No.
37052-78-1
Chemical Name:
2-Mercapto-5-methoxybenzimidazole
Synonyms
5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;Esomeprazole impurity A;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-Methoxye-2-mercaplobenzinidazole;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy
CBNumber:
CB9313620
Molecular Formula:
C8H8N2OS
Molecular Weight:
180.23
MDL Number:
MFCD00134581
MOL File:
37052-78-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:56:22
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2-Mercapto-5-methoxybenzimidazole Properties

Melting point 261-263 °C(lit.)
Boiling point 309.4±44.0 °C(Predicted)
Density 1.2425 (rough estimate)
vapor pressure 0.001Pa at 25℃
refractive index 1.5690 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Sparingly)
form Powder
pka 10.13±0.30(Predicted)
color Off-white to light yellow-brown
Water Solubility insoluble
Sensitive Air Sensitive
BRN 3605123
InChI 1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)
InChIKey KOFBRZWVWJCLGM-UHFFFAOYSA-N
SMILES COc1ccc2[nH]c(S)nc2c1
LogP 1.52-2.399
CAS DataBase Reference 37052-78-1(CAS DataBase Reference)
FDA UNII 143562LXX0
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37-22
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29332900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 3
Skin Sens. 1
REACH Registrations Active
NFPA 704
1
2 0

2-Mercapto-5-methoxybenzimidazole price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382485 5-Methoxy-2-benzimidazolethiol 99% 37052-78-1 5g $57.8 2026-04-30 Buy
Sigma-Aldrich 1478480 Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard 37052-78-1 15mg $1290 2026-04-30 Buy
TCI Chemical M1256 2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T) 37052-78-1 25g $65 2026-04-30 Buy
Usbiological 281537 5-Methoxy-2-mercaptobenzimidazole Asreported 37052-78-1 500g $792 2026-06-03 Buy
Usbiological 281537 5-Methoxy-2-mercaptobenzimidazole Asreported 37052-78-1 1kg $1135 2026-06-03 Buy
Product number Packaging Price Buy
382485 5g $57.8 Buy
1478480 15mg $1290 Buy
M1256 25g $65 Buy
281537 500g $792 Buy
281537 1kg $1135 Buy

2-Mercapto-5-methoxybenzimidazole Chemical Properties,Uses,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

2-Mercapto-5-methoxybenzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

Ufiprazole Omeprazole 2-[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(2-nitrophenyl)acetamide

2-Mercapto-5-methoxybenzimidazole Suppliers

Global( 786)Suppliers
Supplier Tel Email Country ProdList Advantage
Hunan Eurasian Pharmaceutical Co. Ltd. 0592-5789919 13328776692 2851802018@qq.com;2851802016@qq.com China 88 58
Suzhou ARTK Medchem Co., Ltd. 18168183658 sales1@artkmedchem.com China 782 58
Xiamen keerda Biotechnology Co., Ltd 0592-5639388; 18060983084 753760940@qq.com China 132 58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd 18317105404 marketing002@witofly.com China 1600 58
Huaian Jiamu Biotechnology Co., Ltd. 0517-83187139 18205232085 cai@jiamu-bio.com China 2999 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Supplier Advantage
Hunan Eurasian Pharmaceutical Co. Ltd. 58
Suzhou ARTK Medchem Co., Ltd. 58
Xiamen keerda Biotechnology Co., Ltd 58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd 58
Huaian Jiamu Biotechnology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
future industrial shanghai co., ltd 65
Alfa Aesar 84

View Lastest Price from 2-Mercapto-5-methoxybenzimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Methoxy-2-mercaptobenzimidazole pictures 2026-09-11 5-Methoxy-2-mercaptobenzimidazole
37052-78-1
 1ASSAYS 99% 50mt Jinan Finer Chemical Co., Ltd
5-methyoxy-2-mercapto Benzimidazole pictures 2026-09-11 5-methyoxy-2-mercapto Benzimidazole
37052-78-1
 1KG 97%-102% 10 tons WUHAN FORTUNA CHEMICAL CO., LTD
5-Methoxy-2-Mercaptobenzimidazole pictures 2026-05-28 5-Methoxy-2-Mercaptobenzimidazole
37052-78-1
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD

2-Mercapto-5-methoxybenzimidazole Spectrum

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)MS2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)1HNMR2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)13CNMR2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR12-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR22-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)Raman

37052-78-1(2-Mercapto-5-methoxybenzimidazole)Related Search:

Thioglycolic acid 2-Mercaptobenzimidazole 2-Methoxyethanol Benzimidazole 2-Methylbenzimidazole
3-Mercaptopropionic acid 2-Ethylhexyl mercaptoacetate OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Ufiprazole Calcium thioglycolate
Omeprazole Esomeprazole Impurity 3 (S)-4-Desmethoxy-4-chloro Omeprazole 4-Hydroxy Omeprazole Omeprazole EP Impurity F
Omeprazole Sulfone N-Oxide 5-Methoxy-2-[((4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl)sulfinyl]-benzimidazole EsoMeprazole related substance H431/41

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TIMTEC-BB SBB000219 5-Methoxybenzimidazole-2-thiol 5-METHOXY-2-THIOBENZIMIDAZOLE 5-METHOXY-2-BENZIMIDAZOLETHIOL 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE LABOTEST-BB LT01596137 2-Mercapoto-5-Methoxy-1H-benzimidazole Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole 5-Methoxy H 118/87 5-methoxy-2(1H)-benzimidazolinethione 2-Mercato-5-methoxy benzimidazole 5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole) 5-METHOXY-2-BENZIMIDAZOLEETHIOL 2-Mercapto-5-methoxy-1H-benzim 5-methoxy-2-thiohydroxy benzimidazole 5-Methoxy-2-thiobenzimidazole 99% 2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI) 5-methoxy-1H-benzoimidazole-2-thiol 5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE 5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE 5-Methoxy-1H-1,3-benzodiazole-2-thiol 5-Methoxy-1,3-dihydrobenzimidazole-2-thione 5-Methoxy-2-benzimidazolethiol ,99% 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+% 6-Methoxy-1H-benzimidazole-2-thiol 6-Methoxy-2-mercapto-1H-benzimidazole 5-Methoxy-2-mercapto 5-Methoxy-1H-benzimidazole-2-thiol 99% (S)-Omeprazole Intermediate 2 5-Methoxy-2-thio-1H-benzimidazole Omeprazole EP impurity-A (USP RC B) Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol) 2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole) 5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE Omeprazole RCB (USP) Esomeprazol EP Impurity A(Omeprazole EP Impurity A) 2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA ) OMEP IM-A EsoMeprazole related substance A EsoMeprazol iMpurity A OMeprazole IMpurity-A (EP) OMeprazole EP IMpurity A 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole 5-Methoxy-2-thio-1H-benzimidazole 99% 5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol) 5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A) 2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy- 2-Mercatto-5-Methoxy-1H-BenziMidazde 5-Methoxy-2-benziMidazolethiol 99% 5-Methoxy-2-mercaptobenzimidazole 5-Methoxybenzimidazole-2-thiol 5-Methoxy-2-mercaptobenzimidazole 5-Methoxy-2-benzimidazolethiol Esomeprazole Magnesium Trihydrate Imp. A (EP): 5-Methoxy-1H-benzimidazole-2-thiol OMeprazole Related CoMpound B Esomeprazole EP Impurity A