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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE structure

CAS No.: 37052-78-1

Chemical Name:: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Synonyms: 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219

CBNumber:: CB9313620

Molecular Formula:: C8H8N2OS

Molecular Weight:: 180.23

MDL Number:: MFCD00134581

MOL File:: 37052-78-1.mol

MSDS File:: SDS

Last updated:2026-01-13 11:26:47

Product description	Number	Pack Size	Price
5-Methoxy-2-benzimidazolethiol 99%	382485	5g	$57.8
Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard	1478480	15mg	$1290
2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T)	M1256	25g	$65
Omeprazole RCB (USP) Pharmaceutical Secondary Standard; Certified Reference Material	PHR1986	30mg	$673
5-Methoxy-2-mercaptobenzimidazole	M262760	500g	$460
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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Properties

Melting point	261-263 °C(lit.)
Boiling point	309.4±44.0 °C(Predicted)
Density	1.2425 (rough estimate)
vapor pressure	0.001Pa at 25℃
refractive index	1.5690 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Sparingly)
pka	10.13±0.30(Predicted)
form	Powder
color	Off-white to light yellow-brown
Water Solubility	insoluble
Sensitive	Air Sensitive
BRN	3605123
InChI	1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)
InChIKey	KOFBRZWVWJCLGM-UHFFFAOYSA-N
SMILES	COc1ccc2[nH]c(S)nc2c1
LogP	1.52-2.399
CAS DataBase Reference	37052-78-1(CAS DataBase Reference)
FDA UNII	143562LXX0
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P305+P351+P338

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-37-22

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29332900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Chronic 3
Skin Sens. 1

NFPA 704

	1
2		0

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	382485	5-Methoxy-2-benzimidazolethiol 99%	37052-78-1	5g	$57.8	2026-03-19	Buy
Sigma-Aldrich	1478480	Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard	37052-78-1	15mg	$1290	2026-03-19	Buy
TCI Chemical	M1256	2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T)	37052-78-1	25g	$65	2026-03-19	Buy
Sigma-Aldrich	PHR1986	Omeprazole RCB (USP) Pharmaceutical Secondary Standard; Certified Reference Material	37052-78-1	30mg	$673	2026-03-19	Buy
TRC	M262760	5-Methoxy-2-mercaptobenzimidazole	37052-78-1	500g	$460	2021-12-16	Buy

Product number	Packaging	Price	Buy
382485	5g	$57.8	Buy
1478480	15mg	$1290	Buy
M1256	25g	$65	Buy
PHR1986	30mg	$673	Buy
M262760	500g	$460	Buy

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Uses,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ²P:P′;1:3κ²P:P′;2:3κ²P:P′-di-μ-bromido-1:2κ⁴Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Ufiprazole Omeprazole 2-[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(2-nitrophenyl)acetamide

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Suppliers

Global( 774)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5237	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Hebei Longbang Technology Co., LTD	+86-18633929156	admin@hblongbang.com	China	972	58
HebeiShuoshengImportandExportco.,Ltd	+86-18532138899	L18532138899@163.com	China	939	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29823	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
Hebei Longbang Technology Co., LTD	58
HebeiShuoshengImportandExportco.,Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58

View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-14	5-methyoxy-2-mercapto Benzimidazole 37052-78-1	US $0.00 / Kg/Drum	1KG	97%-102%	10 tons	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-14	5-Methoxy-2-mercaptobenzimidazole 37052-78-1	US $0.00 / Kg/Drum	1ASSAYS	99%	50mt	Jinan Finer Chemical Co., Ltd
2026-03-20	2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

5-methyoxy-2-mercapto Benzimidazole
37052-78-1
US $0.00 / Kg/Drum
97%-102%
WUHAN FORTUNA CHEMICAL CO., LTD

5-Methoxy-2-mercaptobenzimidazole
37052-78-1
US $0.00 / Kg/Drum
99%
Jinan Finer Chemical Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Spectrum

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)MS 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)¹HNMR 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)¹³CNMR 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR1 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR2 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)Raman

37052-78-1(2-MERCAPTO-5-METHOXYBENZIMIDAZOLE)Related Search:

2-Ethylhexyl mercaptoacetate Thioglycolic acid 2-Mercaptobenzimidazole 2-Methoxyethanol Benzimidazole

2-Methylbenzimidazole 3-Mercaptopropionic acid Ufiprazole OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Calcium thioglycolate

Omeprazole 5-METHOXY-2-[((4-METHOXY-3,5-DIMETHYL-1-OXIDO-2-PYRIDINYL)METHYL)SULFINYL]-BENZIMIDAZOLE Esomeprazole Impurity 3 (S)-4-Desmethoxy-4-chloro Omeprazole 4-Hydroxy Omeprazole

Omeprazole EP Impurity F Omeprazole Sulfone N-Oxide EsoMeprazole related substance H431/41

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5-Methoxye-2-mercaplobenzinidazole TIMTEC-BB SBB000219 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL 5-Methoxybenzimidazole-2-thiol 5-METHOXY-2-THIOBENZIMIDAZOLE 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE 5-METHOXY-2-BENZIMIDAZOLETHIOL 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE LABOTEST-BB LT01596137 2-Mercapoto-5-Methoxy-1H-benzimidazole Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole 5-Methoxy H 118/87 5-methoxy-2(1H)-benzimidazolinethione 2-Mercato-5-methoxy benzimidazole 5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole) 5-METHOXY-2-BENZIMIDAZOLEETHIOL 2-Mercapto-5-methoxy-1H-benzim 5-methoxy-2-thiohydroxy benzimidazole 5-Methoxy-2-thiobenzimidazole 99% 2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI) 5-methoxy-1H-benzoimidazole-2-thiol 5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE 5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE 5-Methoxy-1H-1,3-benzodiazole-2-thiol 5-Methoxy-1,3-dihydrobenzimidazole-2-thione 5-Methoxy-2-benzimidazolethiol ,99% 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+% 6-Methoxy-1H-benzimidazole-2-thiol 6-Methoxy-2-mercapto-1H-benzimidazole 5-Methoxy-2-mercapto 5-Methoxy-1H-benzimidazole-2-thiol 99% (S)-Omeprazole Intermediate 2 5-Methoxy-2-thio-1H-benzimidazole Omeprazole EP impurity-A (USP RC B) Esomeprazole impurity A Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol) 2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole) 5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE Omeprazole RCB (USP) Esomeprazol EP Impurity A(Omeprazole EP Impurity A) 2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA ) OMEP IM-A Omeprazole Impurity A EsoMeprazole related substance A EsoMeprazol iMpurity A OMeprazole IMpurity-A (EP) OMeprazole EP IMpurity A 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole 5-Methoxy-2-thio-1H-benzimidazole 99% 5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol) 5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A) 2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy- 2-Mercatto-5-Methoxy-1H-BenziMidazde