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(R)-(-)-Glycidyl nosylate

CAS No.
115314-17-5
Chemical Name:
(R)-(-)-Glycidyl nosylate
Synonyms
(R)-Oxiran-2-ylMethyl 3-nitrobenzenesulfonate;(R)-GLYCIDYL 3-NITROBENZENESULFONATE;Landiolol Impurity 1;Landiolol impurity78;(R)-GLYCIDYL NOSYLATE;Landiolol Impurity 73;(R)-Glycidil-4-Nosylate;(R)-(-)-GLYCIDYL NOSYLATE;(R)-(-)-GLYCIDYL-3-NOSYLATE;(R)-Glycidyl Nosylate,99%e.e.
CBNumber:
CB9329397
Molecular Formula:
C9H9NO6S
Molecular Weight:
259.24
MDL Number:
MFCD00013436
MOL File:
115314-17-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:17:00
Product description Number Pack Size Price
(R)-Glycidyl 3-Nitrobenzenesulfonate >98.0%(GC) G0286 5g $67
(R)-Glycidyl 3-Nitrobenzenesulfonate >98.0%(GC) G0286 25g $225
(R)-(-)-Glycidyl Nosylate TRC-G615975-5G 5g $65
(R)-(-)-Glycidyl Nosylate TRC-G615975-25G 25g $142
(R)-(-)-Glycidyl Nosylate 012925 1g $403
More product size

(R)-(-)-Glycidyl nosylate Properties

Melting point 59-63 °C
alpha -21.5 º (c=2, CHCl3)
Boiling point 432.2±20.0 °C(Predicted)
Density 1.5881 (rough estimate)
refractive index 1.5270 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly)
form Crystalline Needles or Powder
color Slightly yellow
optical activity -22.001°(C=1.00 g/100ml, CHCL3)
InChI InChI=1S/C9H9NO6S/c11-10(12)7-2-1-3-9(4-7)17(13,14)16-6-8-5-15-8/h1-4,8H,5-6H2/t8-/m1/s1
InChIKey AIHIHVZYAAMDPM-MRVPVSSYSA-N
SMILES C1(S(OC[C@H]2CO2)(=O)=O)=CC=CC([N+]([O-])=O)=C1
CAS DataBase Reference 115314-17-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)Flame (GHS02)
GHS07,GHS08,GHS02
Signal word  Danger
Hazard statements  H315-H319-H341-H228
Precautionary statements  P501-P202-P240-P210-P201-P241-P264-P280-P302+P352-P370+P378-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-36
RIDADR  UN 1325 4.1/PG II
RTECS  DB7192000
HazardClass  4.1
PackingGroup  II
HS Code  29209090
NFPA 704
1
1 1

(R)-(-)-Glycidyl nosylate price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical G0286 (R)-Glycidyl 3-Nitrobenzenesulfonate >98.0%(GC) 115314-17-5 5g $67 2026-04-30 Buy
TCI Chemical G0286 (R)-Glycidyl 3-Nitrobenzenesulfonate >98.0%(GC) 115314-17-5 25g $225 2026-04-30 Buy
TRC TRC-G615975-5G (R)-(-)-Glycidyl Nosylate 115314-17-5 5g $65 2026-06-03 Buy
TRC TRC-G615975-25G (R)-(-)-Glycidyl Nosylate 115314-17-5 25g $142 2026-06-03 Buy
Usbiological 012925 (R)-(-)-Glycidyl Nosylate 115314-17-5 1g $403 2026-06-03 Buy
Product number Packaging Price Buy
G0286 5g $67 Buy
G0286 25g $225 Buy
TRC-G615975-5G 5g $65 Buy
TRC-G615975-25G 25g $142 Buy
012925 1g $403 Buy

(R)-(-)-Glycidyl nosylate Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

(R)-(-)-Glycidyl Nosylate (cas# 115314-17-5) is a compound useful in organic synthesis.

Synthesis

3-Nitrobenzenesulfonyl chloride

121-51-7

(S)-Oxiranemethanol

60456-23-7

(S)-(+)-Glycidyl nosylate

115314-14-2

Preparation of Compound 3: To an anhydrous dichloromethane (10 mL) and triethylamine (1.5 mL, 10 mmol) solution of (S)-oxiran-2-ylmethanol (220 mg, 3.0 mmol) that had been cooled to 0 °C (ice bath), 3-nitrobenzenesulfonyl chloride (730 mg, 3.3 mmol) was added in batches. The resulting brown solution was stirred at 0 °C for 1 h, followed by slow warming to room temperature. The progress of the reaction was monitored by TLC every 15 min until (S)-oxiran-2-ylmethanol was completely consumed. Upon completion of the reaction, the reaction was quenched by the addition of crushed ice (1-2 g). The reaction mixture was transferred to a dispensing funnel and partitioned with dichloromethane (20 mL) and water (10 mL). The organic layer was washed sequentially with saturated aqueous NaHCO3 (10 mL x 3) and brine (10 mL x 3), followed by drying with anhydrous Na2SO4. After filtration and concentration, the residue was purified by fast column chromatography to afford (S)-(+)-m-nitrobenzenesulfonic acid glycidyl ester (Compound 3) as a brown solid (710 mg, 92%).1H NMR (400 MHz, CDCl3) δ 8.77 (s, 1H), 8.54 (d, J=8.1 Hz, 1H), 8.28 (d, J=7.9 Hz , 1H), 4.50 (d, J=11.5Hz, 1H), 4.04 (dd, J1=4.9Hz, J2=1.5Hz, 1H), 3.23 (d, J=1.8Hz, 1H), 2.85 (dd, J1=4.0Hz, J2=2.0Hz, 1H), 2.64 (dd, J1=2.4Hz, J2=2.0Hz, 1H) 1H); 13C NMR (100 MHz, CDCl3) δ 148.19, 137.92, 133.32, 130.81, 128.39, 123.16, 71.69, 48.64, 44.42.

References

[1] Patent: US2009/182011, 2009, A1. Location in patent: Page/Page column 13
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 9, p. 656 - 661
[3] Tetrahedron, 2009, vol. 65, # 31, p. 5984 - 5989
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 8, p. 2948 - 2950
[5] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 17, p. 4792 - 4802

(R)-(-)-Glycidyl nosylate Preparation Products And Raw materials

Global( 250)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88298848 info@edengenechem.com China 2165 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Jinan Liheng Biotechnology Co., Ltd.
15865262812 info@lihengpharm.com CHINA 938 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9996 58

View Lastest Price from (R)-(-)-Glycidyl nosylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-Glycidyl 3-nitrobenzenesulfonate pictures 2026-03-03 (R)-Glycidyl 3-nitrobenzenesulfonate
115314-17-5
10kg 99%min 10 tons Hangzhou Verychem Science And Technology Co.Ltd
(R)-(-)-Glycidyl nosylate pictures 2025-09-25 (R)-(-)-Glycidyl nosylate
115314-17-5
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
(R)-(-)-Glycidyl nosylate  pictures 2020-02-26 (R)-(-)-Glycidyl nosylate
115314-17-5
1KG 99.0% 100 tons Shaanxi Dideu Medichem Co. Ltd

(R)-(-)-Glycidyl nosylate Spectrum

(R)-Glycidyl Nosylate,99%e.e. 3-nitro-,oxiranylmethylester,(r)-benzenesulfonicaci oxiranylmethyl(r)-3-nitrobenzenesulfonate (R)-(-)-OXIRANE-2-METHANOL 3-NITROBENZENESULFONATE (R)-(-)-GLYCIDYL NOSYLATE (R)-GLYCIDYL NOSYLATE (R)-(-)-GLYCIDYL-3-NITROBENZENESULFONATE (R) glycidyl nosylate = (R)-oxiran-2-ylmethyl 3-nitrobenzenesulfonate Landiolol Impurity 1 (R)-(-)-GLYCIDYL-3-NOSYLATE (R)-2,3-EPOXY-1-PROPYL-3-NITROBENZENESULFONATE BENZENESULFONIC ACID, 3-NITRO-, (2R)-OXIRANYLMETHYL ESTER 3-NITROBENZENESULFONIC ACID (R)-GLYCIDYL ESTER (2R)-(-)-GLYCIDYL-3-NITROBENZENESULFONATE (2R)-(-)-Glycidyl-3-nitrobenzenesulphonate (2R)-(-)-GLYCIDYL 3-NITROBENZENE- (R)-(-)-Glycidyl 3-nitrobenzenesulfonate, (R)-(-)-Oxirane-2-methanol 3-nitrobenzenesulfonate [(2R)-Oxiran-2-yl]methyl 3-nitrobenzenesulfonate Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester, (R) (R)-(-)-Glycidyl nosylate,98% R-Glycidyl-3-Nitrobenzenesulfo (R)-(-)-GLYCIDYL3-NITRO-BENZENESULPHONATE BENZENESULFONIC ACID, 3-NITRO-(2R)-2-OXIRANYL-METHYL ESTER (R)-Glycidil-4-Nosylate (2R)-OxiranylMethyl 3-Nitrobenzenesulfonate (R)-Glycidol 3-Nitrobenzenesulfonate (R)-Glycidyl3-Nitrobenzenesulfonate> (R)-(-)-Glycidyl nosylate ISO 9001:2015 REACH 3-nitro-Benzenesulfonic acid (2R)-2-oxiranylmethyl ester Landiolol Impurity 73 Landiolol impurity78 3-Nitro-benzenesulfonic acid (2R)-oxiran-2-ylmethyl ester (R)-GLYCIDYL 3-NITROBENZENESULFONATE (R)-Oxiran-2-ylMethyl 3-nitrobenzenesulfonate 115314-17-5 C9H9NO6S1 Asymmetric Synthesis Epoxides Organic Building Blocks Chiral Building Blocks chiral CHIRAL COMPOUNDS Chiral Reagents Heterocycles Sulfur & Selenium Compounds