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2-(1-Adamantyl)-4-bromophenol

2-(1-Adamantyl)-4-bromophenol structure

CAS No.: 104224-68-2

Chemical Name:: 2-(1-Adamantyl)-4-bromophenol

Synonyms: 2-(1-Adamantyl)-4-br;4-BROMO-2-ADAMANTYL PHENOL;2-ADAMANTANE-4-BROMOANISOLE;(2-ADAMANTYL)-4-BROMOPHENOL;2-(2-adamantyl)-4-bromophenol;2-(1-ADAMANTYL)-4-BROMOPHENOL;2-(Adamantan-1-yl)-4-bromophenol;2-(Adamantan-1-yl)-4-bromophenol 98%;2-(1-Adamantyl)-4-bromophenol (Adapalene);Phenol, 4-bromo-2-tricyclo[3.3.1.13,7]dec-1-yl-

CBNumber:: CB9339345

Molecular Formula:: C16H19BrO

Molecular Weight:: 307.23

MDL Number:: MFCD00169077

MOL File:: 104224-68-2.mol

MSDS File:: SDS

Last updated:2026-05-28 05:21:10

Product description	Number	Pack Size	Price
2-(1-Adamantyl)-4-bromophenol	FA70832	10g	$194.7
2-(1-Adamantyl)-4-bromophenol	FA70832	25g	$389.5
2-(1-Adamantyl)-4-bromophenol	FA70832	50g	$649
2-(1-Adamantyl)-4-bromophenol	FA70832	100g	$1038
2-(1-Adamantyl)-4-bromophenol	FA70832	250g	$2077.5
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2-(1-Adamantyl)-4-bromophenol Properties

Melting point	137-141
Boiling point	392.0±35.0 °C(Predicted)
Density	1.442±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	9.56±0.43(Predicted)
Appearance	Off-white to light yellow Solid
InChI	InChI=1S/C16H19BrO/c17-13-1-2-15(18)14(6-13)16-7-10-3-11(8-16)5-12(4-10)9-16/h1-2,6,10-12,18H,3-5,7-9H2
InChIKey	NYJXKHIVLGWPCF-UHFFFAOYSA-N
SMILES	C1(O)=CC=C(Br)C=C1C12CC3CC(CC(C3)C1)C2
CAS DataBase Reference	104224-68-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H317-H319
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xi
Hazard Note	Irritant
HS Code	2907290090

2-(1-Adamantyl)-4-bromophenol price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FA70832	2-(1-Adamantyl)-4-bromophenol	104224-68-2	10g	$194.7	2026-06-04	Buy
Biosynth	FA70832	2-(1-Adamantyl)-4-bromophenol	104224-68-2	25g	$389.5	2026-06-04	Buy
Biosynth	FA70832	2-(1-Adamantyl)-4-bromophenol	104224-68-2	50g	$649	2026-06-04	Buy
Biosynth	FA70832	2-(1-Adamantyl)-4-bromophenol	104224-68-2	100g	$1038	2026-06-04	Buy
Biosynth	FA70832	2-(1-Adamantyl)-4-bromophenol	104224-68-2	250g	$2077.5	2026-06-04	Buy

Product number	Packaging	Price	Buy
FA70832	10g	$194.7	Buy
FA70832	25g	$389.5	Buy
FA70832	50g	$649	Buy
FA70832	100g	$1038	Buy
FA70832	250g	$2077.5	Buy

2-(1-Adamantyl)-4-bromophenol Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

2-(Adamantan-1-yl)-4-bromophenol is an intermediate in the synthesis of Adapalene (A225000), a retinoid selective for retinoic acid receptor (RAR) subtypes β and γ; an antiacne agent.

Synthesis

106-41-2

768-95-6

104224-68-2

Preparation of 2-(1-adamantyl)-4-bromophenol (III): 4-bromophenol (10.0 g, 57.8 mmol) was dissolved in methanesulfonic acid (15 mL) with 1-adamantanol (8.78 g, 57.76 mmol), and the reaction was stirred for 3 hr at 70 °C. After completion of the reaction, the mixture was cooled to room temperature and diluted with deionized water (50 mL). The precipitated white solid was collected by filtration, washed several times with deionized water and subsequently dried to afford the target product 2-(1-adamantyl)-4-bromophenol (III). [Yield: 17 g, Yield: 97%]

References

[1] Bioorganic Chemistry, 2011, vol. 39, # 4, p. 151 - 158
[2] RSC Advances, 2016, vol. 6, # 73, p. 68560 - 68567
[3] Organic Process Research and Development, 2006, vol. 10, # 2, p. 285 - 288
[4] Beilstein Journal of Organic Chemistry, 2012, vol. 8, p. 227 - 233
[5] Patent: WO2007/125542, 2007, A2. Location in patent: Page/Page column 13-14

2-(1-Adamantyl)-4-bromophenol Preparation Products And Raw materials

Raw materials

4-Bromophenol 1-Adamantanol

Preparation Products

1-(5-Bromo-2-methoxy-phenyl)adamantane

2-(1-Adamantyl)-4-bromophenol Suppliers

Global( 162)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexcon Pharmatechs Ltd.	+86-0755-89396905 +86-18025329037	admin@nexconn.com	China	6062	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10817	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9609	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2777	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58

Supplier	Advantage
Shenzhen Nexcon Pharmatechs Ltd.	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
Longyan Tianhua Biological Technology Co., Ltd	58
Dideu Industries Group Limited	58
BOC Sciences	58

View Lastest Price from 2-(1-Adamantyl)-4-bromophenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-03	2-(1-Adamantyl)-4-bromophenol 104224-68-2		1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.
2025-11-18	2-(1-Adamantyl)-4-bromophenol 104224-68-2	$1.10	1g	99.0% Min	100 Tons	Dideu Industries Group Limited
2025-06-04	2-(1-Adamantyl)-4-bromophenol 104224-68-2		10g	98%+	100kgs per Month	Shanghai Qyubiotech Co., Ltd.

2-(1-Adamantyl)-4-bromophenol
104224-68-2
98%
Shenzhen Nexcon Pharmatechs Ltd.

2-(1-Adamantyl)-4-bromophenol
104224-68-2
$1.10
99.0% Min
Dideu Industries Group Limited

2-(1-Adamantyl)-4-bromophenol
104224-68-2
98%+
Shanghai Qyubiotech Co., Ltd.

104224-68-2(2-(1-Adamantyl)-4-bromophenol)Related Search:

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1-(5-Bromo-2-methoxy-phenyl)adamantane 1-Bromo-3-n-hexylbenzene, 97+% 1-Phenyladamantane 3-tert-butylbromobenzene Adapalene

4-Bromoanisole Adamantane bromophenol 4-(1-ADAMANTYL)-2-BROMOPHENOL 2-(1-Adamantyl)-4-bromophenol

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2-(1-Adamantyl)-4-bromophenol (Adapalene) 2-(1-Adamantyl)-4-br 4-BROMO-2-ADAMANTYL PHENOL 2-(2-adamantyl)-4-bromophenol (2-ADAMANTYL)-4-BROMOPHENOL 2-(1-ADAMANTYL)-4-BROMOPHENOL 2-(Adamantan-1-yl)-4-bromophenol 2-ADAMANTANE-4-BROMOANISOLE 2-(Adamantan-1-yl)-4-bromophenol 98% 2-(1-Adamantyl)-4-bromophenol CAS NO: 104224-68-2 Phenol, 4-bromo-2-tricyclo[3.3.1.13,7]dec-1-yl- 2-(1-Adamantyl)-4-bromophenol ISO 9001：2015 REACH 104224-68-2 116437-98-8 C16H19BrO Adamantane derivatives Phenol&Thiophenol&Mercaptan APIs Intermediate blocks Bromides