6-Methylpyridine-3-boronic Acid
- CAS No.
- 659742-21-9
- Chemical Name:
- 6-Methylpyridine-3-boronic Acid
- Synonyms
- (6-METHYLPYRIDIN-3-YL)BORONIC ACID;2-METHYLPYRIDINE-5-BORONIC ACID;2-Methyl-5-boronic acid;2-Picoline-5-boronicaci;2-picolin-5-boronic acid;2-Methyl-5-pyridine acid;2-Picoline-5-boronic acid;6-Methylpyridine-3-Boronic;2-methyl-5-pydineboronic acid;2-METHYL-5-PYRIDINEBORONIC ACID
- CBNumber:
- CB9380574
- Molecular Formula:
- C6H8BNO2
- Molecular Weight:
- 136.94
- MDL Number:
- MFCD06801736
- MOL File:
- 659742-21-9.mol
- MSDS File:
- SDS
| Melting point | 128-130°C |
|---|---|
| Boiling point | 294.7±42.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 4.27±0.10(Predicted) |
| color | White to pale brown |
| Stability | Hygroscopic |
| InChI | 1S/C6H8BNO2/c1-5-2-3-6(4-8-5)7(9)10/h2-4,9-10H,1H3 |
| InChIKey | MZUSCPDSQJSBSY-UHFFFAOYSA-N |
| SMILES | Cc1ccc(cn1)B(O)O |
| CAS DataBase Reference | 659742-21-9(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
6-Methylpyridine-3-boronic Acid price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 748404 | 6-Methylpyridine-3-boronic acid | 659742-21-9 | 1g | $258 | 2026-04-30 | Buy |
| Sigma-Aldrich | 748404 | 6-Methylpyridine-3-boronic acid | 659742-21-9 | 500mg | $130 | 2023-01-07 | Buy |
| Usbiological | 281834 | 2-Methylpyridine-5-boronic acid | 659742-21-9 | 500mg | $453 | 2026-06-03 | Buy |
| Usbiological | 281834 | 2-Methylpyridine-5-boronic acid | 659742-21-9 | 1g | $638 | 2026-06-03 | Buy |
| Usbiological | 281834 | 2-Methylpyridine-5-boronic acid | 659742-21-9 | 2g | $871 | 2026-06-03 | Buy |
6-Methylpyridine-3-boronic Acid Chemical Properties,Uses,Production
Chemical Properties
White to off-white solid
Uses
6-Methylpyridine-3-boronic Acid is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors.
Uses
suzuki reaction
Synthesis
111770-91-3
73183-34-3
659742-21-9
General procedure for the synthesis of 6-methyl-3-pyridineboronic acid from 6-methyl-3-pyridinol trifluoromethanesulfonate and bis(pinacolato)diboronate: 6-methyl-3-pyridinol trifluoromethanesulfonate (4.6 mmol) was dissolved in acetonitrile (30 mL) and transferred to a 5 mL microwave reaction tube. To this solution was added 1.5 equivalents of bis(pinacolato)diboron (6.9 mmol; 1.71 g). The mixture was stirred on a magnetic stirrer until complete dissolution. Subsequently, potassium acetate (13.8 mmol; 1.35 g) and [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride (98 mg, 0.03 mol%) were added to the mixture. The reaction mixture was placed in a microwave reactor and heated at 160°C for 2 x 600 seconds. Upon completion of the reaction (monitored by LC-MS), the acetonitrile was removed by evaporation to give a black solid. The solid was dissolved in DMSO and purified by HPLC to give the final target product 6-methyl-3-pyridineboronic acid (580 mg, 92% yield; 4.2 mmol). Mass spectral data: MH+ = 138.
References
[1] Patent: WO2005/32493, 2005, A2. Location in patent: Page/Page column 40-41
6-Methylpyridine-3-boronic Acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 28-83379370 13880556291 | tcy@tcypharm.com | China | 509 | 57 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Lastest Price from 6-Methylpyridine-3-boronic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | (6-Methylpyridin-3-yl)boronic acid
659742-21-9
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2019-07-06 | 6-Methylpyridine-3-boronic Acid
659742-21-9
|
$1.00 | 1KG | 97%-99% | 1kg;5kg;100kg | Career Henan Chemical Co |
-
- (6-Methylpyridin-3-yl)boronic acid
659742-21-9
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 6-Methylpyridine-3-boronic Acid
659742-21-9
- $1.00
- 97%-99%
- Career Henan Chemical Co
659742-21-9(6-Methylpyridine-3-boronic Acid)Related Search:
1of4
