2-Methylpyridine-4-boronic acid
- CAS No.
- 579476-63-4
- Chemical Name:
- 2-Methylpyridine-4-boronic acid
- Synonyms
- (2-METHYLPYRIDIN-4-YL)BORONIC ACID;2-PICOLINE-4-BORONIC ACID;4-Borono-2-methylpyridine;2-METHYL-4-PYRIDINEBORIC ACID;2-Methylpyridine-4-boronicaci;2-METHYLPYRIDINE-4-BORONIC ACID;2-METHYL-4-PYRIDINEBORONIC ACID;2-METHYL-4-PYRIDINYLBORONIC ACID;(2-Methylpyridine-4-yl)boronic acid;2-Methylpyridin-4-yl-4-boronic acid
- CBNumber:
- CB9145397
- Molecular Formula:
- C6H8BNO2
- Molecular Weight:
- 136.94
- MDL Number:
- MFCD03095364
- MOL File:
- 579476-63-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 311.2±44.0 °C(Predicted) |
|---|---|
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | crystalline powder |
| pka | 7+-.0.10(Predicted) |
| color | Cream |
| CAS DataBase Reference | 579476-63-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
2-Methylpyridine-4-boronic acid price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2912 | (2-Methylpyridin-4-yl)boronic Acid (contains varying amounts of Anhydride) | 579476-63-4 | 1G | $56 | 2026-04-30 | Buy |
| TCI Chemical | M2912 | (2-Methylpyridin-4-yl)boronic Acid (contains varying amounts of Anhydride) | 579476-63-4 | 5G | $225 | 2026-04-30 | Buy |
| Biosynth | FM75225 | 2-Methylpyridine-4-boronic acid | 579476-63-4 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FM75225 | 2-Methylpyridine-4-boronic acid | 579476-63-4 | 2g | $253.96 | 2026-06-04 | Buy |
| Biosynth | FM75225 | 2-Methylpyridine-4-boronic acid | 579476-63-4 | 5g | $362.8 | 2026-06-04 | Buy |
2-Methylpyridine-4-boronic acid Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powder
Uses
suzuki reaction
Uses
(2-Methylpyridin-4-yl)boronic Acid (CAS# 579476-63-4) is used as a reagent in the preparation of dihydro-phenylquinazlinone derivatives as encephalitic alphaviruses inhibitors useful in the treatment of viral infections.
Synthesis
Under nitrogen protection, 4-bromo-2-methylpyridine, a certain proportion of tributyl borate and tetrahydrofuran were added to a four-necked flask, and the temperature was lowered to -68-70. Add n-butyllithium dropwise into the quartet until the solution was yellow. The solution was kept warm for 1 h. Dilute HCl was then added immediately to hydrolyze the solution. The solution first produced precipitation, with the gradual disappearance of precipitation, adjust the pH value of the system to 1. To the solution of NaOH solution with a mass fraction of 25% was added dropwise to the pH value of 13, stirring for 1 h. Separation of the liquid, the organic phase was extracted with 15 mL of NaOH with a mass fraction of 10%, and the aqueous phase was combined, and the alkaline solution was extracted with 15 mL of THF for 2 times, respectively. The obtained alkaline solution was adjusted to pH with dilute HCl, turbidity was generated at the beginning, flocculent appeared slowly, and the pH was adjusted to 5.0. The aqueous phase was extracted with 70 mL of tetrahydrofuran, and the organic phase was spin-dried and purified to obtain the product 2-methyl-4-pyridineboronic acid in 82.20% yield.
2-Methylpyridine-4-boronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from 2-Methylpyridine-4-boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2-Methylpyridine-4-boronic acid
579476-63-4
|
$1.00 | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- 2-Methylpyridine-4-boronic acid
579476-63-4
- $1.00
- 95%-99%
- Career Henan Chemical Co
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