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1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Structure
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile structure
CAS No.
28049-61-8
Chemical Name:
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
Synonyms
1-(4-Chlorophenyl)cyclobutane-1-carbonitrile;SIBU-1;NSC 154613;Sibutramine Impurity F;Sibutramine Impurity 34;Sibutramine Impurity 13;1-(4-Chlorophenyl)cyclobutanecarbon;1-CYANO-1-(4-CHLOROPHENYL)CYCLOBUTANE;1-(4-chlorophenyl)cyclobutancarbonitrile;1-(4-CHLOROPHENYL)CYCLOBUTANECARBONITRILE
CBNumber:
CB9433362
Molecular Formula:
C11H10ClN
Molecular Weight:
191.66
MDL Number:
MFCD00065239
MOL File:
28049-61-8.mol
MSDS File:
SDS
Last updated:2026-05-28 04:37:32
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1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Properties

Boiling point 295 °C (lit.)
Density 1.137 g/mL at 25 °C (lit.)
refractive index n20/D 1.548(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
color Clear Colourless to Pale Yellow
InChI InChI=1S/C11H10ClN/c12-10-4-2-9(3-5-10)11(8-13)6-1-7-11/h2-5H,1,6-7H2
InChIKey XQONXPWVIZZJIL-UHFFFAOYSA-N
SMILES C1(C2=CC=C(Cl)C=C2)(C#N)CCC1
CAS DataBase Reference 28049-61-8(CAS DataBase Reference)
FDA UNII 35U5QL7HSY
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  36-36/37/39-26
RIDADR  UN3276
WGK Germany  3
HazardClass  6.1
PackingGroup  III
HS Code  29269095
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
NFPA 704
1
2 0

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 160008 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile 97% 28049-61-8 25g $324 2026-04-30 Buy
TCI Chemical C3161 1-(4-Chlorophenyl)cyclobutanecarbonitrile >98.0%(GC) 28049-61-8 5g $371 2026-04-30 Buy
TCI Chemical C3161 1-(4-Chlorophenyl)cyclobutanecarbonitrile >98.0%(GC) 28049-61-8 25g $1104 2026-04-30 Buy
Usbiological 268491 1-(4-Chlorophenyl)cyclobutane carbonitrile 28049-61-8 250mg $425 2026-06-03 Buy
Usbiological 268491 1-(4-Chlorophenyl)cyclobutane carbonitrile 28049-61-8 500mg $644 2026-06-03 Buy
Product number Packaging Price Buy
160008 25g $324 Buy
C3161 5g $371 Buy
C3161 25g $1104 Buy
268491 250mg $425 Buy
268491 500mg $644 Buy

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Chemical Properties, Uses, Production

Chemical Properties

Colourless Oil

Uses

An intermediate in the preparation of Sibutramine and respective metabolites

Uses

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile (1-(4-chlorophenyl)-1-cyanocyclobutane) can be used in the synthesis of pharmacologically active metabolites of the anti-obesity drug-sibutramine.

General Description

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile is also referred as 1-(4-chlorophenyl)-1-cyanocyclobutane.

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Suppliers

Global Suppliers ( 206)
Supplier Tel Email Country ProdList Advantage
Beijing Bankchem Pharmatech Co.,Ltd. 010-80236392 17600588818 bankchem@163.com China 247 58
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1996 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China Langchem Inc. 0086-21-58956006 China 7798 57
Supplier Advantage
Beijing Bankchem Pharmatech Co.,Ltd. 58
Chengdu Forest Science and Technology Development Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
Energy Chemical 61
Adamas Reagent, Ltd. 59
Shanghai Longsheng chemical Co.,Ltd. 59
Chemsky（shanghai）International Co.,Ltd. 50
China Langchem Inc. 57

View Latest Price from 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile pictures 2026-09-02 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
28049-61-8
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile pictures 2020-01-13 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
28049-61-8
 $9.80 1KG ≥98% 20 tons Career Henan Chemical Co

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Spectrum

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile(28049-61-8)1HNMR

28049-61-8 (1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile) Related Search:

1-Chloro-2-methylpropane Cyclopropane 2-Chloro-2-methylpropane Chlorodimethylphenylsilane 1-Chlorobutane
2-Chloro-3-cyanopyridine Triphenylmethyl Chloride Chlorophenylsilane 4-Chloro-alpha,alpha-di-2-propenylbenzeneacetonitrile 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutan-1-one
N-Formyl N,N-Didesmethyl Sibutramine tert-Butylchlorodiphenylsilane 1-Phenylcyclobutanecarbonitrile 3-Methylenecyclobutanecarbonitrile 1-(3,4-Dichlorophenyl)cyclobutanecarbonitrile
3-Oxo-cyclobutanecarbonitrile 1-Cyanocyclobutanecarboxylic acid ethyl ester trans-Cyclobutane-1,2-dicarbonitrile

1of4

CYCLOBUTANECARBONITRILE, 1-(4-CHLOROPHENYL) CYCLOBUTANECARBONITRILE, 1-(4-CHLOROPHENYL)(INTERMEDIATE OF SIBUTRAMINE) 1-CYANO-1-(4-CHLOROPHENYL)CYCLOBUTANE 1-(4-CHLOROPHENYL)-1-CYCLOBUTANECARBONITRILE 1-(4-CHLOROPHENYL)CYCLOBUTANECARBONITRILE NSC 154613 SIBU-1 Sibutramine Impurity F Sibutramine EP Impurity F (1-(4-Chlorophenyl)cyclobutan 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile,97% 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrileSibu-1 1-(p-Chlorophenyl)cyclobutanecarbonitrile CYCLOBUTANECARBONITRILE, 1-(4-CHLOROPHENYL)/FOR SIBUTRAMINE 1-(4-chlorophenyl)cyclobutancarbonitrile 1-(4-CHLOROPHENYL)-1-CYCLOBUTANECARBONITRILE 97% 1-(4-Chlorophenyl)cyclobutanecarbon Sibutramine Impurity 34 Sibutramine Hydrochloride Monohydrate EP Impurity F Sibutramine Hydrochloride Monohydrate Impurity F Sibutramine Impurity 13 1-(4-Chlorophenyl)cyclobutane-1-carbonitrile 28049-61-8 28049-61-9 C11H10ClN ClC6H4C4H6CN C10 to C27 Building Blocks Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds Aromatics Intermediates & Fine Chemicals Pharmaceuticals C10 to C27 Cyanides/Nitriles Nitrogen Compounds