AT-130 (AT130)
- CAS No.
- 211364-06-6
- Chemical Name:
- AT-130 (AT130)
- Synonyms
- AT-130;AT-130 (AT130);AT-130, 10 mM in DMSO;Benzamide, N-[(1E)-2-bromo-2-(2-methoxyphenyl)-1-(1-piperidinylcarbonyl)ethenyl]-4-nitro-;(E)-N-(1-Bromo-1-(2-methoxyphenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl)-4-nitrobenzamide;RNA,HBV,AT-130,Huh-7,DNA/RNA Synthesis,rtM204I,inhibit,rtL180M,AT130,Inhibitor,Hepatitis B virus,HepG2,core
- CBNumber:
- CB94844489
- Molecular Formula:
- C22H22BrN3O5
- Molecular Weight:
- 488.33
- MDL Number:
- MFCD30533282
- MOL File:
- 211364-06-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
AT-130 (AT130) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35453 | AT-130 ≥98% | 211364-06-6 | 1mg | $57 | 2026-04-30 | Buy |
| Cayman Chemical | 35453 | AT-130 ≥98% | 211364-06-6 | 5mg | $238 | 2026-04-30 | Buy |
| Cayman Chemical | 35453 | AT-130 ≥98% | 211364-06-6 | 10mg | $390 | 2026-04-30 | Buy |
| Cayman Chemical | 35453 | AT-130 ≥98% | 211364-06-6 | 25mg | $834 | 2026-04-30 | Buy |
| Biosynth | LIA36406 | AT-130 | 211364-06-6 | 25mg | $1091.5 | 2026-06-04 | Buy |
AT-130 (AT130) Chemical Properties, Uses, Production
Uses
AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells[1][2][3].
References
[1] William E Delaney 4th, et al. Phenylpropenamide derivatives AT-61 and AT-130 inhibit replication of wild-type and lamivudine-resistant strains of hepatitis B virus in vitro. Antimicrob Agents Chemother. 2002 Sep;46(9):3057-60. DOI:10.1128/AAC.46.9.3057-3060.2002
[2] R B Perni , et al. Phenylpropenamide derivatives as inhibitors of hepatitis B virus replication. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2687-90. DOI:10.1016/s0960-894x(00)00544-8
[3] J J Feld, et al. The phenylpropenamide derivative AT-130 blocks HBV replication at the level of viral RNA packaging. Antiviral Res. 2007 Nov;76(2):168-77. DOI:10.1016/j.antiviral.2007.06.014
AT-130 (AT130) Preparation Products And Raw materials
Raw materials
Preparation Products
AT-130 (AT130) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2996 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shandong WorldSun Biological Technology Co., Ltd. | 0531-88723173 18596073690 | 1047208234@qq.com | China | 8174 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| Zhengzhou convergence chemical co., LTD | 037155153829 18003835034 | 3897192574@qq.com | China | 9982 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | +86-0513; 18051384581 | sales@chemhifuture.com | China | 3075 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Shanghai Guangyang Carrie Biotechnology Co., LTD | 13127532723 | lily@yhp-biomedicine.com | China | 800 | 58 |
