2-Amino-5-chloro-2',6'-difluorobenzophenone
- CAS No.
- 28910-83-0
- Chemical Name:
- 2-Amino-5-chloro-2',6'-difluorobenzophenone
- Synonyms
- 4-chloro-2-(2,6-difluorobenzoyl)aniline;2-Amino-5-chloro-2',6'-difluorobenzophenone;2-Amino-5-chloro-2',6'-difluorobenzophenone 98%;2-Amino-5-chloro-2',6'-difluorobenzophenone 98+%;2-AMINO-5-CHLORO-PHENYL-(2-6-DIFLUORO-PHENYL)-METHANONE;Methanone, (2-amino-5-chlorophenyl)(2,6-difluorophenyl)-;6-benzoyl-4-chloro-1,5-difluorocyclohexa-2,4-dien-1-aMine;2-Amino-5-chloro-2′,6′-difluoro-benzophenone, CAS 28910-83-0
- CBNumber:
- CB9489864
- Molecular Formula:
- C13H8ClF2NO
- Molecular Weight:
- 267.66
- MDL Number:
- MFCD06659048
- MOL File:
- 28910-83-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 151-153°C |
|---|---|
| Boiling point | 435.2±45.0 °C(Predicted) |
| Density | 1.407±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -1.71±0.10(Predicted) |
| color | Yellow |
| InChI | InChI=1S/C13H8ClF2NO/c14-7-4-5-11(17)8(6-7)13(18)12-9(15)2-1-3-10(12)16/h1-6H,17H2 |
| InChIKey | DUMGVPIXKALANS-UHFFFAOYSA-N |
| SMILES | C(C1=CC(Cl)=CC=C1N)(C1=C(F)C=CC=C1F)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2922390090 |
2-Amino-5-chloro-2',6'-difluorobenzophenone price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC6424 | 2-Amino-5-chloro-2',6'-difluorobenzophenone >98% | 28910-83-0 | 1g | $22 | 2026-06-04 | Buy |
| Apolloscientific | PC6424 | 2-Amino-5-chloro-2',6'-difluorobenzophenone >98% | 28910-83-0 | 5g | $74 | 2026-06-04 | Buy |
| Apolloscientific | PC6424 | 2-Amino-5-chloro-2',6'-difluorobenzophenone >98% | 28910-83-0 | 25g | $293 | 2026-06-04 | Buy |
| Apolloscientific | PC6424 | 2-Amino-5-chloro-2',6'-difluorobenzophenone >98% | 28910-83-0 | 100g | $773 | 2026-06-04 | Buy |
| Matrix Scientific | 090374 | (2-Amino-5-chlorophenyl)-(2,6-difluorophenyl)methanone | 28910-83-0 | 1.00g | $88 | 2026-05-18 | Buy |
2-Amino-5-chloro-2',6'-difluorobenzophenone Chemical Properties, Uses, Production
Chemical Properties
Yellow Solid
Uses
2-Aminobenzophenone derivative.
Synthesis
869365-92-4
28910-83-0
The general procedure for the synthesis of 2-amino-5-chloro-2,6-difluorobenzophenone using [4-chloro-2-(2,6-difluorobenzyl)phenyl]-carbamic acid-1,1-dimethylethyl ester as a starting material was as follows: the N-Boc-protected aminobenzophenone was dissolved in anhydrous dichloromethane (50 mL), followed by the addition of trifluoroacetic acid (50 mL). The reaction mixture was stirred for 1 h at room temperature and then the solvent was evaporated to dryness by rotary evaporator under vacuum. The resulting residue was dissolved in a mixture of ethyl acetate (100 mL) and saturated aqueous sodium bicarbonate (100 mL). The organic phase was separated and washed with saturated aqueous sodium bicarbonate solution and subsequently dried with anhydrous magnesium sulfate. The dried organic phase was concentrated to dryness by rotary evaporator and the target product 2-amino-5-chloro-2,6-difluorobenzophenone was quantitatively obtained, and mass spectrometry analysis showed m/z = 268 (M + H).
References
[1] Patent: US2005/256102, 2005, A1. Location in patent: Page/Page column 140
[2] Angewandte Chemie - International Edition, 2012, vol. 51, # 27, p. 6598 - 6603
2-Amino-5-chloro-2',6'-difluorobenzophenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Z IntellecChem& Tech. Co., Ltd | 0511-15050866711; 15050866711 | contact@zintellec.com | China | 93 | 62 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Lavem Chine Pharm Company | 028-62070218 18190869852 | sales@lavemc.com | China | 214 | 67 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 |
View Latest Price from 2-Amino-5-chloro-2',6'-difluorobenzophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
28910-83-0
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-07-06 | 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
28910-83-0
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
28910-83-0
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
28910-83-0
- $1.00
- 99%
- Career Henan Chemical Co
