Protoporphyrin IX dimethyl ester
- CAS No.
- 5522-66-7
- Chemical Name:
- Protoporphyrin IX dimethyl ester
- Synonyms
- Protoporphyrin dimethyl;dimethyl protoporphyrin IX;Protoporphyrin IX diMethyl es;Protoporphyrin IX dimethyl ester;Dimethylprotoporphyrin IX dimethyl ester;Protoporphyrin IX dimethyl ester, ≥95%(HPLC);Protoporphyrin IX dimethyl ester ~90% (HPLC);PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN;dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate;dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
- CBNumber:
- CB9497515
- Molecular Formula:
- C36H38N4O4
- Molecular Weight:
- 590.71
- MDL Number:
- MFCD29047709
- MOL File:
- 5522-66-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 225-228 °C(lit.) |
|---|---|
| Boiling point | 1017.0±65.0 °C(Predicted) |
| Density | 1.220±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO: soluble |
| form | crystal |
| color | purple |
| BRN | 381574 |
| Stability | Light Sensitive |
| InChIKey | WASRLAPXOHTNAX-MFBGAUBSSA-N |
| SMILES | C(C1=C(C2=CC3=NC(=CC4=C(C=C)C(C)=C(N4)C=C4C(C)=C(CCC(=O)OC)C(=N4)C=C1N2)C(C)=C3C=C)C)CC(=O)OC |c:7,t:3,18,32| |
| FDA UNII | PHV7RHT9L3 |
| EPA Substance Registry System | 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, dimethyl ester (5522-66-7) |
| UNSPSC Code | 12171500 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H303-H320 |
| Precautionary statements | P312-P264-P305+P351+P338-P337+P313 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| F | 8-10-23 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
Protoporphyrin IX dimethyl ester price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 09626 | Protoporphyrin IX dimethyl ester ~90% (HPLC) | 5522-66-7 | 100mg | $212 | 2026-04-30 | Buy |
| TCI Chemical | D6148 | Protoporphyrin IX Dimethyl Ester | 5522-66-7 | 100MG | $131 | 2026-04-30 | Buy |
| Strem Chemicals | 07-1850 | Protoporphyrin IX, dimethyl ester | 5522-66-7 | 100mg | $133 | 2026-04-30 | Buy |
| Strem Chemicals | 07-1850 | Protoporphyrin IX, dimethyl ester | 5522-66-7 | 500mg | $469 | 2026-04-30 | Buy |
| Biosynth | W-105577 | Protoporphyrin IX dimethyl ester | 5522-66-7 | 1kg | $41250 | 2026-06-05 | Buy |
Protoporphyrin IX dimethyl ester Chemical Properties, Uses, Production
Chemical Properties
Protoporphyrin IX dimethyl ester is a dark purple powder. Solubility: soluble in DMSO, acetone, and chloroform.
Uses
Protoporphyrin IX Dimethyl Ester is a derivative of Protoporphyrin IX (P839138), which is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls.
Definition
ChEBI: Dimethylprotoporphyrin IX dimethyl ester is a member of porphyrins.
Purification Methods
The crude dimethyl ester (1g) in CHCl3 (200 mL) is mixed with pet ether (b 70-90o, 600mL), and any porphyrin (m > 260o) which is insoluble in this mixture is filtered off. The filtrate is passed through a column of CaCO3 [from CaCO3 (130g) which is kept overnight in a mixture of CHCl3/pet ether (b 70-90o, 1:3), and the slurry is poured into a glass tube (2.5 x 26cm) to form the column]. After all the filtrate is applied, the column is eluted with a solution of CHCl3/pet ether (b 70-90o, 1:3). All the coloured eluates are collected, evaporated at room temperature in a vacuum to give a residue (0.8g), m 208-211o. The residue (0.8g) in CHCl3 (66mL) is heated briefly to its boiling point, then boiling MeOH (198mL) is added immediately to it. The mixture is allowed to cool to room temperature, refrigerated for 2days and the solid is filtered off. The solid is washed on the filter funnel with CHCl3/MeOH (1:9, 50mL) and dried at 50o/vacuum (yield 0.62-0.66g). It can also be recrystallised by dissolving in as little hot dry *C6H6 as possible and left overnight at 20o, m 228-230o. It has also been purified by dissolving (0.4g) in CHCl3 (33mL) by boiling for a few minutes, then diluting with boiling MeOH (100mL) and refrigerating for 2days. The crystals are collected, washed with CHCl3/MeOH (1:9) and dried at 50o in a vacuum (yield 0.3g). The UV has max at 631, 576, 541, 506 and 407nm in CHCl3 and 601, 556 and 406nm in 25% HCl. [Ramsey Biochemical Preparations 3 39 1953, Beilstein 26 III/IV 3052.]
Protoporphyrin IX dimethyl ester Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xianhui Pharmaceutical Co., Ltd. | 13564796979; 13564796979 | shxh2006@outlook.com | China | 32 | 62 |
| Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 | 2306208234@qq.com | China | 1006 | 50 |
| Hangzhou FuRun Pharmaceutical Technology Co., Ltd | 15658004993 | 1900830611@qq.com | China | 980 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +86-15658003402 | sales@newcanbio.com | China | 1984 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
View Latest Price from Protoporphyrin IX dimethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | Protoporphyrin IX dimethyl ester
5522-66-7
|
1KG | 95.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2026-05-28 | Protoporphyrin IX dimethyl ester
5522-66-7
|
$1.90 | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2026-03-20 | Protoporphyrin IX dimethyl ester
5522-66-7
|
$10.00 | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- Protoporphyrin IX dimethyl ester
5522-66-7
- 95.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- Protoporphyrin IX dimethyl ester
5522-66-7
- $1.90
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- Protoporphyrin IX dimethyl ester
5522-66-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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