ChemicalBook >> CAS DataBase List >>Protoporphyrin IX dimethyl ester

Protoporphyrin IX dimethyl ester

CAS No.
5522-66-7
Chemical Name:
Protoporphyrin IX dimethyl ester
Synonyms
Protoporphyrin dimethyl;dimethyl protoporphyrin IX;Protoporphyrin IX diMethyl es;Protoporphyrin IX dimethyl ester;Dimethylprotoporphyrin IX dimethyl ester;Protoporphyrin IX dimethyl ester, ≥95%(HPLC);Protoporphyrin IX dimethyl ester ~90% (HPLC);PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN;dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate;dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
CBNumber:
CB9497515
Molecular Formula:
C36H38N4O4
Molecular Weight:
590.71
MDL Number:
MFCD29047709
MOL File:
5522-66-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:12:03

Protoporphyrin IX dimethyl ester Properties

Melting point 225-228 °C(lit.)
Boiling point 1017.0±65.0 °C(Predicted)
Density 1.220±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO: soluble
form crystal
color purple
BRN 381574
Stability Light Sensitive
InChIKey WASRLAPXOHTNAX-MFBGAUBSSA-N
SMILES C(C1=C(C2=CC3=NC(=CC4=C(C=C)C(C)=C(N4)C=C4C(C)=C(CCC(=O)OC)C(=N4)C=C1N2)C(C)=C3C=C)C)CC(=O)OC |c:7,t:3,18,32|
FDA UNII PHV7RHT9L3
EPA Substance Registry System 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, dimethyl ester (5522-66-7)
UNSPSC Code 12171500
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H320
Precautionary statements  P312-P264-P305+P351+P338-P337+P313
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
8-10-23
TSCA  TSCA listed
Storage Class 11 - Combustible Solids

Protoporphyrin IX dimethyl ester price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 09626 Protoporphyrin IX dimethyl ester ~90% (HPLC) 5522-66-7 100mg $212 2026-04-30 Buy
TCI Chemical D6148 Protoporphyrin IX Dimethyl Ester 5522-66-7 100MG $131 2026-04-30 Buy
Strem Chemicals 07-1850 Protoporphyrin IX, dimethyl ester 5522-66-7 100mg $133 2026-04-30 Buy
Strem Chemicals 07-1850 Protoporphyrin IX, dimethyl ester 5522-66-7 500mg $469 2026-04-30 Buy
Biosynth W-105577 Protoporphyrin IX dimethyl ester 5522-66-7 1kg $41250 2026-06-05 Buy
Product number Packaging Price Buy
09626 100mg $212 Buy
D6148 100MG $131 Buy
07-1850 100mg $133 Buy
07-1850 500mg $469 Buy
W-105577 1kg $41250 Buy

Protoporphyrin IX dimethyl ester Chemical Properties, Uses, Production

Chemical Properties

Protoporphyrin IX dimethyl ester is a dark purple powder. Solubility: soluble in DMSO, acetone, and chloroform.

Uses

Protoporphyrin IX Dimethyl Ester is a derivative of Protoporphyrin IX (P839138), which is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls.

Definition

ChEBI: Dimethylprotoporphyrin IX dimethyl ester is a member of porphyrins.

Purification Methods

The crude dimethyl ester (1g) in CHCl3 (200 mL) is mixed with pet ether (b 70-90o, 600mL), and any porphyrin (m > 260o) which is insoluble in this mixture is filtered off. The filtrate is passed through a column of CaCO3 [from CaCO3 (130g) which is kept overnight in a mixture of CHCl3/pet ether (b 70-90o, 1:3), and the slurry is poured into a glass tube (2.5 x 26cm) to form the column]. After all the filtrate is applied, the column is eluted with a solution of CHCl3/pet ether (b 70-90o, 1:3). All the coloured eluates are collected, evaporated at room temperature in a vacuum to give a residue (0.8g), m 208-211o. The residue (0.8g) in CHCl3 (66mL) is heated briefly to its boiling point, then boiling MeOH (198mL) is added immediately to it. The mixture is allowed to cool to room temperature, refrigerated for 2days and the solid is filtered off. The solid is washed on the filter funnel with CHCl3/MeOH (1:9, 50mL) and dried at 50o/vacuum (yield 0.62-0.66g). It can also be recrystallised by dissolving in as little hot dry *C6H6 as possible and left overnight at 20o, m 228-230o. It has also been purified by dissolving (0.4g) in CHCl3 (33mL) by boiling for a few minutes, then diluting with boiling MeOH (100mL) and refrigerating for 2days. The crystals are collected, washed with CHCl3/MeOH (1:9) and dried at 50o in a vacuum (yield 0.3g). The UV has max at 631, 576, 541, 506 and 407nm in CHCl3 and 601, 556 and 406nm in 25% HCl. [Ramsey Biochemical Preparations 3 39 1953, Beilstein 26 III/IV 3052.]

553-12-8
5522-66-7
Synthesis of Protoporphyrin IX dimethyl ester from Protoporphyrin IX
Global Suppliers ( 132)
Supplier Tel Email Country ProdList Advantage
Shanghai Xianhui Pharmaceutical Co., Ltd. 13564796979; 13564796979 shxh2006@outlook.com China 32 62
Chengdu Aslee Biopharmaceuticals, Inc 028-85305008 02885305008 2306208234@qq.com China 1006 50
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 15658004993 1900830611@qq.com China 980 58
NewCan Biotech Limited +86-0571-86912261 +86-15658003402 sales@newcanbio.com China 1984 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58

View Latest Price from Protoporphyrin IX dimethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Protoporphyrin IX dimethyl ester pictures 2026-06-30 Protoporphyrin IX dimethyl ester
5522-66-7
1KG 95.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Protoporphyrin IX dimethyl ester pictures 2026-05-28 Protoporphyrin IX dimethyl ester
5522-66-7
$1.90 1KG 99% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
Protoporphyrin IX dimethyl ester pictures 2026-03-20 Protoporphyrin IX dimethyl ester
5522-66-7
$10.00 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
Protoporphyrin IX dimethyl ester, ≥95%(HPLC) methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxo-propyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxopropyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate Protoporphyrin IX diMethyl es 21H,23H-Porphine-2,18-dipropanoicacid, 7,12-diethenyl-3,8,13,17-tetraMethyl-, 2,18-diMethyl ester ProtoporphyrinIX dimethyl ester,Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate, Ooporpyhrin dimethyl ester dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-Porphine-2,18-dipropanoic acid- 2,18-dimethyl ester Dimethylprotoporphyrin IX dimethyl ester dimethyl protoporphyrin IX Ooporpyhrin dimethyl ester, Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate 3,8,13,17-Tetramethyl-7,12-diethenyl-21H,23H-porphyrin-2,18-dipropionic acid dimethyl ester 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphyrin-2,18-bis(propionic acid methyl) ester Protoporphyrin dimethyl 3-[18-(3-keto-3-methoxy-propyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphin-2-yl]propionic acid methyl ester dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN Protoporphyrin IX dimethyl ester Protoporphyrin IX dimethyl ester ~90% (HPLC) Dimethyl 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate 2,18-Dimethyl 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoate 5522-66-7 porphine (porphyrin) ligand