Secalonic acid D from penicillium*oxalicum
- CAS No.
- 35287-69-5
- Chemical Name:
- Secalonic acid D from penicillium*oxalicum
- Synonyms
- sad;secalonicacidd;lpha,4-beta,4a-beta,7(3’r,4’s,4’as)));Secalonic acid D from penicillium*oxalicum;ergochromeaa(2,2’)-5-beta,6-alpha,10-beta-5’,6’-alpha,10’-beta;7’-bi-4ah-xanthene)-4a,4’a-dicarboxylicacid,2,2’,3,3’,4,4’,9,9’-octahydro-(;1,1’,4,4’,8,8’-hexahydroxy-3,3’-dimethyl-9,9’-dioxo-,dimethylester,(3s-(3-a;[7,7'-Bi-4aH-xanthene]-4a,4'a-dicarboxylic acid, 2,2',3,3',4,4',9,9'-octahydro-1,1',4,4',8,8'-hexahydroxy-3,3'-dimethyl-9,9'-dioxo-, 4a,4'a-dimethyl ester, (3S,3'S,4R,4'R,4aR,4'aR)-
- CBNumber:
- CB9504561
- Molecular Formula:
- C32H30O14
- Molecular Weight:
- 638.57
- MDL Number:
- MFCD32205821
- MOL File:
- 35287-69-5.mol
- TDS File:
- TDS
| Melting point | 257°C |
|---|---|
| Boiling point | 591.32°C (rough estimate) |
| Density | 1.3167 (rough estimate) |
| refractive index | 1.6130 (estimate) |
| storage temp. | 2-8°C |
| pka | 4.199±1.00(predicted) |
| FDA UNII | HZP8L3M5ME |
SAFETY
Risk and Safety Statements
| Hazard Codes | T+ |
|---|---|
| Risk Statements | 28 |
| Safety Statements | 28-36/37-45 |
| RIDADR | UN 2811 6.1/PG 2 |
| RTECS | EC2460000 |
Secalonic acid D from penicillium*oxalicum price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0650234 | Secalonic acid D 99.63% | 35287-69-5 | 1mg | $563 | 2026-06-04 | Buy |
| ChemScene | CS-0650234 | Secalonic acid D 99.63% | 35287-69-5 | 5mg | $1417 | 2026-06-04 | Buy |
| Arctom | HY-N11576 | Secalonic acid D 99.63% | 35287-69-5 | 1mg | $654 | 2026-05-26 | Buy |
| Arctom | HY-N11576 | Secalonic acid D 99.63% | 35287-69-5 | 5mg | $1645 | 2026-05-26 | Buy |
| American Custom Chemicals Corporation | TOX0000049 | SECALONIC ACID D 95.00% | 35287-69-5 | 5MG | $502.38 | 2021-12-16 | Buy |
Secalonic acid D from penicillium*oxalicum Chemical Properties, Uses, Production
Uses
Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-β, and degrades β-catenin. Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis[1][2].
Definition
ChEBI: Secalonic acid D is a member of xanthenes.
References
[1] Andersen R, et al. Secalonic acids D and F are toxic metabolites of Aspergillus aculeatus. J Org Chem. 1977 Jan 21;42(2):352-3. DOI:10.1021/jo00422a042
[2] Zhang JY, et al. Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway. Cell Cycle. 2009 Aug;8(15):2444-50. DOI:10.4161/cc.8.15.9170
Secalonic acid D from penicillium*oxalicum Preparation Products And Raw materials
Raw materials
Preparation Products
Secalonic acid D from penicillium*oxalicum Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Asperillum Ltm | 15920419256 | huangxishan13@foxmail.com | China | 177 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Nantong Gruechem Pharmaceutical Co., Ltd. | 13809088763 | sales@gruechem.com | China | 30 | 58 |
| Changzhou Xianglong Pharmaceutical Technology Co., LTD | 18661161657 | sales@xianglongpharm.com | China | 10000 | 58 |
| Hubei Bolan Chemical Co., LTD | 13297969979 13297969979 | nxiaoshida2@163.com | China | 711 | 58 |
