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AC-YVAD-PNA

AC-YVAD-PNA structure

CAS No.: 149231-66-3

Chemical Name:: AC-YVAD-PNA

Synonyms: AC-YVAD-PNA;ACETYL-YVAD-PNA;ICE SUBSTRATE IV;AC-TYR-VAL-ALA-ASP-PNA;Caspase-1 Substrate IV;REF DUPL: Ac-Tyr-Val-Ala-Asp-pNA;CASPASE-1 SUBSTRATE (CHROMOGENIC);AC-TYR-VAL-ALA-ASP-PNA: AC-YVAD-PNA;AC-TYR-VAL-ALA-ASP-PARANITROANILIDE;IL-1B CONVERTING ENZYME SUBSTRATE IV

CBNumber:: CB9669912

Molecular Formula:: C29H36N6O10

Molecular Weight:: 628.63

MDL Number:: MFCD00274387

MOL File:: 149231-66-3.mol

MSDS File:: SDS

Last updated:2025-06-18 16:39:22

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AC-YVAD-PNA Properties

Boiling point	1108.9±65.0 °C(Predicted)
Density	1.362±0.06 g/cm3(Predicted)
storage temp.	-15°C
form	powder
pka	4.04±0.10(Predicted)
color	white to beige
Sequence	Ac-Tyr-Val-Ala-Asp-{pNA}
UNSPSC Code	12352200
NACRES	NA.77

AC-YVAD-PNA price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1424	Ac-YVAD-pNA ≥98% (HPLC)	149231-66-3	5mg	$103	2025-07-31	Buy
Sigma-Aldrich	SML1424	Ac-YVAD-pNA ≥98% (HPLC)	149231-66-3	25mg	$414	2025-07-31	Buy
Cayman Chemical	17487	Ac-YVAD-pNA ≥95%	149231-66-3	5mg	$69	2021-12-16	Buy
Cayman Chemical	17487	Ac-YVAD-pNA ≥95%	149231-66-3	1mg	$25	2021-12-16	Buy
Cayman Chemical	17487	Ac-YVAD-pNA ≥95%	149231-66-3	10mg	$125	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML1424	5mg	$103	Buy
SML1424	25mg	$414	Buy
17487	5mg	$69	Buy
17487	1mg	$25	Buy
17487	10mg	$125	Buy

AC-YVAD-PNA Chemical Properties,Uses,Production

Uses

N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.

Biological Activity

Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.

IC 50

Caspase-1

AC-YVAD-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

AC-YVAD-PNA Suppliers

Global( 120)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	995	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
Moxin Chemicals	+8617320513646	Anna@molcoo.com	China	9902	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Cellmano Biotech Limited	58
Hangzhou Go Top Peptide Biotech	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Aladdin Scientific	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
Moxin Chemicals	58
GL Biochem (Shanghai) Ltd	64
VDM Biochemicals	64

149231-66-3(AC-YVAD-PNA)Related Search:

AC-VDVAD-PNA Z-VAD-FMK CASPASE INHIBITOR3 AC-VEID-AMC Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE

Z-YVAD-AFC ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL AC-VDVAD-CHO AC-DEVD-AFC PAC1

AC-DEVD-CHO AC-LEHD-AFC AC-LEU-GLU-THR-ASP-AFC 4-(4-AMINOANILINO)-4-OXOBUTANOIC ACID SUC-TYR-VAL-ALA-ASP-PNA

AC-ASP-PNA AC-YVAD-PNA AC-YVAD-CHO

1of4

AC-TYR-VAL-ALA-ASP-PNA N-ACETYL-TYR-VAL-ALA-ASP-P-NITROANILIDE PNA N-acetyl-tyr-val-ala-asp P-nitroanilide AC-TYR-VAL-ALA-ASP-PNA: AC-YVAD-PNA REF DUPL: Ac-Tyr-Val-Ala-Asp-pNA CASPASE-1 SUBSTRATE IV, COLORIMETRIC CASPASE-1 SUBSTRATE (CHROMOGENIC) CASPASE 1 (ICE) SUBSTRATE 2, CHROMOGENIC ICE SUBSTRATE IV IL-1B CONVERTING ENZYME SUBSTRATE IV IL-1BETA CONVERTING ENZYME (ICE) COLORIMETRIC SUBSTRATE ACETYL-TYR-VAL-ALA-ASP-(P-NITROANILIDE) ACETYL-YVAD-PNA AC-YVAD-PNA N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-a-asparagine AC-TYR-VAL-ALA-ASP-PARANITROANILIDE Caspase-1 Substrate IV L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)- Caspase 1 (ICE) Substrate 2, chromogenic - 5 mg 149231-66-3 C29H36N6O10 Caspase/Related Products Pepetides Peptide