ChemicalBook >> CAS DataBase List >>AC-YVAD-PNA
AC-YVAD-PNA
- CAS No.
- 149231-66-3
- Chemical Name:
- AC-YVAD-PNA
- Synonyms
- AC-YVAD-PNA;ACETYL-YVAD-PNA;ICE SUBSTRATE IV;AC-TYR-VAL-ALA-ASP-PNA;Caspase-1 Substrate IV;REF DUPL: Ac-Tyr-Val-Ala-Asp-pNA;CASPASE-1 SUBSTRATE (CHROMOGENIC);AC-TYR-VAL-ALA-ASP-PNA: AC-YVAD-PNA;AC-TYR-VAL-ALA-ASP-PARANITROANILIDE;IL-1B CONVERTING ENZYME SUBSTRATE IV
- CBNumber:
- CB9669912
- Molecular Formula:
- C29H36N6O10
- Molecular Weight:
- 628.63
- MDL Number:
- MFCD00274387
- MOL File:
- 149231-66-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:22
| Product description | Number | Pack Size | Price |
| Ac-YVAD-pNA ≥98% (HPLC) | SML1424 | 5mg | $111 |
| Ac-YVAD-pNA ≥98% (HPLC) | SML1424 | 25mg | $444 |
| Ac-YVAD-pNA ≥95% | 17487 | 1mg | $25 |
| Ac-YVAD-pNA ≥95% | 17487 | 5mg | $69 |
| Ac-YVAD-pNA | J-008571 | 10mg | $194.7 |
| Boiling point | 1108.9±65.0 °C(Predicted) |
|---|---|
| Density | 1.362±0.06 g/cm3(Predicted) |
| storage temp. | -15°C |
| pka | 4.04±0.10(Predicted) |
| form | powder |
| color | white to beige |
| Sequence | Ac-Tyr-Val-Ala-Asp-{pNA} |
| InChIKey | YDPNOCSPPGFBPX-XNHCRPTKSA-N |
| SMILES | O=C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC1=CC=C(O)C=C1)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
AC-YVAD-PNA price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1424 | Ac-YVAD-pNA ≥98% (HPLC) | 149231-66-3 | 5mg | $111 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1424 | Ac-YVAD-pNA ≥98% (HPLC) | 149231-66-3 | 25mg | $444 | 2026-04-30 | Buy |
| Cayman Chemical | 17487 | Ac-YVAD-pNA ≥95% | 149231-66-3 | 1mg | $25 | 2021-12-16 | Buy |
| Cayman Chemical | 17487 | Ac-YVAD-pNA ≥95% | 149231-66-3 | 5mg | $69 | 2021-12-16 | Buy |
| Biosynth | J-008571 | Ac-YVAD-pNA | 149231-66-3 | 10mg | $194.7 | 2026-06-04 | Buy |
AC-YVAD-PNA Chemical Properties,Uses,Production
Uses
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.
Biological Activity
Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.
IC 50
Caspase-1
AC-YVAD-PNA Preparation Products And Raw materials
Raw materials
Preparation Products
AC-YVAD-PNA Suppliers
Global( 120)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| ANHUI BYERSEN BIOTECH CO. LTD | +86-15385096007 +86-17755058861 | amy@byersenchemical.com | China | 10000 | 58 |
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | 15051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1010 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29988 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
149231-66-3(AC-YVAD-PNA)Related Search:
AC-TYR-VAL-ALA-ASP-PNA
N-ACETYL-TYR-VAL-ALA-ASP-P-NITROANILIDE PNA
N-acetyl-tyr-val-ala-asp P-nitroanilide
AC-TYR-VAL-ALA-ASP-PNA: AC-YVAD-PNA
REF DUPL: Ac-Tyr-Val-Ala-Asp-pNA
CASPASE-1 SUBSTRATE IV, COLORIMETRIC
CASPASE-1 SUBSTRATE (CHROMOGENIC)
CASPASE 1 (ICE) SUBSTRATE 2, CHROMOGENIC
ICE SUBSTRATE IV
IL-1B CONVERTING ENZYME SUBSTRATE IV
IL-1BETA CONVERTING ENZYME (ICE) COLORIMETRIC SUBSTRATE
ACETYL-TYR-VAL-ALA-ASP-(P-NITROANILIDE)
ACETYL-YVAD-PNA
AC-YVAD-PNA
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-a-asparagine
AC-TYR-VAL-ALA-ASP-PARANITROANILIDE
Caspase-1 Substrate IV
L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-
Caspase 1 (ICE) Substrate 2, chromogenic - 5 mg
149231-66-3
C29H36N6O10
Caspase/Related Products
Pepetides
Peptide
