ChemicalBook >> CAS DataBase List >>4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER structure

CAS No.: 27568-04-3

Chemical Name:: 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Synonyms: NSC 196905;BUTTPARK 20\09-65;ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE;ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE;ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate;2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate;Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate;4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester;4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

CBNumber:: CB9673423

Molecular Formula:: C13H13NO4

Molecular Weight:: 247.25

MDL Number:: MFCD00173382

MOL File:: 27568-04-3.mol

MSDS File:: SDS

Last updated:2026-05-28 05:39:11

Product description	Number	Pack Size	Price
4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester Aldrich	BBO000182	1g	$62.4
Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	OR59342	5g	$21
Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	OR59342	25g	$70
Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	OR59342	100g	$275
Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	OR59342	500g	$1231

Request For Quotation

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Properties

Boiling point	373.2±37.0 °C(Predicted)
Density	1.277
storage temp.	Sealed in dry,Room Temperature
form	solid
pka	2.72±0.50(Predicted)
Appearance	Light yellow to brown Solid
InChI	1S/C13H13NO4/c1-3-18-13(16)9-7-14-11-8(12(9)15)5-4-6-10(11)17-2/h4-7H,3H2,1-2H3,(H,14,15)
InChIKey	HCYNWEIHLHVPEW-UHFFFAOYSA-N
SMILES	CCOC(=O)c1cnc2c(OC)cccc2c1O
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305+P351+P338
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26-24/25
WGK Germany	3
HS Code	29334900
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	BBO000182	4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester Aldrich	27568-04-3	1g	$62.4	2026-04-30	Buy
Apolloscientific	OR59342	Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	27568-04-3	5g	$21	2026-06-04	Buy
Apolloscientific	OR59342	Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	27568-04-3	25g	$70	2026-06-04	Buy
Apolloscientific	OR59342	Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	27568-04-3	100g	$275	2026-06-04	Buy
Apolloscientific	OR59342	Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate >95%	27568-04-3	500g	$1231	2026-06-04	Buy

Product number	Packaging	Price	Buy
BBO000182	1g	$62.4	Buy
OR59342	5g	$21	Buy
OR59342	25g	$70	Buy
OR59342	100g	$275	Buy
OR59342	500g	$1231	Buy

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Chemical Properties

Off-white solid

Synthesis

2-ANISIDONEMETHYLENEMALONIC ACID DIETHYL ESTER

104007-09-2

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

27568-04-3

Step B: Synthesis of ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate: Diethyl 2-(((2-methoxyphenyl)amino)methylene)malonate (47.6 g, 162 mmol) was suspended in Dowtherm (100 mL) and heated to 250 °C. The reaction mixture was kept in a sand bath overnight, subsequently cooled to room temperature and diluted with pentane (750 mL). The resulting solid product was collected by filtration and washed with hexane to afford the target compound (25.7 g, 64% yield). Mass spectrometry analysis (APCI) showed m/z 248.0 ([M + H]+).

References

[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 66

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER synthesis

Synthesis of 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER from 2-ANISIDONEMETHYLENEMALONIC ACID DIETHYL ESTER

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

o-Anisidine Diethyl ethoxymethylenemalonate Diphenyl ether Petroleum ether 2-ANISIDONEMETHYLENEMALONIC ACID DIETHYL ESTER

Preparation Products

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20584	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9539	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Suzhou Victorypharm Co.,Ltd.	+86-13916956214	sales@victory-pharm.com	China	1299	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49967	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	5994	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

Supplier	Advantage
career henan chemical co	58
Wuhan Chemwish Technology Co., Ltd	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Suzhou Victorypharm Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
Nanjing Bicbiotechnology Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
Amadis Chemical Company Limited	58

View Lastest Price from 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 27568-04-3	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2019-07-06	4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 27568-04-3	$3.00	1KG	90%-99.9%	1000kg	Career Henan Chemical Co

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
27568-04-3
$1.10
99.00%
Dideu Industries Group Limited

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
27568-04-3
$3.00
90%-99.9%
Career Henan Chemical Co

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Spectrum

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER(27568-04-3)¹HNMR

27568-04-3(4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER)Related Search:

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate 7-BROMO-1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-6-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester

4-HYDROXY-8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLIC ACID 8-METHOXYQUINOLINE 4-HYDROXY-8-METHOXY-QUINOLINE-2-CARBOXYLIC ACID ETHYL ESTER ETHYL 4-HYDROXY-8-(TRIFLUOROMETHOXY)QUINOLINE-3-CARBOXYLATE

Moxifloxacin Acyl-b-D-glucuronide 1-CYCLOPROPYL-7-FLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-3-QUINOLINECARBOXYLIC ACID, ETHYL ESTER ETHYL 8-METHOXY-4-(2-NAPHTHYLOXY)-3-QUINOLINECARBOXYLATE ETHYL 8-METHOXY-4-PHENOXY-3-QUINOLINECARBOXYLATE ETHYL 4-(4-FLUOROPHENOXY)-8-METHOXY-3-QUINOLINECARBOXYLATE

BUTTPARK 42\01-38 ETHYL 4-HYDROXY-8-METHOXY-6-NITROQUINOLINE-3-CARBOXYLATE 4-HYDROXY-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ETHYL ESTER

1of4

4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ETHYL 4-HYDROXY-8-METHOXY-3-QUINOLINECARBOXYLATE ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE BUTTPARK 20\09-65 2-ethyl-8-methoxy-4-oxo-1H-quinoline-3-carboxylate Ethyl 1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylate Ethyl 8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate 4-keto-8-methoxy-1H-quinoline-3-carboxylic acid ethyl ester ethyl 8-methoxy-4-oxo-1H-quinoline-3-carboxylate 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester ,95% NSC 196905 3-Quinolinecarboxylic acid, 4-hydroxy-8-methoxy-, ethyl ester 4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH 27568-04-3 blocks Carboxes Quinolines pharmacetical