4-Methylaniline hydrochloride
- CAS No.
- 540-23-8
- Chemical Name:
- 4-Methylaniline hydrochloride
- Synonyms
- P-TOLUIDINE HYDROCHLORIDE;P-TOLUIDINE HCL;4-methylaniline HCL;Toluidinium chloride;P-TOLUIDINIUM CHLORIDE;p-Toluidine hydrochlori;ρ-Toluidine hydrochliride;4-methylaniliniumchloride;4-TOLUIDINE HYDROCHLORIDE;p-methylaniliniumchloride
- CBNumber:
- CB9689488
- Molecular Formula:
- C7H10ClN
- Molecular Weight:
- 143.61
- MDL Number:
- MFCD00035497
- MOL File:
- 540-23-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 243-245 °C(lit.) |
|---|---|
| Density | 1.193 g/cm3 |
| storage temp. | Store below +30°C. |
| Water Solubility | Soluble in water |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | powder to crystal |
| color | White to Gray to Red |
| BRN | 3557540 |
| Stability | Hygroscopic |
| InChI | 1S/C7H9N.ClH/c1-6-2-4-7(8)5-3-6;/h2-5H,8H2,1H3;1H |
| InChIKey | JQKBUTDZZRGQDR-UHFFFAOYSA-N |
| SMILES | Cl[H].Cc1ccc(N)cc1 |
| CAS DataBase Reference | 540-23-8(CAS DataBase Reference) |
| FDA UNII | PT5II901IF |
| EPA Substance Registry System | p-Toluidine hydrochloride (540-23-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H319-H317-H351-H400 | |||||||||
| Precautionary statements | P501-P261-P273-P272-P270-P202-P201-P271-P264-P280-P391-P308+P313-P337+P313-P305+P351+P338-P361+P364-P333+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 23/24/25-36-40-43-50 | |||||||||
| Safety Statements | 28-36/37-45-61 | |||||||||
| RIDADR | UN 2811 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XU7525000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29214300 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 Carc. 2 Eye Irrit. 2 Skin Sens. 1 |
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| NFPA 704 |
|
4-Methylaniline hydrochloride price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 89650 | p-Toluidine hydrochloride purum, ≥99.0% (AT) | 540-23-8 | 100g | $104 | 2026-04-30 | Buy |
| Sigma-Aldrich | 89650 | p-Toluidine hydrochloride purum, ≥99.0% (AT) | 540-23-8 | 500g | $476 | 2026-04-30 | Buy |
| TCI Chemical | T0303 | p-Toluidine Hydrochloride >98.0%(HPLC)(N) | 540-23-8 | 25g | $23 | 2026-04-30 | Buy |
| TCI Chemical | T0303 | p-Toluidine Hydrochloride >98.0%(HPLC)(N) | 540-23-8 | 500g | $152 | 2026-04-30 | Buy |
| TRC | TRC-T536240-5G | p-Toluidine Hydrochloride | 540-23-8 | 5g | $68 | 2026-06-03 | Buy |
4-Methylaniline hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white to light beige crystalline powder, crystals
Uses
p-Toluidine Hydrochloride acts as a reagent for the preparation and biological activity of N-acylleucine (arylaminoethyl)amides as non-covalent inhibitors of cathepsin K, L and S. Catalyst in the chemistry of azasteroids.
General Description
Off-white to grayish-white crystals.
Air & Water Reactions
Water soluble. May be sensitive to moisture.
Reactivity Profile
4-Methylaniline hydrochloride reacts with oxidizing and alkali materials. .
Fire Hazard
Flash point data for 4-Methylaniline hydrochloride are not available, but 4-Methylaniline hydrochloride is probably combustible.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also p-TOLUIDINE.
Purification Methods
Crystallise the salt from MeOH containing a few drops of conc HCl or aqueous EtOH. Dry it under vacuum over paraffin chips. [Beilstein 12 II 587, 12 III 2021, 12 IV 1869.]
4-Methylaniline hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
View Lastest Price from 4-Methylaniline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4-Methylaniline hydrochloride
540-23-8
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-06 | 4-Methylaniline hydrochloride
540-23-8
|
$1.00 | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- 4-Methylaniline hydrochloride
540-23-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-Methylaniline hydrochloride
540-23-8
- $1.00
- 95%-99%
- Career Henan Chemical Co
