Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-Bromo-2(1H)-quinolone

6-Bromo-2(1H)-quinolone

6-Bromo-2(1H)-quinolone Structure
6-Bromo-2(1H)-quinolone structure
CAS No.
1810-66-8
Chemical Name:
6-Bromo-2(1H)-quinolone
Synonyms
6-BROMOQUINOLIN-2(1H)-ONE;6-bromoquinolin-2-ol;6-BROMO-2-QUINOLONE;6-BroMo-1H-quinolin-2-one;2-Hydroxy-6-bromoquinoline;P-524;109404;6-Bromocarbostyril;6-Bromo-2-quinolinol;6-Bromo-2-quinolinone
CBNumber:
CB9763838
Molecular Formula:
C9H6BrNO
Molecular Weight:
224.05
MDL Number:
MFCD08703169
MOL File:
1810-66-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:56:35
Request For Quotation

6-Bromo-2(1H)-quinolone Properties

Melting point 278-280C
Boiling point 393.8±42.0 °C(Predicted)
Density 1.620±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO
pka 10.76±0.70(Predicted)
form Solid
color Beige
InChI InChI=1S/C9H6BrNO/c10-7-2-3-8-6(5-7)1-4-9(12)11-8/h1-5H,(H,11,12)
InChIKey YLAFBGATSQRSTB-UHFFFAOYSA-N
SMILES N1C2=C(C=C(Br)C=C2)C=CC1=O
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P501
Hazard Codes  Xn
Risk Statements  22-41
Safety Statements  26-39
WGK Germany  3
HS Code  2933499090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
NFPA 704
1
2 0

6-Bromo-2(1H)-quinolone price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich BBO000085 2-Hydroxy-6-bromoquinoline Aldrich 1810-66-8 1g $230 2026-04-30 Buy
TRC TRC-B686950-1G 6-Bromo-2(1H)-quinolinone 1810-66-8 1g $123 2026-06-03 Buy
AstaTech SC2991 6-BROMOQUINOLIN-2(1H)-ONE 95% 1810-66-8 1G $32 2026-04-30 Buy
AstaTech SC2991 6-BROMOQUINOLIN-2(1H)-ONE 95% 1810-66-8 5G $95 2026-04-30 Buy
AstaTech SC2991 6-BROMOQUINOLIN-2(1H)-ONE 95% 1810-66-8 25G $284 2026-04-30 Buy
Product number Packaging Price Buy
BBO000085 1g $230 Buy
TRC-B686950-1G 1g $123 Buy
SC2991 1G $32 Buy
SC2991 5G $95 Buy
SC2991 25G $284 Buy

6-Bromo-2(1H)-quinolone Chemical Properties, Uses, Production

Chemical Properties

Beige Solid

Uses

6-Bromo-2(1H)-quinolinone is a useful intermediate for the synthesis of other quinoline derivatives.

Synthesis

(2E)-N-(4-Bromophenyl)-3-ethoxy-2-propenamide

327058-51-5

6-BROMO-2(1H)-QUINOLONE

1810-66-8

General procedure for the synthesis of 6-bromoquinolin-2(1H)-one from the compound (CAS:327058-51-5): 6-bromo-2(1H)-quinolinone (6.0 g, 22.2 mmol) was dissolved in concentrated H2SO4 (30 mL) and the reaction was heated in an oil bath at 100 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and quenched with ice water. The precipitate precipitated was collected by filtration, washed with water and subsequently dried under vacuum to afford 6-bromoquinolin-2(1H)-one as a white solid (4.8 g, 97% yield). Mass spectrum (ES+) m/e 225 [M+H]+.

References

[1] Patent: WO2006/132739, 2006, A2. Location in patent: Page/Page column 35-36
[2] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 6, p. 508 - 518
[3] European Journal of Medicinal Chemistry, 2000, vol. 35, # 10, p. 931 - 940
[4] Journal of Medicinal Chemistry, 2005, vol. 48, # 1, p. 306 - 311

6-Bromo-2(1H)-quinolone synthesis

327058-51-5
1810-66-8
Synthesis of 6-Bromo-2(1H)-quinolone from (2E)-N-(4-Bromophenyl)-3-ethoxy-2-propenamide

6-Bromo-2(1H)-quinolone Preparation Products And Raw materials

Raw materials

(2E)-N-(4-Bromophenyl)-3-ethoxy-2-propenamide 6-bromo-2-methoxyquinoline N-(4-bromophenyl)cinnamamide 4-Bromo-2-iodoaniline 6-Bromoquinoline
2-Propenamide, N-(4-bromophenyl)-3-ethoxy- Sulfuric acid 4-Bromoaniline 2-Propenamide, N-(4-bromophenyl)-3-methoxy-, (2E)- Ethyl acrylate

1of2

Preparation Products

2-Chloroquinoline-6-carbaldehyde 6-Bromoquinolin-2-amine 6-(1-Pyrazolyl)-2-quinolone

6-Bromo-2(1H)-quinolone Suppliers

Global Suppliers ( 208)
Supplier Tel Email Country ProdList Advantage
Shanghai Suifu Chemical Technology CO.,LTD. 33738187 19945655289 suifuchemical@163.com China 500 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shangchem Co., Ltd. +86-21-68182121 China 881 52
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 28-83379370 13880556291 tcy@tcypharm.com China 509 57
Supplier Advantage
Shanghai Suifu Chemical Technology CO.,LTD. 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60
Jia Xing Isenchem Co.,Ltd 66
Shangchem Co., Ltd. 52
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 57

View Latest Price from 6-Bromo-2(1H)-quinolone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-BROMO-2(1H)-QUINOLONE pictures 2026-08-20 6-BROMO-2(1H)-QUINOLONE
1810-66-8
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
6-BROMO-2(1H)-QUINOLONE pictures 2019-07-07 6-BROMO-2(1H)-QUINOLONE
1810-66-8
 $1.00 1KG 99% 100kg Career Henan Chemical Co
6-Bromo-2(1H)-quinolone;2-Hydroxy-6-bromoquinoline;6-Bromo-2(1H)-quinolinone ada@tuskwei.com pictures 2018-09-26 6-Bromo-2(1H)-quinolone;2-Hydroxy-6-bromoquinoline;6-Bromo-2(1H)-quinolinone ada@tuskwei.com
1810-66-8
 $3.00 1G 99% 7000g/day ada@tuskwei.com whatsapp;+08617197824028 Hebei Jiangkai Trading Co., Ltd

6-Bromo-2(1H)-quinolone Spectrum

6-BROMO-2(1H)-QUINOLONE(1810-66-8)1HNMR

1810-66-8 (6-Bromo-2(1H)-quinolone) Related Search:

6-BroMoquinoline-2-carbaldehyde 6-Bromoquinazoline 6-BroMoquinoline-3-carbonitrile 3-Quinolinecarboxaldehyde, 6-broMo- 6-BroMoquinolin-3-aMine
6-bromoquinoxalin-2-amine 6-bromoquinoxalin-2(1H)-one 6-Bromoquinoxaline 6-Bromo-quinazolin-4-ylamine 6-Bromoquinoline-3-carboxylic acid
6-Bromo-2(1H)-quinolone 6-Bromoquinoline 6-Bromo-4-hydroxyquinoline 6-bromo-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione 6-Bromo-2-hydroxyquinoline-4-carboxylic acid
6-Bromo-4-methylquinolin-2(1H)-one CHEMBRDG-BB 6599056 6-Bromo-4-methyl-1-phenylanthrapyridone

1of4

6-BROMO-2-HYDROXYQUINOLINE 6-Bromo-2(1H)-quinolinone 6-Bromo-2-quinolinol 6-Bromocarbostyril 6-Bromo-2-hydroxyquinoline 98% 109404 6-Bromo-2-quinolinone 2-Hydroxy-6-bromoquinoline 6-broMo-1,2-dihydroquinolin-2-one 6-BROMO-2(1H)-QUINOLONE、6-BroMoquinolin-2(1H)-one 6-broMo-2,3-dihydroquinolin-2-one 6-Bromoquinolin-2-ol, 6-Bromo-2-hydroxy-1-azanaphthalene 6-bromoquinolin-2-one 2(1H)-Quinolinone, 6-bromo- 6-BROMO-2(1H)-QUINOLONE 1810-66-8 6-BROMO-2(1H)-QUINOLONE ISO 9001：2015 REACH P-524 6-BROMOQUINOLIN-2(1H)-ONE 6-BROMO-2-QUINOLONE 6-BroMo-1H-quinolin-2-one 6-bromoquinolin-2-ol 6-Bromo-2(1H)-quinolone 1810-66-8 Aromatics Compounds CHIRAL CHEMICALS Aromatics Heterocycles