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2,5-Dimethylaniline

2,5-Dimethylaniline Structure
2,5-Dimethylaniline structure
CAS No.
95-78-3
Chemical Name:
2,5-Dimethylaniline
Synonyms
2,5-XYLIDINE;P-XYLIDINE;2,5-Dimethylbenzenamine;Benzenamine, 2,5-dimethyl-;ai3-16559;AKOS 91126;para-xylidine;2-amino-p-xylene;AKOS BBS-00003675;2-Amino-1,4-xylene
CBNumber:
CB9854710
Molecular Formula:
C8H11N
Molecular Weight:
121.18
MDL Number:
MFCD00007743
MOL File:
95-78-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:22:28
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2,5-Dimethylaniline Properties

Melting point 11.5 °C(lit.)
Boiling point 218 °C(lit.)
Density 0.973 g/mL at 25 °C(lit.)
vapor pressure 20Pa
refractive index n20/D 1.559(lit.)
Flash point 201 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly)
form Liquid
pka pK1:4.53(+1) (25°C)
color Clear yellow to red-brown
Viscosity 13.23mm2/s
Water Solubility <0.1 g/100 mL at 18 ºC
Merck 14,10084
BRN 2205178
Henry's Law Constant 2.3×100 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
InChI 1S/C8H11N/c1-6-3-4-7(2)8(9)5-6/h3-5H,9H2,1-2H3
InChIKey VOWZNBNDMFLQGM-UHFFFAOYSA-N
SMILES Cc1ccc(C)c(N)c1
LogP 1.83
CAS DataBase Reference 95-78-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII XWK0W8DA04
IARC 3 (Vol. 16, Sup 7) 1987
NIST Chemistry Reference Benzenamine, 2,5-dimethyl-(95-78-3)
EPA Substance Registry System 2,5-Dimethylaniline (95-78-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300+H310+H330-H315-H319-H373-H411
Precautionary statements  P501-P273-P270-P262-P260-P271-P264-P280-P284-P391-P314-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P310-P304+P340+P310-P403+P233-P405
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  T,N,Xn
Risk Statements  23/24/25-33-51/53-48/20
Safety Statements  28-36/37-45-61-28A
RIDADR  UN 1711 6.1/PG 2
WGK Germany  3
RTECS  ZE9100000
F  8-10-23
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  II
HS Code  29214910
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 2
STOT RE 2
Hazardous Substances Data 95-78-3(Hazardous Substances Data)
REACH Registrations Active
Limited Quantities 100ml (liquid) or 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

2,5-Dimethylaniline price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 102253 2,5-Dimethylaniline 99% 95-78-3 100ml $67.7 2026-04-30 Buy
TCI Chemical D0668 2,5-Dimethylaniline >97.0%(GC) 95-78-3 25g $21 2026-04-30 Buy
TCI Chemical D0668 2,5-Dimethylaniline >97.0%(GC) 95-78-3 500g $228 2026-04-30 Buy
Apolloscientific OR7001 2,5-Dimethylaniline 95% 95-78-3 1g $21 2026-06-04 Buy
Apolloscientific OR7001 2,5-Dimethylaniline 95% 95-78-3 5g $24 2026-06-04 Buy
Product number Packaging Price Buy
102253 100ml $67.7 Buy
D0668 25g $21 Buy
D0668 500g $228 Buy
OR7001 1g $21 Buy
OR7001 5g $24 Buy

2,5-Dimethylaniline Chemical Properties,Uses,Production

Chemical Properties

clear yellow to red-brown liquid

Uses

The uses are the same as those of xylidines.

Uses

2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.

Uses

2,5-Dimethylaniline was used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.

General Description

Dark brown liquid.

Air & Water Reactions

2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,5-Dimethylaniline is combustible.

Safety Profile

Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]

2,5-Dimethylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Dimethylphenol 2,5-DIMETHYLBENZONITRILE 2-Fluoro-p-Xylene 2,5-DIMETHYLPHENYL ISOCYANATE 3-Fluoro-4-methylbenzoic acid
2,5-DIMETHYLANISOLE C.I. Direct Orange 35 disodium 7-(acetylamino)-3-[[4-[(4-chloro-2-sulphonatophenyl)azo]-2,5-dimethylphenyl]azo]-4-hydroxynaphthalene-2-sulphonate 4-Hydroxy-7-phenylamino-3-[[2,5-dimethyl-4-[(4-methyl-2-sodiosulfophenyl)azo]phenyl]azo]naphthalene-2-sulfonic acid sodium salt tetrasodium 5,5'-[iminobis[(1-hydroxy-3-sulphonato-6,2-naphthylene)azo(2,5-dimethoxy-4,1-phenylene)azo]]bis(salicylate)
1,5-Naphthalenedisulfonic acid, 3-[[4-[[4-[(4-amino-2,5-dimethylphenyl)azo]-6(or 7)-sulfo-1-naphthalenyl]azo]-1-naphthalenyl]azo]-, trisodium salt Direct Orange 46 disodium 7-amino-4-hydroxy-3-[[5-hydroxy-6-(phenylazo)-7-sulphonato-2-naphthyl]azo]naphthalene-2-sulphonate C.I. Reactive orange 35 Naphtho[2,1-d]thiazole-8-sulfonic acid, 2-(4-aminophenyl)-7-[[4-[(4-chloro-2-sulfophenyl)azo]-2,5-dimethylphenyl]azo]-6-hydroxy-, disodium salt
REACTIVE BROWN 2 2-Naphthalenesulfonic acid, 3-[[2,5-dimethyl-4-[(4-sulfophenyl)azo]phenyl]azo]-4-hydroxy-7-[[[(5-hydroxy-7-sulfo-2-naphthalenyl)amino]carbonyl]amino]-, trisodium salt 3-[[2,5-Dimethyl-4-[(1-hydroxy-6-phenylamino-3-sodiosulfo-2-naphthalenyl)azo]phenyl]azo]naphthalene-1,5-disulfonic acid disodium salt Solvent Red 26 Benzenesulfonic acid, 5-[(4-amino-2,5-dimethylphenyl)azo]-2-methoxy-, monosodium salt, reaction products with 2,2'-(1,2-ethenediyl)bis[5-nitrobenzenesulfonic acid], reduced

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2,5-Dimethylaniline Suppliers

Global( 326)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 18080918076 800078821@qq.com China 9706 55
tonsooh 027-83238443 13343438265 1569708153@qq.com China 4987 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Supplier Advantage
Chengdu Ai Keda Chemical Technology Co., Ltd. 55
tonsooh 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Beijing Isomersyn Technology CO;LTD 57
Shandong Xiya Chemical Co., Ltd 57

View Lastest Price from 2,5-Dimethylaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dimethylaniline pictures 2026-05-28 2,5-Dimethylaniline
95-78-3
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2,5-Dimethylaniline pictures 2019-07-06 2,5-Dimethylaniline
95-78-3
 $8.00 1 kg 98% 10MT Career Henan Chemical Co

2,5-Dimethylaniline Spectrum

2,5-Dimethylaniline(95-78-3)MS2,5-Dimethylaniline(95-78-3)1HNMR2,5-Dimethylaniline(95-78-3)13CNMR2,5-Dimethylaniline(95-78-3)IR12,5-Dimethylaniline(95-78-3)IR22,5-Dimethylaniline(95-78-3)Raman

95-78-3(2,5-Dimethylaniline)Related Search:

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ai3-16559 Aniline, 2,5-dimethyl- para-xylidine 2,5-Dimethylaniline,99% 2,5-DIMETHYLANILINE / 2,5-XYLIDINE 2,5-DIMETHYLBENZAMINE AKOS BBS-00003675 AKOS 91126 5-METHYL-O-TOLUIDINE 6-METHYL-M-TOLUIDINE 3,6-DIMETHYLANILINE 3-amino-1,4-dimethylbenzene 1-AMINO-2,5-DIMETHYLBENZENE 2-AMINO-4-METHYLTOLUENE 2-AMINO-1,4-DIMETHYLBENZENE 2,5-DIMETHYLANILINE 2,5-Dimethylaniline, 98+% 2,5-Xylidine (NH2=1) 2,5-dimethyl-anilin 2,5-dimethyl-benzenamin 2,5-dimethyl-Benzenamine 2,5-Dimethylbenzeneamine 2,5-Dimethylphenylamine 2-amino-1,4-dimethyl-benzen 2-Amino-1,4-xylene 2-amino-p-xylene 5-Amino-1,4-dimethylbenzene 2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-Dimethylaniline,2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-DiMethylaniline, 99% 100GR 2,5-DiMethylaniline, 99% 5GR 2,5-Xylidine p-Xylidine 2,5-DIMETHYLANILINE FOR SYNTHESIS 2,5-two Methyl aniline 2,5-Dimethylaniline > TIANFU CHEM-2,5-Dimethylaniline 2,5-XYLIDINE 2,5-Dimethylbenzenamine Benzenamine, 2,5-dimethyl- P-XYLIDINE 95-78-3 95783 Amines Building Blocks C8 Nitrogen Compounds Organic Building Blocks Phenyls & Phenyl-Het Anilines, Aromatic Amines and Nitro Compounds Amines Phenyls & Phenyl-Het Intermediates