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2,5-Dimethylaniline

2,5-Dimethylaniline structure

CAS No.: 95-78-3

Chemical Name:: 2,5-Dimethylaniline

Synonyms: 2,5-XYLIDINE;ai3-16559;AKOS 91126;P-XYLIDINE;para-xylidine;2-amino-p-xylene;AKOS BBS-00003675;2-Amino-1,4-xylene;3,6-DIMETHYLANILINE;2,5-DIMETHYLANILINE

CBNumber:: CB9854710

Molecular Formula:: C8H11N

Molecular Weight:: 121.18

MDL Number:: MFCD00007743

MOL File:: 95-78-3.mol

MSDS File:: SDS

Last updated:2026-01-13 11:27:11

Product description	Number	Pack Size	Price
2,5-Dimethylaniline 99%	102253	100ml	$63.5
2,5-Dimethylaniline >97.0%(GC)	D0668	25g	$21
2,5-Dimethylaniline >97.0%(GC)	D0668	500g	$228
2,5-Dimethylaniline(2,5-Xylidine)	X749700	10g	$135
2,5-Dimethylaniline(2,5-Xylidine)	X749700	25g	$155
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2,5-Dimethylaniline Properties

Melting point	11.5 °C(lit.)
Boiling point	218 °C(lit.)
Density	0.973 g/mL at 25 °C(lit.)
vapor pressure	20Pa
refractive index	n20/D 1.559(lit.)
Flash point	201 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly)
pka	pK1:4.53(+1) (25°C)
form	Liquid
color	Clear yellow to red-brown
Viscosity	13.23mm2/s
Water Solubility	<0.1 g/100 mL at 18 ºC
Merck	14,10084
BRN	2205178
InChI	1S/C8H11N/c1-6-3-4-7(2)8(9)5-6/h3-5H,9H2,1-2H3
InChIKey	VOWZNBNDMFLQGM-UHFFFAOYSA-N
SMILES	Cc1ccc(C)c(N)c1
LogP	1.83
CAS DataBase Reference	95-78-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	XWK0W8DA04
IARC	3 (Vol. 16, Sup 7) 1987
NIST Chemistry Reference	Benzenamine, 2,5-dimethyl-(95-78-3)
EPA Substance Registry System	2,5-Dimethylaniline (95-78-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H301+H311+H331-H373-H411

Precautionary statements

P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

T,N,Xn

Risk Statements

23/24/25-33-51/53-48/20

Safety Statements

28-36/37-45-61-28A

RIDADR

UN 1711 6.1/PG 2

WGK Germany

RTECS

ZE9100000

8-10-23

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

HS Code

29214910

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 2
STOT RE 2

Hazardous Substances Data

95-78-3(Hazardous Substances Data)

Limited Quantities

100ml (liquid) or 0.5 Kg (solid)

Excepted Quantities

Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	1
3		0

2,5-Dimethylaniline price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	102253	2,5-Dimethylaniline 99%	95-78-3	100ml	$63.5	2025-07-31	Buy
TCI Chemical	D0668	2,5-Dimethylaniline >97.0%(GC)	95-78-3	25g	$21	2025-07-31	Buy
TCI Chemical	D0668	2,5-Dimethylaniline >97.0%(GC)	95-78-3	500g	$228	2025-07-31	Buy
TRC	X749700	2,5-Dimethylaniline(2,5-Xylidine)	95-78-3	10g	$135	2021-12-16	Buy
TRC	X749700	2,5-Dimethylaniline(2,5-Xylidine)	95-78-3	25g	$155	2021-12-16	Buy

Product number	Packaging	Price	Buy
102253	100ml	$63.5	Buy
D0668	25g	$21	Buy
D0668	500g	$228	Buy
X749700	10g	$135	Buy
X749700	25g	$155	Buy

2,5-Dimethylaniline Chemical Properties,Uses,Production

Chemical Properties

clear yellow to red-brown liquid

Uses

The uses are the same as those of xylidines.

Uses

2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.

Uses

2,5-Dimethylaniline was used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.

General Description

Dark brown liquid.

Air & Water Reactions

2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,5-Dimethylaniline is combustible.

Safety Profile

Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]

2,5-Dimethylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Dimethylphenol 2,5-DIMETHYLBENZONITRILE 2-Fluoro-p-Xylene 2,5-DIMETHYLPHENYL ISOCYANATE 3-Fluoro-4-methylbenzoic acid

2,5-DIMETHYLANISOLE C.I. Direct Orange 35 disodium 7-(acetylamino)-3-[[4-[(4-chloro-2-sulphonatophenyl)azo]-2,5-dimethylphenyl]azo]-4-hydroxynaphthalene-2-sulphonate 4-Hydroxy-7-phenylamino-3-[[2,5-dimethyl-4-[(4-methyl-2-sodiosulfophenyl)azo]phenyl]azo]naphthalene-2-sulfonic acid sodium salt tetrasodium 5,5'-[iminobis[(1-hydroxy-3-sulphonato-6,2-naphthylene)azo(2,5-dimethoxy-4,1-phenylene)azo]]bis(salicylate)

1,5-Naphthalenedisulfonic acid, 3-[[4-[[4-[(4-amino-2,5-dimethylphenyl)azo]-6(or 7)-sulfo-1-naphthalenyl]azo]-1-naphthalenyl]azo]-, trisodium salt Direct Orange 46 disodium 7-amino-4-hydroxy-3-[[5-hydroxy-6-(phenylazo)-7-sulphonato-2-naphthyl]azo]naphthalene-2-sulphonate C.I. Reactive orange 35 Naphtho[2,1-d]thiazole-8-sulfonic acid, 2-(4-aminophenyl)-7-[[4-[(4-chloro-2-sulfophenyl)azo]-2,5-dimethylphenyl]azo]-6-hydroxy-, disodium salt

REACTIVE BROWN 2 2-Naphthalenesulfonic acid, 3-[[2,5-dimethyl-4-[(4-sulfophenyl)azo]phenyl]azo]-4-hydroxy-7-[[[(5-hydroxy-7-sulfo-2-naphthalenyl)amino]carbonyl]amino]-, trisodium salt 3-[[2,5-Dimethyl-4-[(1-hydroxy-6-phenylamino-3-sodiosulfo-2-naphthalenyl)azo]phenyl]azo]naphthalene-1,5-disulfonic acid disodium salt Solvent Red 26 Benzenesulfonic acid, 5-[(4-amino-2,5-dimethylphenyl)azo]-2-methoxy-, monosodium salt, reaction products with 2,2'-(1,2-ethenediyl)bis[5-nitrobenzenesulfonic acid], reduced

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2,5-Dimethylaniline Suppliers

Global( 331)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5242	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21599	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Anhui Royal Chemical Co., Ltd.	+86-025-86655873 +8613962173137	marketing@royal-chem.com	China	200	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Anhui Royal Chemical Co., Ltd.	55
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2,5-Dimethylaniline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-26	2,5-Dimethylaniline 95-78-3	US $5.00-2.00 / KG	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
	2019-07-06	2,5-Dimethylaniline 95-78-3	US $8.00 / kg	1 kg	98%	10MT	Career Henan Chemical Co

2,5-Dimethylaniline
95-78-3
US $5.00-2.00 / KG
99%
Hebei Chuanghai Biotechnology Co,.LTD

2,5-Dimethylaniline
95-78-3
US $8.00 / kg
98%
Career Henan Chemical Co

2,5-Dimethylaniline Spectrum

2,5-Dimethylaniline(95-78-3)MS 2,5-Dimethylaniline(95-78-3)¹HNMR 2,5-Dimethylaniline(95-78-3)¹³CNMR 2,5-Dimethylaniline(95-78-3)IR1 2,5-Dimethylaniline(95-78-3)IR2 2,5-Dimethylaniline(95-78-3)Raman

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ai3-16559 Aniline, 2,5-dimethyl- para-xylidine P-XYLIDINE 2,5-Dimethylaniline,99% 2,5-DIMETHYLANILINE / 2,5-XYLIDINE Benzenamine, 2,5-dimethyl- 2,5-DIMETHYLBENZAMINE AKOS BBS-00003675 AKOS 91126 5-METHYL-O-TOLUIDINE 6-METHYL-M-TOLUIDINE 3,6-DIMETHYLANILINE 3-amino-1,4-dimethylbenzene 1-AMINO-2,5-DIMETHYLBENZENE 2-AMINO-4-METHYLTOLUENE 2-AMINO-1,4-DIMETHYLBENZENE 2,5-XYLIDINE 2,5-DIMETHYLANILINE 2,5-Dimethylaniline, 98+% 2,5-Xylidine (NH2=1) 2,5-dimethyl-anilin 2,5-dimethyl-benzenamin 2,5-Dimethylbenzenamine 2,5-dimethyl-Benzenamine 2,5-Dimethylbenzeneamine 2,5-Dimethylphenylamine 2-amino-1,4-dimethyl-benzen 2-Amino-1,4-xylene 2-amino-p-xylene 5-Amino-1,4-dimethylbenzene 2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-Dimethylaniline,2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-DiMethylaniline, 99% 100GR 2,5-DiMethylaniline, 99% 5GR 2,5-Xylidine p-Xylidine 2,5-DIMETHYLANILINE FOR SYNTHESIS 2,5-two Methyl aniline 2,5-Dimethylaniline > TIANFU CHEM-2,5-Dimethylaniline 95-78-3 95783 Amines Building Blocks C8 Nitrogen Compounds Organic Building Blocks Phenyls & Phenyl-Het Anilines, Aromatic Amines and Nitro Compounds Amines Phenyls & Phenyl-Het Intermediates