S-(hydrogen malonyl)coenzyme A
- CAS No.
- 524-14-1
- Chemical Name:
- S-(hydrogen malonyl)coenzyme A
- Synonyms
- malony-coa;Malonyl-CoA;S-Malonyl-CoA;Malonyl Coenzyme A;Malonyl-CoA-sodium-salt;S-(Carboxyacetyl)coenzyme A;S-(hydrogen malonyl)coenzyme A;Coenzyme A, S-(hydrogen propanedioate);coenzyme A malonyl derivative, tetralithium salt;Adenosine 5'-[diphosphoric acid β-[(R)-4-[[2-[[2-(carboxyacetylthio)ethyl]carbamoyl]ethyl]amino]-4-oxo-3-hydroxy-2,2-dimethylbutyl]]3'-phosphoric acid
- CBNumber:
- CB9908893
- Molecular Formula:
- C24H38N7O19P3S
- Molecular Weight:
- 853.58
- MDL Number:
- MFCD00870167
- MOL File:
- 524-14-1.mol
- MSDS File:
- SDS
Density | 1.95±0.1 g/cm3(Predicted) |
---|---|
pka | 1.16±0.50(Predicted) |
FDA UNII | LNB9YCJ9F9 |
S-(hydrogen malonyl)coenzyme A Chemical Properties,Uses,Production
Uses
Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1[1][2].
Definition
ChEBI: The S-malonyl derivative of coenzyme A.
IC 50
Human Endogenous Metabolite
References
[1] Folmes CD, et L. Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. Cardiovasc Res. 2007 Jan 15;73(2):278-87. DOI:10.1016/j.cardiores.2006.10.008
[2] Thupari JN, et al. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. Biochem Biophys Res Commun. 2001 Jul 13;285(2):217-23. DOI:10.1006/bbrc.2001.5146
[3] Zammit VA. Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro. Biochem J. 1983 Mar 15;210(3):953-6. DOI:10.1042/bj2100953
S-(hydrogen malonyl)coenzyme A Preparation Products And Raw materials
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View Lastest Price from S-(hydrogen malonyl)coenzyme A manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2020-11-17 | S-(hydrogen malonyl)coenzyme A
524-14-1
|
US $25.00 / Kg/Bag | 25Kg/Bag | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd |
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- S-(hydrogen malonyl)coenzyme A
524-14-1
- US $25.00 / Kg/Bag
- 99%
- Longyan Tianhua Biological Technology Co., Ltd