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Methyl 5-bromo-2-chloroisonicotinate

CAS No.
886365-28-2
Chemical Name:
Methyl 5-bromo-2-chloroisonicotinate
Synonyms
Methyl 5-bromo-2-chloroisonicotite;Methyl 5-bromo-2-chloroisonicotinate;Methyl 5-bromo-2-chloroisonicotinate 98%;Methyl 5-bromo-2-chloropyridine-4-carboxylate;methyl 5-bromo-2-chloro-4-pyridinecarboxylate;5-bromo-2-chloro-3-methyl-4-pyridinecarboxylate;5-bromo-2-chloro-pyridin-4-carboxylic acid methyl ester;5-Bromo-2-chloro-4-pyridinecarboxylic acid methyl ester;4-Pyridinecarboxylic acid, 5-broMo-2-chloro-, Methyl ester;Methyl 5-bromo-2-chloropyridine-4-carboxylate, 5-Bromo-2-chloro-4-(methoxycarbonyl)pyridine
CBNumber:
CB9956465
Molecular Formula:
C7H5BrClNO2
Molecular Weight:
250.48
MDL Number:
MFCD07375113
MOL File:
886365-28-2.mol
MSDS File:
SDS
Last updated:2026-05-28 05:22:38

Methyl 5-bromo-2-chloroisonicotinate Properties

Boiling point 286.5±35.0℃ (760 Torr)
Density 1.684±0.06 g/cm3 (20 ºC 760 Torr)
Flash point 127.1±25.9℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -3.54±0.10(Predicted)
Appearance Off-white to light yellow Solid-liquid mixture
InChI InChI=1S/C7H5BrClNO2/c1-12-7(11)4-2-6(9)10-3-5(4)8/h2-3H,1H3
InChIKey ZGVAWYBJGMOKBV-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(Br)C(C(OC)=O)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2933399990

Methyl 5-bromo-2-chloroisonicotinate price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00367S 5-bromo-2-chloro-4-Pyridinecarboxylicacid methyl ester 97% 886365-28-2 250mg $5 2026-05-28 Buy
aablocks AA00367S 5-bromo-2-chloro-4-Pyridinecarboxylicacid methyl ester 97% 886365-28-2 1g $7 2026-05-28 Buy
aablocks AA00367S 5-bromo-2-chloro-4-Pyridinecarboxylicacid methyl ester 97% 886365-28-2 5g $19 2026-05-28 Buy
aablocks AA00367S 5-bromo-2-chloro-4-Pyridinecarboxylicacid methyl ester 97% 886365-28-2 10g $34 2026-05-28 Buy
aablocks AA00367S 5-bromo-2-chloro-4-Pyridinecarboxylicacid methyl ester 97% 886365-28-2 25g $71 2026-05-28 Buy
Product number Packaging Price Buy
AA00367S 250mg $5 Buy
AA00367S 1g $7 Buy
AA00367S 5g $19 Buy
AA00367S 10g $34 Buy
AA00367S 25g $71 Buy

Methyl 5-bromo-2-chloroisonicotinate Chemical Properties,Uses,Production

Synthesis

To a 5000 mL three-necked flask, add 3500 mL of the above already prepared methanol solution of hydrogen chloride, 350 g of 5-bromo-2-chloroisonicotinic acid, raise the temperature to 40C and stir the reaction, track the reaction by liquid chromatography, and stop the reaction when the product, methyl 5-bromo-2-chloroisonicotinate, is greater than 85% by liquid chromatography, and the content of the methyl 5-bromo-2-methoxyisonicotinate by-product (3) is less than 1%. Reaction. Neutralize the system with solid sodium bicarbonate to neutral under stirring, filter, drain, rinse the filter cake with methanol, combine the filtrates and concentrate to obtain a brownish-red liquid 320 g, high vacuum distillation, collect 40-60 Pa, 70-75 fractions, obtain a colorless liquid 5-bromo-2-chloroisonicotinic acid methyl ester (296 g), content of 98.9%.

Methyl 5-bromo-2-chloroisonicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 115)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai yuanzuo medical technology co., LTD 021-31775309; 15221510662 yi_shiyan@yuanzuopharm.com China 139 58
Zhuhai Aobokai Biomedical Technology Co., Ltd. 400-0628126 sales-team@aobchem.com.cn China 49995 58
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shenyang Comrade Chemical Co., Ltd. +86(24) 31938773(O) sales@co-chem.com China 225 62
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55

View Lastest Price from Methyl 5-bromo-2-chloroisonicotinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 5-bromo-2-chloroisonicotinate pictures 2020-01-09 Methyl 5-bromo-2-chloroisonicotinate
886365-28-2
$2.00 1g 98%min Career Henan Chemical Co

Methyl 5-bromo-2-chloroisonicotinate Spectrum

Methyl 5-bromo-2-chloropyridine-4-carboxylate, 5-Bromo-2-chloro-4-(methoxycarbonyl)pyridine 4-Pyridinecarboxylic acid, 5-broMo-2-chloro-, Methyl ester 5-Bromo-2-chloro-4-pyridinecarboxylic acid methyl ester Methyl 5-bromo-2-chloroisonicotite 5-bromo-2-chloro-pyridin-4-carboxylic acid methyl ester Methyl 5-bromo-2-chloroisonicotinate Methyl 5-bromo-2-chloropyridine-4-carboxylate Methyl 5-bromo-2-chloroisonicotinate 98% methyl 5-bromo-2-chloro-4-pyridinecarboxylate 5-bromo-2-chloro-3-methyl-4-pyridinecarboxylate 886365-28-2 88635-28-2 78686-79-1 blocks Bromides Carboxes Pyridines