3-Hydroxythiophene-2-carboxylic acid
- CAS No.
- 5118-07-0
- Chemical Name:
- 3-Hydroxythiophene-2-carboxylic acid
- Synonyms
- 3-Hydroxy-2-thiophenecarboxylic acid;3-Hydroxythiophene-2-carboxylic acid;2-Thiophenecarboxylic acid, 3-hydroxy-;2-(dihydroxymethylidene)-3-thiophenone;3-Hydroxythiophene-2-carboxylic acid 97%;2-Carboxy-3-hydroxythiophene, 3-Hydroxy-2-thenoic acid;3-Hydroxythiophene-2-carboxylic acid ISO 9001：2015 REACH
- CBNumber:
- CB9956788
- Molecular Formula:
- C5H4O3S
- Molecular Weight:
- 144.15
- MDL Number:
- MFCD09414719
- MOL File:
- 5118-07-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 2934999090 |
3-Hydroxythiophene-2-carboxylic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR2594 | 3-Hydroxythiophene-2-carboxylic acid 95% | 5118-07-0 | 100mg | $111 | 2026-06-04 | Buy |
| Apolloscientific | OR2594 | 3-Hydroxythiophene-2-carboxylic acid 95% | 5118-07-0 | 250mg | $160 | 2026-06-04 | Buy |
| Apolloscientific | OR2594 | 3-Hydroxythiophene-2-carboxylic acid 95% | 5118-07-0 | 500mg | $282 | 2026-06-04 | Buy |
| Apolloscientific | OR2594 | 3-Hydroxythiophene-2-carboxylic acid 95% | 5118-07-0 | 1g | $453 | 2026-06-04 | Buy |
| Activate Scientific | AS118502 | 3-Hydroxythiophene-2-carboxylic acid 97% | 5118-07-0 | 1g | $323 | 2026-06-04 | Buy |
3-Hydroxythiophene-2-carboxylic acid Chemical Properties, Uses, Production
Uses
3-Hydroxythiophene-2-carboxylic acid (cas# 5118-07-0) is a useful research chemical. This compound is useful because furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.
Synthesis
186588-88-5
5118-07-0
General procedure for the synthesis of 3-hydroxythiophene-2-carboxylic acid from 3-benzyloxythiophene-2-carboxylic acid: a) 3-benzyloxythiophene-2-carboxylic acid (1.0 g) was hydrogenated with 10% palladium-carbon catalyst (1.8 g) in a mixture of ethanol (150 mL) and 2N hydrochloric acid (4.5 mL) for 2 hours at 45 psi hydrogen pressure. Upon completion of the reaction, the mixture was filtered through a layer of diatomaceous earth and the filtrate was concentrated under vacuum to afford 3-hydroxythiophene-2-carboxylic acid (600 mg, 98% yield) as an off-white solid product. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 6.78 (d, 1H), 7.49 (d, 1H). Mass spectrometry (APCI) showed m/z=145 (M+1).LC/MS analysis showed a retention time of 1.15 min.
References
[1] Patent: WO2007/1225, 2007, A1. Location in patent: Page/Page column 16
3-Hydroxythiophene-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Hydroxythiophene-2-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Hekang Biotechnology Co., Ltd. | 17721021104 18939837085 | 2880152141@qq.com | China | 1840 | 55 |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1576 | 58 | |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Henan CoreyChem Co., Ltd | 0371-86658258 | info@coreychem.com | China | 10442 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from 3-Hydroxythiophene-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-Hydroxythiophene-2-carboxylic acid
5118-07-0
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2020-01-14 | 3-Hydroxythiophene-2-carboxylic acid
5118-07-0
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 3-Hydroxythiophene-2-carboxylic acid
5118-07-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Hydroxythiophene-2-carboxylic acid
5118-07-0
- $9.80
- ≥99%
- Career Henan Chemical Co
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