6-Fluoropyridine-2-boronic acid
- CAS No.
- 916176-61-9
- Chemical Name:
- 6-Fluoropyridine-2-boronic acid
- Synonyms
- 6-Fluorpyridine-2-boronic acid;6-Fluoro-2-pyridineboronic acid;(6-fluoropyridin-2-yl)boronicaci;6-Fluoropyridin-2-ylboronic acid;(6-Fluoro-2-pyridyl)boronic acid;B-(6-Fluoro-2-pyridinyl)-boronic acid;Boronic acid, B-(6-fluoro-2-pyridinyl)-;6-Fluoropyridine-2-boronic acid ISO 9001：2015 REACH
- CBNumber:
- CB9967546
- Molecular Formula:
- C5H5BFNO2
- Molecular Weight:
- 140.91
- MDL Number:
- MFCD08705713
- MOL File:
- 916176-61-9.mol
| Boiling point | 327℃ |
|---|---|
| Density | 1.34 |
| Flash point | 152℃ |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| pka | 6.76±0.53(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C5H5BFNO2/c7-5-3-1-2-4(8-5)6(9)10/h1-3,9-10H |
| InChIKey | KUKRPJYXNBIBIT-UHFFFAOYSA-N |
| SMILES | B(C1=NC(F)=CC=C1)(O)O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| HS Code | 2933399990 |
6-Fluoropyridine-2-boronic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC412475 | 6-Fluoropyridine-2-boronic acid 95% | 916176-61-9 | 100mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC412475 | 6-Fluoropyridine-2-boronic acid 95% | 916176-61-9 | 250mg | $37 | 2026-06-04 | Buy |
| Apolloscientific | PC412475 | 6-Fluoropyridine-2-boronic acid 95% | 916176-61-9 | 1g | $92 | 2026-06-04 | Buy |
| Apolloscientific | PC412475 | 6-Fluoropyridine-2-boronic acid 95% | 916176-61-9 | 5g | $444 | 2026-06-04 | Buy |
| Activate Scientific | AS113926 | (6-Fluoropyridin-2-yl)boronic acid 95% | 916176-61-9 | 1g | $130 | 2026-06-04 | Buy |
6-Fluoropyridine-2-boronic acid Chemical Properties,Uses,Production
Synthesis
144100-07-2
916176-61-9
Under nitrogen protection, 2-bromo-6-fluoropyridine (2.5 g, 14.2 mmol, 1 eq.) and triisopropyl borate (4 mL) were dissolved in a solvent mixture of toluene (50 mL) and tetrahydrofuran (12.5 mL) and the reaction system was cooled to -78 °C. n-Butyllithium (10.8 mL, 1.6 M hexane solution) was slowly added dropwise over 1.25 hours. After the dropwise addition was completed, the reaction mixture was stirred at -78 °C for 30 min, followed by slow warming to 0 °C over 2 h. Upon completion of the reaction, the reaction was quenched with 2M aqueous hydrochloric acid solution (10 mL) and stirred at room temperature for 1 hour. The organic phase was separated, washed with 0.5 M aqueous hydrochloric acid, dried over anhydrous sodium sulfate and concentrated under a stream of nitrogen to remove the solvent. The aqueous phase was neutralized with saturated sodium bicarbonate solution and extracted with ethyl acetate, the organic phases were combined, dried over anhydrous sodium sulfate and concentrated under a stream of nitrogen to give the second product. Final isolation afforded 2-fluoropyridine-6-boronic acid as a white solid (1.27 g, 64% yield).
References
[1] Patent: WO2006/127587, 2006, A1. Location in patent: Page/Page column 95-96
6-Fluoropyridine-2-boronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai C&W New Material Co., Ltd. | 021-22062033 15921412618 | sales@c-wnewmaterial.com | China | 210 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7882 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
View Lastest Price from 6-Fluoropyridine-2-boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 6-Fluoropyridine-2-boronic acid
916176-61-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-12 | 6-Fluoropyridine-2-boronic acid
916176-61-9
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 6-Fluoropyridine-2-boronic acid
916176-61-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-Fluoropyridine-2-boronic acid
916176-61-9
- $1.00
- 99%
- Career Henan Chemical Co
