RK-682
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RK-682 속성
- 끓는 점
- 546.7±50.0 °C(Predicted)
- 밀도
- 1.073±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- 메탄올 에 용해됨
- 물리적 상태
- 담황색 고체.
- 산도 계수 (pKa)
- 1.80±0.10(Predicted)
안전
RK-682 C화학적 특성, 용도, 생산
개요
TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682 . TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B (IC50s = 8.6, 12.4, and 0.7 μM, respectively), but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces.용도
TAN 1364B (RK-682) is the most abundant analogue of a tetronic acid complex isolated from Streptomyces species, first patented by Takeda in 1993 and more formally identified by Ciba Geigy as the sodium salt of 3-hexadecanoyl-5-hydroxymethyltetronic acid. In 1995 researchers at RIKEN reported the isolation of 3-hexadecanoyl-5-hydroxymethyltetronic acid, named as RK-682. Subsequent synthesis in 2001 showed that the RIKEN RK-682 was in fact the calcium complex of TAN 1364B formed as an artefact during silica chromatography. As the complex, salt or free acid, TAN 1364B inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. However, it is unclear whether biological activity is due to the monomer (TAN 1364B) or dimeric complex (RK-682)RK-682 준비 용품 및 원자재
원자재
준비 용품
RK-682 공급 업체
글로벌( 47)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 |
anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 |
njduly@126.com | China | 3293 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 |
2881489226@qq.com | China | 89667 | 60 |
| Lynnchem | 86-(0)29-85992781 17792393971 |
info@lynnchem.com | China | 4578 | 58 |
| Novachemistry | 44-20819178-90 02081917890 |
info@novachemistry.com | United Kingdom | 4372 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 |
sales@glpbio.cn | China | 6705 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 |
sales@rrkchem.com | China | 57336 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11123 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 |
sales@mitachieve.com | China | 8857 | 58 |
RK-682 관련 검색:
디하이드로푸란-3(2H)-온 메틸(2-)테트라히드로퓨란-3-온 메틸3-옥소테트라데카노에이트 메틸3-옥소옥타데카노에이트 에틸3-옥소데카노에이트 테트로닉산 α-아세틸-γ-부틸올락톤 부탄산,2-아세틸-3-옥소- 2-FORMYL-3-OXO-부티르산에틸에스테르 3-메틸-노난-2,4-디온 메틸2-포르밀-3-옥소-프로피오네이트 메틸3-옥소헥사데카노에이트 에틸3-옥소테트라데카노에이트 프로판산,2-포르밀-3-옥소-,에틸에스테르 메틸3-옥소도데카노에이트 메틸3-옥소데카노에이트
3-Heptyldihydro-5-methyl-2(3H)-furanone
RK-682