2-Deoxy-D-glucose manufacturers and suppliers

2-Deoxy-D-glucose suppliers

Properties

Melting point:: 146-147 °C(lit.)

alpha: 45.5 º (c=2, H2O)

Boiling point:: 211.61°C (rough estimate)

Density: 1.1738 (rough estimate)

refractive index: 46.5 ° (C=1, H2O)

storage temp.: 2-8°C

solubility: H₂O: 50 mg/mL, clear, colorless to faintly yellow

form: crystalline

pka: pK1:12.52 (25°C)

color: white

optical activity: +38.5 → +45.9

biological source: synthetic

Water Solubility: Soluble in water.

Merck: 14,2904

BRN: 1723331

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day.

InChIKey: PMMURAAUARKVCB-CEZCPVKQSA-N

LogP: -1.460 (est)

CAS DataBase Reference: 154-17-6(CAS DataBase Reference)

EPA Substance Registry System: D-arabino-Hexose, 2-deoxy- (154-17-6)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319

Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes: Xn,Xi

Risk Statements: 20/21/22-36/37/38

Safety Statements: 24/25-37/39-36-26

WGK Germany: 3

RTECS: MQ3325000

F: 3-10

TSCA: Yes

HS Code: 29400090

Hazardous Substances Data: 154-17-6(Hazardous Substances Data)

Use

2-deoxy-D-Glucose is a non-metabolizable glucose analog that inhibits phosphorylation of glucose by hexokinase, the first step of glycolysis. This results in the depletion in cellular ATP, the inhibition of protein glycosylation, and the disruption of ER quality control by inducing the unfolded protein response. 2-deoxy-D-Glucose has been shown to cause cell cycle inhibition and cell death in in vitro models of hypoxia, induce autophagy, increase reactive oxygen species production, activate AMPK, and block tumor cell growth in animal models.[Cayman Chemical]

You can find 2-Deoxy-D-glucose suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.