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ChemicalBook >> CAS DataBase List >>AGI6780

AGI6780 suppliers

AGI6780

CAS:
1432660-47-3
MF:
C21H18F3N3O3S2
MW:
481.51

Properties

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥22.25 mg/mL in DMSO; insoluble in H2O; ≥100.8 mg/mL in EtOH
pka
11.78±0.20(Predicted)
form 
solid
color 
White to off-white
InChI
1S/C21H18F3N3O3S2/c22-21(23,24)14-2-1-3-16(10-14)25-20(28)26-19-11-17(32(29,30)27-15-4-5-15)6-7-18(19)13-8-9-31-12-13/h1-3,6-12,15,27H,4-5H2,(H2,25,26,28)
InChIKey
CCAWRGNYALGPQH-UHFFFAOYSA-N
SMILES
FC(F)(F)c1cc(ccc1)NC(=O)Nc2c(ccc(c2)[S](=O)(=O)NC4CC4)c3c[s]cc3

Safety Information

Symbol(GHS) 
Exclamation Mark (GHS07)
GHS07
Signal word 
Warning
Hazard statements 
H315-H319-H335
Precautionary statements 
P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
WGK Germany 
WGK 3
HS Code 
2935909099
Storage Class
11 - Combustible Solids

Use

AGI-6780 potently reduce (R)-2-hydroxyglutarate (2HG) levels in cell lines ectopically overexpressing IDH2/R140Q with EC50 of 20 nM, with excellent selectivity against other dehydrogenases. AGI-6780 reverses the IDH2/R140Q-induced differentiation block in TF-1 cells, and induces blast differentiation in primary human IDH2/R140Q AML patient samples.

89 supplier list of "AGI6780"

  • Product Name:AGI6780
  • Products Intro:Purity: 98% | Package: 1KG
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:AGI6780
  • Products Intro:Purity: 99% HPLC|Package: 5mg;0USD|1g;0USD|500g;0USD|25KG;0USD|200KG;0USD
  • Company Type: Trader
  • Country/Region: CHINA
AGI-6780 AGI-6780 2Photos

$31.00-122.00

  • Product Name:AGI-6780
  • Products Intro:Purity: 98.19% | Package: 1mg;31USD|5mg;72USD|10mg;122USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:AGI-6780
  • Products Intro:CustNote: Please reach out to us for more information about custom solutions.
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Product Name:AGI6780
  • Products Intro:Package: 1KG;25kg;200kg;1000kg Elin | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Electronic material intermediates,OLED,ppb grade Monomer,Pharmaceutical intermediates,KrF/ArF Monomer
  • Product Name:AGI-6780
  • Products Intro:Purity: >=98% | Package: $88.9/5mg;$147.9/10mg;$494.9/50mg;Bulk package | CustNote: 98%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
  • Product Name:AGI-6780
  • Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A854357
  • Company Type: Reagent
  • Country/Region: CHINA
  • 25 mg$352.00
  • Product Name:AGI6780
  • Products Intro:Brand:Axon Medchem | Product Number:Axon2274 | Purity:99%
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Product Name:AGI-6780
  • Products Intro:Brand:chiralstar | Product Number:scs-1019
  • Company Type: Trader
  • Country/Region: UNITED STATES
IDH2Inhibitor,R140QSomaticMutant-Specific,AGI-6780-CAS1432660-47-3-Calbiochem
  • Product Name:IDH2Inhibitor,R140QSomaticMutant-Specific,AGI-6780-CAS1432660-47-3-Calbiochem
  • Products Intro:Brand:sigma aldrich | Product Number:5.09880 | Purity:Acell-permeableinhibitorofisocitratedehydrogenase2R140Qmutant-containingdimers.H
  • Company Type: Trader
  • Country/Region: INDIA
You can find AGI6780 suppliers, manufacturers, and distributors from countries such as CHINA, United States and the The Netherlands here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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