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ChemicalBook >> CAS DataBase List >>Bleomycin

Bleomycin suppliers

Bleomycin

CAS:
11056-06-7
MF:
C110H168N34O46S7
MW:
2927.17

Properties

storage temp. 
2-8°C
solubility 
H2O: 20 mg/mL
form 
powder
color 
white
IARC
2B (Vol. 26, Sup 7) 1987, 1 (Vol. 76, 100A) 2012
EPA Substance Registry System
Bleomycin (11056-06-7)

Safety Information

Hazard Codes 
T
Risk Statements 
46-40
Safety Statements 
53-36/37-45
WGK Germany 
3
RTECS 
EC5991990
10
Hazardous Substances Data
11056-06-7(Hazardous Substances Data)
Toxicity
dog,LD,oral,> 100mg/kg (100mg/kg),Japanese Journal of Antibiotics. Vol. 28, Pg. 1, 1975.

Use

Bleomycin is a glycopeptide antibiotic complex isolatedfrom Streptomyces verticillus initially by Umezawa.Atleast 13 different fractions of bleomycin have been isolatedwith the clinically used product (Blenoxane) being a mixtureof predominantly A22 (55%–70%) and B2 (25%–32%)fractions.Of these fractions, A2 appears to possessthe greatest antineoplastic activity. Copper is found inthe naturally occurring material, and its removal is importantfor the material used clinically because it significantlyreduces activity.Bleomycin is notable for its lack of myelotoxicity, andthis allows it to be combined with other myelosuppressantswithout a resulting additive effect. The acute toxicities seenwith bleomycin are erythema (reddening of the skin), hyperpigmentation(skin darkening) found predominately on theextremities, and pulmonary toxicity. The pulmonary toxicitymay first occur as pneumonitis (inflammation of lung tissue),which normally responds to glucocorticosteroid therapy.Chronic pulmonary toxicity is expressed as pulmonaryfibrosis, which is irreversible and limits utility of the agent.

91 supplier list of "Bleomycin"

  • Product Name:Bleomycin
  • Products Intro:Purity: 99.9% | Package: 1kg|25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide
  • Product Name:Bleomycin
  • Products Intro:Purity: 98% | Package: 1KG
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:bleomycin
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Bleomycin
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Gamma-butyrolactone
  • Product Name:Bleomycin
  • Products Intro:Purity: 98% | Package: 1mg|25mg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Linoleic Acid,Vitamin B12,Riboflavin,β-Nicotinamide Mononucleotide,Amoxicillin trihydrate
  • Product Name:Bleomycin
  • Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
  • Product Name:Bleomycin
  • Products Intro:Purity: 99% | Package: 1KG;25kg;200kg;1000kg Jessica | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Electronic material intermediates,OLED,ppb grade Monomer,Pharmaceutical intermediates,KrF/ArF Monomer
  • Product Name:Bleomycin
  • Products Intro:Purity: 99.99% | Package: 25kg/drum
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Benzaldehyde,Butyraldehyde,Benzene,resin,Acetic acid
  • Product Name:BLM
  • Products Intro:Purity: > 99% | Package: 50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 | CustNote: Blooms Syndrome Protein Blm; BLM; BLM_HUMAN; Bloom Syndrome; Bloom syndrome protein; Bloom syndrome RecQ helicase like; BS; DNA Helicase; DNA helicase RecQ like type 2; MGC126616;
  • Company Type: Service provider
  • Country/Region: CHINA
Bleomycin
  • Product Name:Bleomycin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: INDIA
You can find Bleomycin suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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