Diosmin manufacturers and suppliers

Diosmin suppliers

Properties

Melting point:: 277-278°C

Boiling point:: 926.8±65.0 °C(Predicted)

Density: 1.68±0.1 g/cm3(Predicted)

vapor pressure: 0Pa at 20℃

storage temp.: Sealed in dry,2-8°C

solubility: Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides.

pka: 6.10±0.40(Predicted)

form: Solid

color: Pale Beige to Brown

Water Solubility: Soluble in DMSO (50 mg/ml), water (122 mg/ml at 25°C), and ethanol (<1 mg/ml at 25°C).

λmax: 345nm(EtOH)(lit.)

Merck: 14,3297

Major Application: food and beverages

Cosmetics Ingredients Functions: ANTIOXIDANT

InChIKey: GZSOSUNBTXMUFQ-YFAPSIMESA-N

SMILES: COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2

LogP: 0.14 at 20℃

CAS DataBase Reference: 520-27-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H412

Precautionary statements: P501-P273-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36-36/37-24/25

WGK Germany: 3

HS Code: 29381000

Storage Class: 11 - Combustible Solids

Use

Diosmin is an agonist of the aryl hydrocarbon receptor (AhR) and exhibits anti-proliferative and anti-inflammatory. It is used in the treatment of venous disease, i.e., chronic venous insufficiency (CVI) and hemorrhoidal disease (HD). Diosmin also reduces capillary hyperpermeability and expression of endothelial adhesion molecules (ICAM1, VCAM1). It effectively inhibits the P-glycoprotein (Pgp)-mediated efflux in cells.

You can find Diosmin suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.