EAI-045 suppliers
EAI-045
- CAS:
- 1942114-09-1
- MF:
- C19H14FN3O3S
- MW:
- 383.4
Suppliers by country/region
Company Type
Properties
- Density
- 1.546±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- ≥38.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- pka
- 7.20±0.50(Predicted)
- form
- solid
- color
- White to khaki
- InChI
- InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
- InChIKey
- YTUFHOKUFOQRDF-UHFFFAOYSA-N
- SMILES
- C(C1C=C(F)C=CC=1O)(N1CC2=CC=CC=C2C1=O)C(=O)NC1SC=CN=1
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Use
EAI045 is a potent and selective EGFR inhibitor (fourth generation). EAI045 targets selected drug-resistant EGFR mutants without affecting the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays. Therefore, it is a potential candidate drug for the treatment of related non-small cell lung cancer (NSCLC). It should be noted that EAI-045 is effectively in targeting the EGFR C797S mutation, which is resistance to the third-generation EGFR inhibitors including AZD9291 (osimertinib) and CO-1686 (rociletinib).
79 supplier list of "EAI-045"
- Product Name:N-(3-((5-fluoroethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide (EAI-045)
- Products Intro:Purity: 0.99 | Package: 5KG;1KG | CustNote: Have any requirements, pls contact sales@zetchem.com
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceutical, agrochemical, speciality chemical and liquid crystal industries.
- Product Name:EAI045
- Products Intro:Package: 50 mg | CustNote: Reach out to us for more information about custom solutions.
- Company Type: Trader
- Country/Region: UNITED STATES
$9.80/ 1.8KG
- Product Name:EAI-045
- Products Intro:Purity: >=99% | Package: 1.8KG;9.8USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl-2H-Isoindole-2-acetamide
- Products Intro:Purity: 99% | Package: 1kg; 25kg; or larger package as required
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Specialty chemicals,OLED materials,Custom synthesis service
- Product Name:EAI045
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:EAI-045
- Products Intro:Purity: 98% | Package: 500g，1kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Nucleosides,Nucleotides,Amino acidsAmino Acid & Peptides,Carbohydrates,Ionic Liquids
- Product Name:EAI045
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:EAI-045
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:EAI045
- Products Intro:Purity: 95% | Package: $42.9/10mg;$88.9/25mg;$147.9/50mg;$246.9/100mg;$444.9/200mg;Bulk package | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:EAI-045
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A858164
- Company Type: Reagent
- Country/Region: CHINA
You can find EAI-045 suppliers,
manufacturers, and distributors from countries such as China, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.